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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2021-20-6-88-95</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-1990</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОПЫТ РАБОТЫ ОНКОЛОГИЧЕСКИХ УЧРЕЖДЕНИЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ONCOLOGY PRACTICE</subject></subj-group></article-categories><title-group><article-title>Микрохирургическая реконструкция основания черепа и средней зоны лица после орбито-максиллярных резекций по поводу злокачественных опухолей</article-title><trans-title-group xml:lang="en"><trans-title>Microsurgical reconstruction of the skull base and midface after orbitomaxillary resections for malignant tumors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7534-6565</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болотин</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bolotin</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, старший научный сотрудник</p><p>SPIN-код: 6105-5486</p><p> Россия, 115478, г. Москва, Каширское шоссе, 23 </p></bio><bio xml:lang="en"><p> MD, PhD, Senior Researcher</p><p> 23, Kashirskoe shosse, 115478, Moscow, Russia </p></bio><email xlink:type="simple">bolotin1980@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1255-5700</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мудунов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Mudunov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p> доктор медицинских наук, заведующий отделением, </p><p>SPIN-код: 3516-6616</p><p> Россия, Московская обл., Одинцовский р-н, д. Лапино, 1-е Успенское шоссе, 111 </p></bio><bio xml:lang="en"><p> MD, DSc, Head of the Department</p><p> 111, Uspenskoye Shosse, Lapino, Odintsovky District, Moscow region, Russia </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3668-0741</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соболевский</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobolevsky</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, заведующий отделением </p><p> Россия, 115478, г. Москва, Каширское шоссе, 23 </p></bio><bio xml:lang="en"><p> MD, DSc, Head of the Department</p><p>  23, Kashirskoe shosse, 115478, Moscow, Russia </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4496-6128</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гельфанд</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Gelfand</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p> кандидат медицинских наук, врач-онколог</p><p>SPIN-код: 7641-2039</p><p> Россия, 115478, г. Москва, Каширское шоссе, 23 </p></bio><bio xml:lang="en"><p> MD, PhD, Oncologist </p><p> 23, Kashirskoe shosse, 115478, Moscow, Russia </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1578-3450</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> ординатор</p><p>SPIN-код: 6893-5113</p><p> Россия, 115478, г. Москва, Каширское шоссе, 23 </p></bio><bio xml:lang="en"><p> MD, Resident </p><p> 23, Kashirskoe shosse, 115478, Moscow, Russia </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9543-990X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахундов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhundov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> доктор медицинских наук, старший научный сотрудник</p><p>SPIN-код: 8895-9447</p><p> Россия, 115478, г. Москва, Каширское шоссе, 23 </p></bio><bio xml:lang="en"><p> MD, DSc, Senior Researcher </p><p> 23, Kashirskoe shosse, 115478, Moscow, Russia </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Клинический госпиталь «Лапино»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Hospital «Lapino» </institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>12</day><month>01</month><year>2022</year></pub-date><volume>20</volume><issue>6</issue><fpage>88</fpage><lpage>95</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Болотин М.В., Мудунов А.М., Соболевский В.А., Гельфанд И.М., Орлова И.В., Ахундов А.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Болотин М.В., Мудунов А.М., Соболевский В.А., Гельфанд И.М., Орлова И.В., Ахундов А.А.</copyright-holder><copyright-holder xml:lang="en">Bolotin M.V., Mudunov A.M., Sobolevsky V.A., Gelfand I.M., Orlova I.V., Akhundov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/1990">https://www.siboncoj.ru/jour/article/view/1990</self-uri><abstract><p>Введение. Орбито-максиллярная резекция подразумевает под собой экзентерацию содержимого орбиты с резекцией нижнеглазничной и медиальной стенок. Основными задачами реконструкции являются: пластика мягкотканого дефекта и дефекта костных структур, тампонада полости орбиты и/или ее подготовка для дальнейшего глазного протезирования, реконструкция дефекта основания черепа. Цель исследования – представить непосредственные результаты орбито-максиллярных резекций у больных с обширными злокачественными новообразованиями средней зоны лица. Материал и методы. В отделении опухолей головы и шеи НМИЦ онкологии им. Н.Н. Блохина за период с 2014 по 2020 г. Под наблюдением находилось 6 пациентов. Во всех случаях дефект носил комбинированный характер. Для устранения дефекта, образовавшегося после резекции костных структур (верхняя челюсть, лобная, носовая кости) и кожных покровов в 3 (50%) случаях использован кожно-мышечный alt-лоскут, в 3 (50 %) – кожно-фасциальный лучевой лоскут. Результаты. Эстетический результат оценен у 6 больных. Во всех наблюдениях получен удовлетворительный результат. Ни у одного пациента, которому была выполнена резекция твердой мозговой оболочки с последующей пластикой, не отмечалось явлений ликвореи в послеоперационном периоде. Заключение. Выбор лоскута при орбито-максиллярной резекции зависит от объема дефекта. При небольшом объеме дефекта (до 70 см3) реконструкция может быть выполнена лучевым кожно-фасциальным лоскутом. При объеме дефекта более 71 см3 методом выбора является реконструкция с использованием кожно-мышечного alt-лоскута.</p></abstract><trans-abstract xml:lang="en"><p>Background. Orbitomaxillary resection includes exenteration of the orbital contents with resection of the inferior orbital and medial walls. The main goals are: reconstruction of soft tissue and bone structure defects, tamponade of the orbital cavity and/or its preparation for further ocular prosthetics, and reconstruction of the skull base defect. The purpose of the study to present the immediate results of orbitomaxillary resections in patients with malignant neoplasms of the skull base and midface. Material and methods. Between 2014 and 2020, 6 patients who previously underwent surgery for primary cancer (n=3) and recurrent cancer (n=3) were treated at the Head and Neck cancer department of N.N. Blokhin National medical Research center of oncology. To reconstruct defects after resection of bone structures (maxilla, frontal and nasal bones) and skin, a musculocutaneous alt-flap was used in 3 (50 %) cases and a fascial skin radial flap in 3 (50 %) cases. Results. The aesthetic result was assessed in 6 patients. In all cases, a satisfactory result was obtained. None of the patients who underwent resection of the dura mater followed by reconstruction had no symptoms of liquorrhea in the postoperative period. Conclusion. Flap selection depends on the defect size. In cases with a small defect size (up to 70 cm3), reconstruction with the radial fascial skin flap can be performed. If the defect size is more than 71 cm3, reconstruction with musculocutaneous alt flap can be the method of choice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>злокачественные новообразования средней зоны лица и основания черепа</kwd><kwd>орбито-максиллярные резекции</kwd><kwd>микрохирургическая реконструкция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>malignant tumors of the skull base and midface</kwd><kwd>orbitomaxillary resections</kwd><kwd>microsurgical&#13;
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