oncotomskСибирский онкологический журналSiberian journal of oncology1814-48612312-3168Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences10.21294/1814-4861-2020-19-2-116-124oncotomsk-1407Research ArticleОБЗОРЫREVIEWSНутритивная недостаточность и терапия онкологических пациентов. Современный взгляд на проблемуNutritional insufficiency and therapy for cancer patients. Modern view on the problemhttps://orcid.org/0000-0002-8509-4338ГамееваЕ. В.GameevaE. V.

Гамеева Елена Владимировна - кандидат медицинских наук, заместитель директора по лечебной работе, SPIN-код: 9423-7155. AuthorID (РИНЦ): 294656. Researcher ID (WOS): AAD-3025-2020. AuthorID (Scopus): 6504612323.

125284, Москва, 2-й Боткинский проезд, 3

Elena V. Gameeva - MD, PhD, Deputy Director for Medical Work, Researcher ID (WOS): AAD-3025-2020. Author ID (Scopus): 6504612323.

3, the 2-nd Botkinsky pr., 125284, Moscow

gameeva@yandex.ruhttps://orcid.org/0000-0001-8845-9913ХороненкоВ. Э.KhoronenkoV. E.

Хороненко Виктория Эдуардовна - доктор медицинских наук, руководитель отдела анестезиологии и реанимации, SPIN-код: 1971-6546. AuthorID (РИНЦ): 467560. AuthorID (Scopus): 23497024000.

125284, Москва, 2-й Боткинский проезд, 3

Viktoriya E. Khoronenko - MD, DSc, Head of Anesthesiology and Resuscitation Department, Author ID (Scopus): 23497024000.

3, the 2-nd Botkinsky pr., 125284, Moscow

https://orcid.org/0000-0003-0872-1825ШеметоваМ. М.ShemetovaM. M.

Шеметова Мария Михайловна - кандидат медицинских наук, старший научный сотрудник отдела анестезиологии и реанимации, SPIN-код: 5861-6920. AuthorID (РИНЦ): 718961.

125284, Москва, 2-й Боткинский проезд, 3

Mariya M. Shemetova - MD, PhD, Senior Researcher, Department of Anaesthesiology and Resuscitation.

3, the 2-nd Botkinsky pr., 125284, Moscow

МНИОИ им. П.А. Герцена - Филиал ФГБУ «НМИЦ радиологии» Минздрава РоссииРоссияP.A. Hertsen Moscow Oncology Research Institute - Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationRussian Federation202029042020192116124Copyright © Гамеева Е.В., Хороненко В.Э., Шеметова М.М., 20202020Гамеева Е.В., Хороненко В.Э., Шеметова М.М.Gameeva E.V., Khoronenko V.E., Shemetova M.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.siboncoj.ru/jour/article/view/1407Введение

Введение.Метаболические изменения вследствие прогрессирования злокачественных новообразований и негативных последствий агрессивных методов его лечения приводят к снижению потребления пищи у пациентов, что способствует развитию синдрома анорексии-кахексии у онкологических больных из-за сложных взаимодействий между провоспалительными цитокинами и метаболизмом хозяина. Помимо физических и метаболических последствий, пациенты, получающие лечение по поводу злокачественных новообразований, часто страдают от психологических расстройств, включая депрессию.

Материал и методы

Материал и методы. С целью оценки эффективности дополнительных пероральных методов нутритивной поддержки онкологических пациентов был осуществлен поиск и анализ актуальных данных по научным базам PubMed и Medline.

Результаты

Результаты. Нутритивная поддержка положительно влияет на исходы онкологического лечения и снижает частоту осложнений путем оптимизации баланса между затратами энергии и потреблением пищи. В паллиативной помощи пищевая поддержка направлена на улучшение качества жизни пациента путем контроля таких симптомов, как тошнота, рвота и болевой синдром, связанный с приемом пищи.

 

 

Background

Background. Metabolic changes due to the progression of cancer and its aggressive treatment, lead to decreased food intake, related with development of cancer anorexia-cachexia syndrome (CACS) because of the complex interactions between pro-inflammatory cytokines and host metabolism. Beyond the physical and the metabolic consequences, cancer patients are often suffering from psychological distress, including depression.

Material and Methods

Material and Methods. A literature search and analysis of data was conducted in PubMed and Medline databases since 2000 with the purpose to evaluate the effectiveness of additional oral methods of nutritional support for cancer patients.

Results

Results. Nutritional support has a positive effect on response to cancer therapy and reduces the incidence of complications by optimizing the balance between energy expenditure and food consumption. In palliative care, nutritional support aims at improving patient’s quality of life by controlling symptoms such as nausea, vomiting and pain related to food intake.

Conclusion

Conclusion. The literature review confirms that nutritional intervention has a direct impact on quality of life and should be integrated into the global cancer care because of its significant contribution to QoL. Furthermore, monitoring and correction of nutritional status should be an integral part of the quality of life assesses with the aim to optimize its adequacy to the patient’s needs and expectations.

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The authors declare that there are no conflicts of interest present.