oncotomskСибирский онкологический журналSiberian journal of oncology1814-48612312-3168Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences10.21294/1814-4861-2020-19-5-88-96oncotomsk-1583Research ArticleОБЗОРЫREVIEWSМЕТОДЫ ДИАГНОСТИКИ СТОРОЖЕВОГО ЛИМФАТИЧЕСКОГО УЗЛА У БОЛЬНЫХ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫMETHODS FOR SENTINEL LYMPH NODE DETECTION IN PATIENTS WITH BREAST CANCERhttps://orcid.org/0000-0001-7141-2502ЗикиряходжаевА. Д.ZikiryakhodzhaevA. D.

доктор медицинских наук, руководитель отделения реконструктивно-пластической хирургии молочной железы и кожи,

125284, г. Москва, 2-й Боткинский проезд, 3;

119991, г. Москва, ул. Большая Пироговская, 2/4

MD, DSc, Head of Department of Reconstructive Surgery for Breast Cancer,

3, 2nd Botkinsky proezd, 125284-Moscow;

2, Bolshaya Pirogovskaya Street, 119991-Moscow

mariannastarkova@gmail.comhttps://orcid.org/0000-0002-0945-4266ГрушинаТ. И.GrushinaT. I.

доктор медицинских наук, заведующая отделом физических методов лечения,

105120, г. Москва, ул. Земляной Вал, 53

MD, DSc, Head of Department of Physical Treatment Methods, 

53, Zemlyanoy Val, 105120-Moscow

https://orcid.org/0000-0003-4141-8414СтарковаМ. В.StarkovaM. V.

врач-онколог общеклинического отдела,

125284, г. Москва, 2-й Боткинский проезд, 3

MD,

3, 2nd Botkinsky proezd, 125284-Moscow

https://orcid.org/0000-0002-3860-450XКазарянЛ. П.KazaryanL. P.

врач-онколог общеклинического отдела, 125284, г. Москва, 2-й Боткинский проезд, 3;

аспирант кафедры онкологии, радиотерапии и пластической хирургии, 119991, г. Москва, ул. Большая Пироговская, 2/4

MD, 3, 2nd Botkinsky proezd, 125284-Moscow;

post-graduate, of the Department of Oncology, Radiotherapy and Plastic Surgery, 2, Bolshaya Pirogovskaya Street, 119991-Moscow

https://orcid.org/0000-0001-8187-7450ВолковаЮ. И.VolkovaYu. I.

врач-хирург общеклинического отдела,

125284, г. Москва, 2-й Боткинский проезд, 3

MD,

3, 2nd Botkinsky proezd, 125284-Moscow

https://orcid.org/0000-0001-9195-4181БагдасароваД. В.BagdasarovaD. V.

клинический аспирант,

125284, г. Москва, 2-й Боткинский проезд, 3

Post-graduate, 

3, 2nd Botkinsky proezd, 125284-Moscow

https://orcid.org/0000-0002-9509-1931АблицоваН. В.AblitsovaN. V.

кандидат медицинских наук, врач-онколог отделения реконструктивно-пластической хирургии молочной железы и кожи,

125284, г. Москва, 2-й Боткинский проезд, 3

MD, PhD, Department of Reconstructive Surgery for Breast Cancer,

3, 2nd Botkinsky proezd, 125284-Moscow

https://orcid.org/0000-0002-7817-5324СкрепцоваН. С.SkreptsovaN. S.

кандидат медицинских наук, старший научный сотрудник отделения ультразвуковой диагностики,

125284, г. Москва, 2-й Боткинский проезд, 3

MD, PhD, Senior Researcher, Department of Ultrasound Imaging,

3, 2nd Botkinsky proezd, 125284-Moscow

УсовФ. Н.UsovF. N.

кандидат медицинских наук, врач-онколог отделения реконструктивно-пластической хирургии молочной железы и кожи,

125284, г. Москва, 2-й Боткинский проезд, 3

MD, PhD, Department of Reconstructive Surgery for Breast Cancer, 

3, 2nd Botkinsky proezd, 125284-Moscow

Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Министерства здравоохранения РФ; ГБОУ ВПО «Первый МГМУ им. И.М. Сеченова» Министерства здравоохранения РФРоссияP.A. Hertsen Moscow Oncology Research Center- branch of National Medical Research Radiological Center of the Ministry of Healthcare of the Russian Federation; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Russian FederationМосковский научно-практический центр медицинской реабилитации, восстановительной и спортивной медицины Департамента здравоохранения города МосквыРоссияMoscow Research and Practical Centre for Medical Rehabilitation, Restorative and Sports Medicine, Moscow Health DepartmentRussian FederationМосковский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Министерства здравоохранения РФРоссияP.A. Hertsen Moscow Oncology Research Center- branch of National Medical Research Radiological Center of the Ministry of Healthcare of the Russian FederationRussian Federation2020281020201958896Copyright © Зикиряходжаев А.Д., Грушина Т.И., Старкова М.В., Казарян Л.П., Волкова Ю.И., Багдасарова Д.В., Аблицова Н.В., Скрепцова Н.С., Усов Ф.Н., 20202020Зикиряходжаев А.Д., Грушина Т.И., Старкова М.В., Казарян Л.П., Волкова Ю.И., Багдасарова Д.В., Аблицова Н.В., Скрепцова Н.С., Усов Ф.Н.Zikiryakhodzhaev A.D., Grushina T.I., Starkova M.V., Kazaryan L.P., Volkova Y.I., Bagdasarova D.V., Ablitsova N.V., Skreptsova N.S., Usov F.N.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.siboncoj.ru/jour/article/view/1583

Цель исследования – представить различные методы диагностики сторожевых лимфатических узлов, рассмотрев их достоинства и недостатки.

Материал и методы

Материал и методы. Проведен поиск статей, опубликованных в базах Pubmed, MedLine, РИНЦ, РГБ за 1970–2018 гг. Из 150 проанализированных публикаций в обзор вошли 50.

Результаты

Результаты. В настоящее время биопсия сторожевого лимфатического узла (СЛУ) стала достойной альтернативой традиционной хирургии на лимфатических путях при раннем раке молочной железы (РМЖ). Благодаря данной методике снизилось количество послеоперационных осложнений, вызванных лимфодиссекцией, а качество жизни больных значительно возросло. С момента появления и до настоящего времени накопилось большое количество техник определения СЛУ, каждая из которых имеет свои плюсы и минусы.

Заключение

Заключение. Несмотря на большое количество методов детекции СЛУ, вопрос об оптимальной технике в настоящее время остается дискуссионным. 

Objective

Objective: to provide various methods for sentinel lymph node detection considering their advantages and disadvantages.

Material and Methods

Material and Methods. The search of the relevant articles published in Pubmed, MedLine, RINTs, etc. database was conducted. 49 publications from 1970 to 2018 were analyzed.

Results

Results. Currently, sentinel lymph node biopsy (SLN biopsy) has become a worthy alternative to traditional lymphatic surgery for early breast cancer. SLN biopsy significantly decreases the number of postoperative complications caused by lymphadenectomy and improves the quality of life of cancer patients. So far, a large number of SLN detection techniques have accumulated. Each of these techniques has its own advantages and disadvantages.

Conclusion

Conclusion. Despite a large number of SLN detection methods, the question of the optimal technique is currently debatable. 

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The authors declare that there are no conflicts of interest present.