oncotomskСибирский онкологический журналSiberian journal of oncology1814-48612312-3168Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences10.21294/1814-4861-2019-18-3-5-13oncotomsk-1090Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯCLINICAL STUDIESИССЛЕДОВАНИЕ ПЕРИФЕРИЧЕСКИХ ЛИМФАТИЧЕСКИХ УЗЛОВ ПРИ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЯХ ГОЛОВЫ И ШЕИ С ИСПОЛЬЗОВАНИЕМ ЭЛАСТОГРАФИИ СДВИГОВОЙ ВОЛНОЙEXAMINATION OF PERIPHERAL LYMPH NODES USING SHEAR WAVE ELASTOGRAPHY IN PATIENTS WITH HEAD AND NECK CANCERhttps://orcid.org/0000-0002-7163-2553ЛежневД. А.LezhnevD. A.

Лежнев Дмитрий Анатольевич, доктор медицинских наук, профессор, заведующий кафедрой лучевой диагностики

г. Москва, 127473, ул. Делегатская, 20/11

SPIN-код: 6648-9613.

Researcher ID (WOS): B-6854-2018.

Author ID (Scopus): 24468778600

 

Dmitry A. Lezhnev, MD, DSc, Professor, Head of Diagnostic Imaging Department

20/1, Delegatskaya Street, 127473-Moscow

Researcher ID (WOS): B-6854-2018.

Author ID (Scopus): 24468778600

https://orcid.org/0000-0002-0635-4438ВасильевА. Ю.VasilyevA. Yu.

Васильев Александр Юрьевич, профессор, член-корреспондент РАН, доктор медицинских наук, кафедра лучевой диагностики

г. Москва, 127473, ул. Делегатская, 20/11

SPINкод: 3519-0938.

AuthorID (РИНЦ): 242494.

Researcher ID (WOS): O-8862-2017.

Author ID (Scopus): 7402046692

Aleksandr Yu. Vasilyev, MD, DSc, Professor, Corresponding Member RAS

20/1, Delegatskaya Street, 127473-Moscow

Researcher ID (WOS): O-8862-2017.

Author ID (Scopus): 7402046692

https://orcid.org/0000-0003-2580-5692ЕгороваЕ. А.EgorovaE. A.

Егорова Елена Алексеевна, доктор медицинских наук, профессор кафедры лучевой диагностики

г. Москва, 127473, ул. Делегатская, 20/11

SPIN-код: 3771-3676.

Researcher ID (WOS): O-7304-2017.

Author ID (Scopus): 57196761433

Elena A. Egorova, MD, DSc, Professor of the Diagnostic Imaging Department

20/1, Delegatskaya Street, 127473-Moscow

Researcher ID (WOS): O-7304-2017.

Author ID (Scopus): 57196761433

СмысленоваМ. В.SmyslenovaM. V.

Смысленова Маргарита Витальевна, доктор медицинских наук, профессор кафедры лучевой диагностики

г. Москва, 127473, ул. Делегатская, 20/11

Margarita V. Smyslenova, MD, DSc, Professor of the Diagnostic Imaging Department

20/1, Delegatskaya Street, 127473-Moscow

ТрутеньВ. П.TrutenV. P.

Трутень Виктор Павлович, доктор медицинских наук, профессор кафедры лучевой диагностики

г. Москва, 127473, ул. Делегатская, 20/11

Viktor P. Truten, MD, DSc, Professor of the Diagnostic Imaging Department

20/1, Delegatskaya Street, 127473-Moscow

https://orcid.org/0000-0001-8298-9913ПетровскаяВ. В.PetrovskayaV. V.

Петровская Виктория Васильевна, доктор медицинских наук, доцент кафедры лучевой диагностики

г. Москва, 127473, ул. Делегатская, 20/11

SPIN-код: 3086-5063

Viktoriia V. Petrovskaya, MD, DSc, Professor of the Diagnostic Imaging Department

20/1, Delegatskaya Street, 127473-Moscow

https://orcid.org/0000-0002-9014-9022ГромовА. И.GromovA. I.

Громов Александр Игоревич, доктор медицинских наук, профессор кафедры лучевой диагностики

г. Москва, 127473, ул. Делегатская, 20/11

SPIN-код: 6842-8684

Aleksandr I. Gromov, MD, DSc, Professor of the Diagnostic Imaging Department

20/1, Delegatskaya Street, 127473-Moscow

КосташО. В.KostashO. V.

Косташ Ольга Владимировна, врач отделения ультразвуковой

Московская область, Красногорский район, 143423, п/о Степановское, п. Истра, 27

диагностики

SPIN-код: 9188-4429

Оlga V. Kostash, MD, Ultrasound Diagnostics Department

27, Istra, 143423-Krasnogorsk district, Moscow region

kostash2012@yandex.ruКабинЮ. В.KabinYu. V.

Кабин Юрий Вячеславович, кандидат медицинских наук, врач отделения ультразвуковой диагностики

Московская область, Красногорский район, 143423, п/о Степановское, п. Истра, 27

SPIN-код: 5502-9412

Yury V. Kabin, MD, PhD, Ultrasound Diagnostics Department

27, Istra, 143423-Krasnogorsk district, Moscow region

https://orcid.org/0000-0002-3771-1354КапустинВ. В.KapustinV. V.

Капустин Владимир Викторович доктор медицинских наук, заведующий отделением ультразвуковой диагностики, Московская городская онкологическая больница № 62, Московский государственный медико-стоматологический университет им. А.И. Евдокимова

Московская область, Красногорский район, 143423, п/о Степановское, п. Истра, 27

SPIN-код: 2056-1115

Vladimir V. Kapustin, MD, PhD, Head of Ultrasound Diagnostics Department

27, Istra, 143423-Krasnogorsk district, Moscow region

Московский государственный медико-стоматологический университет имени А.И. ЕвдокимоваРоссияMoscow State University of Medicine and Dentistry named after EvdokimovRussian FederationГБУЗ города Москвы «Московская городская онкологическая больница № 62 Департамента здравоохранения города Москвы»РоссияMoscow Municipal Cancer Hospital №62Russian Federation201929062019183513Copyright © Лежнев Д.А., Васильев А.Ю., Егорова Е.А., Смысленова М.В., Трутень В.П., Петровская В.В., Громов А.И., Косташ О.В., Кабин Ю.В., Капустин В.В., 20192019Лежнев Д.А., Васильев А.Ю., Егорова Е.А., Смысленова М.В., Трутень В.П., Петровская В.В., Громов А.И., Косташ О.В., Кабин Ю.В., Капустин В.В.Lezhnev D.A., Vasilyev A.Y., Egorova E.A., Smyslenova M.V., Truten V.P., Petrovskaya V.V., Gromov A.I., Kostash O.V., Kabin Y.V., Kapustin V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.siboncoj.ru/jour/article/view/1090

Between December and September 2018 123 patients with head and neck tumors underwent ultrasound examination. The median age of the patients was 57 years (range 19–76 years). Metastatic lymph nodes were suspected in all patients. A fine needle aspiration biopsy was performed prior to treatment. Aplio 500 (Тoshiba, Japan) ultrasound device was used. According to findings of cytological examination, all patients were divided into 2 groups. Group I consisted of 58 patients with cytologically confirmed metastatic lymph nodes. Group II comprised 65 patients with lymphoid reticular hyperplasia. The values of Young’s modulus for metastatic lymph nodes were: median – 134.2 kPa, 2.5–97.5 percentiles – 7.3–181.7 kPa. The corresponding values for hyperplastic lymph nodes were: 20.1 kPa, 6.9–138.3 kPa. Thus, significant differences in the values of Young’s modulus between metastatic and hyperplastic lymph nodes were detected in patients with head and neck cancer (p<0.001). The best diagnostic values for detecting metastatic lymph nodes in patients with head and neck cancer were achieved with a threshold value of the Young’s modulus of 33.2 kPa (sensitivity – 89.7 %, specificity – 84.6 %), AU C – 0.899. The values of the Young’s modulus in the metastatic lymph nodes did not depend on the primary tumor and on the localization of the lymph nodes studied (submandibular, paratracheal, cervical, supraclavicular groups).

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The authors declare that there are no conflicts of interest present.