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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2023-22-5-14-27</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-2753</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EPIDEMIOGICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Анализ потерянных лет жизни в результате преждевременной смертности от злокачественных новообразований в Российской Федерации</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of years of life lost due to premature cancer mortality in the Russian Federation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3258-0954</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хайлова</surname><given-names>Ж. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khailova</surname><given-names>Zh. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хайлова Жанна Владимировна - кандидат медицинских наук, заместитель директора по организационно-методической работе, Медицинский радиологический научный центр им. А.Ф. Цыба – филиал ФГБУ «НМИЦР» Минздрава России; руководитель Центра координации деятельности учреждений регионов в области онкологии и радиологии, ФГБУ «НМИЦР» Минздрава России.</p><p>49031, Обнинск, ул. Маршала Жукова, 10; 125284, Москва, 2-й Боткинский пр-д, 3</p></bio><bio xml:lang="en"><p>Zhanna V. Khailova - MD, PhD, Deputy Director for organizational and methodological work, A.F. Tsyb MRRC – Branch of the National Medical Research Radiological Centre of the MHR; Head of the Center for Coordinating the Activities of Regional Institutions in the Field of Oncology and Radiology, National MRRC of the Ministryof Health of Russia.</p><p>10, marshala Zhukova st., Obninsk, 249031; 3, 2nd Botkinsky drive, Moscow, 125284</p></bio><email xlink:type="simple">1977zhanna@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8784-8415</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каприн</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaprin</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каприн Андрей Дмитриевич - доктор медицинских наук, профессор, академик РАН и РАО, заведующий кафедрой онкологии и рентгенорадиологии им. В.П. Харченко, ФГАОУ ВО «РУДН»; директор, МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИЦР» Минздрава России (г. Москва, Россия); генеральный директор, ФГБУ «НМИЦР» Минздрава России. SPIN-код: 1759-8101.</p><p>125284, Москва, 2-й Боткинский пр-д, 3; 125284, Москва, 2-й Боткинский пр-д, 3; 117198, Москва, ул. Миклухо-Маклая, 6</p></bio><bio xml:lang="en"><p>Andrej D. Kaprin - MD, Professor, Academician of the Russian Academy of Sciences, Head of Chair of Oncology and Radiology named after Kharchenko, RUDN University; Director, P.A. Hertsen Moscow Oncology Research Institute – Branch of the National MRRC of the MHR; Director General, A. Tsyb MRRC – Branch of the National MRRC of the MHR.</p><p>3, 2nd Botkinsky drive, Moscow, 125284; 6, Miklukho-Maklaya St., Moscow, 117198</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1581-0703</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Омельяновский</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Omelyanovsky</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Омельяновский Виталий Владимирович - доктор медицинских наук, профессор, генеральный директор, ФГБУ «ЦЭККМП» Минздрава России; заведующий кафедрой организации здравоохранения и общественного здоровья с курсом оценки технологий здравоохранения, ФГБОУ ДПО «РМАНПО» Минздрава России; руководитель Центра финансов здравоохранения, ФГБУ «НИФИ» Минфина России; главный научный сотрудник отдела экономических исследований в здравоохранении, ФГБНУ «ННИИОЗ имени Н.А. Семашко».</p><p>109028, Москва, Хохловский пер., 10/5; 125993, Москва, ул. Баррикадная, 2/1, стр. 1; 127006, Москва, Настасьинский пер., 3/2; 105064, Москва, ул. Воронцово поле, 12, стр. 1</p></bio><bio xml:lang="en"><p>Vitaliy V. Omelyanovskiy - MD, DSc, Professor, Director General, Center for Healthcare Quality Assessment and Controlof the MHR; Chief of Chair of Healthcare Organization and Public Health with a Course in Health Technology Assessment, RMACPE of the MHR; Head of Center for Healthcare Finance, FRIMFR; Chief Researcher of the Department of Economic Research in Healthcare, N.A. Semashko NRIPH.</p><p>10/5 Khokhlovsky per., Moscow, 109028; 2/1, Barrikadnaya st., build. 1, Moscow, 125993; 3/2, Nastasyinsky per., Moscow, 127006; 12, Vorontsovo pole st., build. 1, Moscow, 105064</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2198-3029</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пустовалов</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pustovalov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пустовалов Денис Николаевич - главный специалист, ФГБУ «ЦЭККМП» Минздрава России; научный сотрудник, ФГБОУ ВО «РАНХ и государственной службы при Президенте РФ».</p><p>109028, Москва, Хохловский пер., 10/5; 119571, Москва, пр. Вернадского, 82–84, корп. 9</p></bio><bio xml:lang="en"><p>Denis N. Pustovalov - Chief Expert, Center for Healthcare Quality Assessment and Controlof the MHR; Researcher, The RPA of National Economy and Public Administration.</p><p>10/5 Khokhlovsky per., Moscow, 109028; 82–84, Vernadskogo ave., bldg. 9, Moscow, 119571</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9465-0017</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агафонова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Agafonova</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Агафонова Юлия Андреевна - главный специалист, ФГБУ «ЦЭККМП» Минздрава России; аспирант, ФГБОУ ВО «МГМСУ им. А.И. Евдокимова» Минздрава России.</p><p>109028, Москва, Хохловский пер., 10/5; 127473, Москва, ул. Делегатская, 20, стр. 1</p></bio><bio xml:lang="en"><p>Yuliya A. Agafonova - MD, Chief Expert, Center for Healthcare Quality Assessment and Controlof the MHR; Postgraduate student, A.I. Evdokimov Moscow SUMedicine and Dentistry of the MHR.</p><p>10/5 Khokhlovsky per., Moscow, 109028; 20, delegatskaya st., build. 1, Moscow, 127473</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5882-1667</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кусакина</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Kusakina</surname><given-names>V. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кусакина Вера Олеговна - главный специалист.</p><p>109028, Москва, Хохловский пер., 10/5</p></bio><bio xml:lang="en"><p>Vera O. Kusakina - Chief Expert.</p><p>10/5 Khokhlovsky per., Moscow, 109028</p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7689-6032</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванов Сергей Анатольевич - доктор медицинских наук, член-корреспондент РАН, директор, Медицинский радиологический научный центр им. А.Ф. Цыба – филиал ФГБУ «НМИЦР» Минздрава России; профессор кафедры онкологии и рентгенорадиологии им. В.П. Харченко, ФГАОУ ВО «РУДН».</p><p>49031, Обнинск, ул. Маршала Жукова, 10; 117198, Москва, ул. Миклухо-Маклая, 6</p></bio><bio xml:lang="en"><p>Sergey A. Ivanov - MD, DSc, Corresponding Member of the Russian Academy of Sciences, Director, A. Tsyb Medical Radiological Research Centre – Branch of the National MRRC of the MHR; Professor of Chair of Oncology and Radiology named after Kharchenko, RUDN University. Author ID (Scopus): 16070399200.</p><p>10, marshala Zhukova st., Obninsk, 249031; 6, Miklukho-Maklaya St., Moscow, 117198</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9755-1164</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шегай</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shegai</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шегай Петр Викторович - кандидат медицинских наук, заместитель генерального директора по науке.</p><p>125284, Москва, 2-й Боткинский пр-д, 3</p></bio><bio xml:lang="en"><p>Petr V. Shegai - MD, PhD, Deputy General Director.</p><p>3, 2nd Botkinsky drive, Moscow, 125284</p></bio><xref ref-type="aff" rid="aff-8"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинский радиологический научный центр им. А.Ф. Цыба – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России; ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.F. Tsyb medical Radiological Research centre – Branch of the National Medical Research Radiological Centre of the Ministryof Health of the Russia; National Medical Research Radiological Centre of the Ministryof Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России; Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России; ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Radiological Centre of the Ministryof Health of Russia; P.A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre of the Ministryof Health of the Russia; Rudn University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ «Центр экспертизы и контроля качества медицинской помощи» Минздрава России; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ФГБУ «Научно-исследовательский финансовый институт» Минфина России; ФГБНУ «Национальный НИИ общественного здоровья им. Н.А. Семашко»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Healthcare Quality Assessment and Controlof the Ministry of Health of the Russia; Russian Medical Academy of Continuing Professional Education of the Ministry of Health of Russia; Financial Research institute of the ministry of Finance of the Russia; N.A. Semashko National Research Institute of Public Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБУ «Центр экспертизы и контроля качества медицинской помощи» Минздрава России; ФГБОУ ВО «Российская академия народного хозяйства и государственной службы при Президенте Российской Федерации»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Healthcare Quality Assessment and Controlof the Ministry of Health of the Russia; The Russian Presidential Academy of National Economy and Public Administration</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБУ «Центр экспертизы и контроля качества медицинской помощи» Минздрава России; ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Healthcare Quality Assessment and Controlof the Ministry of Health of the Russia; A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ФГБУ «Центр экспертизы и контроля качества медицинской помощи» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Healthcare Quality Assessment and Controlof the Ministry of Health of the Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>Медицинский радиологический научный центр им. А.Ф. Цыба – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России; ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.F. Tsyb medical Radiological Research centre – Branch of the National Medical Research Radiological Centre of the Ministryof Health of the Russia; Rudn University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Radiological Centre of the Ministryof Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>14</day><month>11</month><year>2023</year></pub-date><volume>22</volume><issue>5</issue><fpage>14</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хайлова Ж.В., Каприн А.Д., Омельяновский В.В., Пустовалов Д.Н., Агафонова Ю.А., Кусакина В.О., Иванов С.А., Шегай П.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Хайлова Ж.В., Каприн А.Д., Омельяновский В.В., Пустовалов Д.Н., Агафонова Ю.А., Кусакина В.О., Иванов С.А., Шегай П.В.</copyright-holder><copyright-holder xml:lang="en">Khailova Z.V., Kaprin A.D., Omelyanovsky V.V., Pustovalov D.N., Agafonova Y.A., Kusakina V.O., Ivanov S.A., Shegai P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/2753">https://www.siboncoj.ru/jour/article/view/2753</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Оценка бремени болезни позволяет проводить анализ интегрально, включая оценку причин и последствий. Показатель потерянных лет жизни в результате преждевременной смертности является частью анализа бремени болезни. Учитывая, что бремя злокачественных новообразований (ЗНО) неуклонно растет, анализ числа потерянных лет позволяет определить новые стратегические направления, а также скорректировать уже принятые решения в области здравоохранения онкологических пациентов.</p><p>Цель исследования – оценить потери продолжительности жизни в результате преждевременной смертности от ЗНО населения Российской Федерации (РФ).</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Анализ проведен с использованием международных статистических баз данных для оценки бремени заболеваний, баз данных Федеральной службы государственной статистики (Росстат). Для определения целевых групп приоритетного снижения смертности от новообразований в РФ проведена оценка потерянных лет продолжительности жизни в результате преждевременной смертности в виде показателя e† (e-dagger). Анализируемый период исследования – 2010–2019 гг.</p></sec><sec><title>Результаты</title><p>Результаты. Для Российской Федерации характерна наименьшая доля потерь от ЗНО в структуре потерь от всех причин смерти по сравнению с анализируемыми странами (Япония, Франция, Германия, Латвия, Литва, Эстония). Однако доля потерь интенсивно растет на протяжении 10 лет (в 2010 г. – 14,79 %, в 2019 г. – 17,54 %). В сравнении с анализируемыми странами для России в большей степени характерны потери от ЗНО в более молодом возрасте с наибольшим значением потерянных лет жизни в возрастной группе 60–64 года. Стандартизованное по возрасту число потерянных лет у мужчин в РФ на 67,1 % выше, чем у женщин. В возрастной группе от 25 до 49 лет потери ожидаемой продолжительности жизни от ЗНО у женщин выше и составляют 0,4 года (или 19 %) от всех потерь, что не характерно для других возрастных групп, в которых у мужчин потери превалируют. Выявлена значительная региональная дифференциация смертности в субъектах РФ, что также отражается в количестве потерянных лет.</p></sec><sec><title>Заключение</title><p>Заключение. Потенциал профилактических стратегий в РФ не реализован в полной мере – потери лет жизни в молодом и среднем возрасте требуют коррекции мероприятий по улучшению профилактической службы и онкологической помощи. Выявленная региональная дифференциация позволяет определить регионы с высокими потерями для первоочередных решений.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Burden of disease estimation allows analyses to be carried out integrally, including cause and effect assessment. the rate of life years lost due to premature mortality is part of the burden of disease analysis. given that the burden of cancer is steadily increasing, analysis of the number of years lost makes it possible to identify new strategic directions, as well as to adjust decisions already made, in the health care of cancer patients.</p></sec><sec><title>Purpose</title><p>Purpose: to estimate the loss of life expectancy as a result of premature mortality from cancer in the population of the Russian Federation.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. the analysis was carried out using international statistical databases for disease burden estimation, databases of the Federal state statistics service (Rosstat). to determine the target groups of priority reduction of mortality from neoplasms in the Russian Federation, an estimation of the lost years of life expectancy as a result of premature mortality in the form of the e† (e-dagger) indicator was carried out. the analyzed period of the study was 2010–2019.</p></sec><sec><title>Results</title><p>Results. the Russian Federation is characterized by the smallest share of losses from cancer in the structure of losses from all causes of death compared to the analyzed countries (Japan, France, germany, latvia, lithuania, estonia). However, the share of losses has been intensively increasing for 10 years (in 2010 – 14.79 %, in 2019 – 17.54 %). in comparison with the analyzed countries, Russia is more characterised by losses from cancer at a younger age, with the highest value of life years lost in the age group 60–64 years. the age-standardized number of years lost in men in Russia is 67.1 % higher than in women. in the age group from 25 to 49 years of age, the loss of life expectancy due to cancer in women is higher and accounts for 0.4 years (or 19 %) of all losses, which is not typical of other age groups in which losses in men prevail. A significant regional differentiation of mortality in the constituent entities of the Russian Federation has been revealed, which is also reflected in the number of years lost.</p></sec><sec><title>Conclusion</title><p>Conclusion. the potential of preventive strategies in the Russian Federation has not been fully realized – the loss of life years in young and middle age requires the correction of measures to improve preventive services and oncological care. the revealed regional differentiation allows us to identify regions with high losses for priority solutions.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>бремя онкологических заболеваний</kwd><kwd>потерянные годы жизни</kwd><kwd>ПГЖ</kwd><kwd>число потерянных лет жизни</kwd><kwd>злокачественные новообразования</kwd></kwd-group><kwd-group xml:lang="en"><kwd>burden of oncological diseases</kwd><kwd>years of life lost</kwd><kwd>Pgy</kwd><kwd>number of years of life lost</kwd><kwd>malignant</kwd></kwd-group><funding-group><funding-statement xml:lang="en">Funding This study required no funding</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Состояние онкологической помощи населению России в 2021 г. 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