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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-113</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>ЛУЧЕВАЯ ТЕРАПИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ С УЧЕТОМ ФАКТОРОВ ПРОГНОЗА</article-title><trans-title-group xml:lang="en"><trans-title>RADIATION THERAPY OF BREAST CANCER WITH ACCOUNT PROGNOSTIC FACTORS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симонов</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Simonov</surname><given-names>K. A.</given-names></name></name-alternatives><email xlink:type="simple">simonov_ka@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Старцева</surname><given-names>Ж. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Startseva</surname><given-names>Zh. A.</given-names></name></name-alternatives><email xlink:type="simple">simonov_ka@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слонимская</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Slonimskaya</surname><given-names>E. M.</given-names></name></name-alternatives><email xlink:type="simple">simonov_ka@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Томский НИИ онкологии; Национальный исследовательский Томский политехнический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk Cancer Research Institute; National Research Tomsk Polytechnic University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Томский НИИ онкологии; Сибирский государственный медицинский университет,  Томск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk Cancer Research Institute; Siberian State Medical University, Tomsk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>16</day><month>02</month><year>2016</year></pub-date><volume>1</volume><issue>1</issue><fpage>76</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Симонов К.А., Старцева Ж.А., Слонимская Е.М., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Симонов К.А., Старцева Ж.А., Слонимская Е.М.</copyright-holder><copyright-holder xml:lang="en">Simonov K.A., Startseva Z.A., Slonimskaya E.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/113">https://www.siboncoj.ru/jour/article/view/113</self-uri><abstract><p>Обзор посвящен применению послеоперационной лучевой терапии у больных раком молочной железы после выполнения радикальной мастэктомии. Подчеркивается необходимость дифференцированного подхода к лучевой терапии, который должен базироваться на оценке клинико-морфологических факторов, определяющих риск развития локо-регионарного рецидива РМЖ.</p></abstract><trans-abstract xml:lang="en"><p>This review about the application of radiotherapy in breast cancer patients after radical mastectomy. Emphasizes the need for a differentiated approach to radiation therapy, which should be based on the definition of clinical morphological factors that determine the risk of loco-regional recurrence of breast cancer.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>радикальная мастэктомия</kwd><kwd>рецидив</kwd><kwd>адъювантная лучевая терапия</kwd><kwd>факторы прогноза</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>radical mastectomy</kwd><kwd>locoregional recurrence</kwd><kwd>adjuvant radiation therapy</kwd><kwd>prognostic factors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ефимкина Ю.В., Гладилина И.А., Шабанов М.А. 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