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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-288</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>КАРЦИНОСАРКОМА ЩИТОВИДНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>THYROID CARCINOSARCOMA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перельмутер</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Perelmuter</surname><given-names>V. М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>634050, г. Томск, пер. Кооперативный 5</p></bio><bio xml:lang="en"><p>5, Kooperativny Street, 634050-Tomsk</p></bio><email xlink:type="simple">kulbakin_d@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глущенко</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Glushchenko</surname><given-names>S. А.</given-names></name></name-alternatives><email xlink:type="simple">kulbakin_d@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyev</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">kulbakin_d@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чойнзонов</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Choinzonov</surname><given-names>Е. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>634050, г. Томск, пер. Кооперативный 5</p></bio><bio xml:lang="en"><p>5, Kooperativny Street, 634050-Tomsk</p></bio><email xlink:type="simple">kulbakin_d@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мухамедов</surname><given-names>М. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Mukhamedov</surname><given-names>М. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>634050, г. Томск, пер. Кооперативный 5</p></bio><bio xml:lang="en"><p>5, Kooperativny Street, 634050-Tomsk</p></bio><email xlink:type="simple">kulbakin_d@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кульбакин</surname><given-names>Д. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulbakin</surname><given-names>D. Е.</given-names></name></name-alternatives><email xlink:type="simple">kulbakin_d@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Томский НИИ онкологии&#13;
&#13;
Сибирский государственный медицинский университет, г. Томск3</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk Cancer Research Institute&#13;
&#13;
Siberian State Medical University, Tomsk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Томский НИИ онкологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk Cancer Research Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Томский НИИ онкологии&#13;
&#13;
Сибирский государственный медицинский университет, г. Томск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk Cancer Research Institute&#13;
&#13;
Siberian State Medical University, Tomsk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Томский НИИ онкологии&#13;
&#13;
Национальный исследовательский Томский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk Cancer Research Institute&#13;
&#13;
National Research Tomsk Polytechnic University, Tomsk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2016</year></pub-date><volume>0</volume><issue>6</issue><fpage>60</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Перельмутер В.М., Глущенко С.А., Васильев Н.В., Чойнзонов Е.Л., Мухамедов М.Р., Кульбакин Д.Е., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Перельмутер В.М., Глущенко С.А., Васильев Н.В., Чойнзонов Е.Л., Мухамедов М.Р., Кульбакин Д.Е.</copyright-holder><copyright-holder xml:lang="en">Perelmuter V.М., Glushchenko S.А., Vasilyev N.V., Choinzonov Е.L., Mukhamedov М.R., Kulbakin D.Е.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/288">https://www.siboncoj.ru/jour/article/view/288</self-uri><abstract><p>Представлен редкий клинический случай карциносаркомы щитовидной железы. Описаны особенности клинического течения и диагностики, морфологической картины, прогрессирования и вариантов метастазирования этого гистотипа опухолей. Анализируются основные причины неблагоприятного течения карциносаркомы щитовидной железы.</p></abstract><trans-abstract xml:lang="en"><p>A rare case of thyroid carcinosarcoma has been presented. Clinical features of progression of this rare disease have been described. The detailed assessment of the histological pattern of metastatic spread of thyroid carcinocarcoma has been given. The main causes of unfavorable outcome of this disease have been analyzed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>карциносаркома щитовидной железы</kwd><kwd>лечение</kwd><kwd>морфологическая диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thyroid carcinosarcoma</kwd><kwd>treatment</kwd><kwd>histological diagnosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Иммуногистохимические методы: Руководство / Ed. G.L. Kumar, L. Rudberck: DAKO / Пер. с англ. под ред. Г.А. Франка, П.Г. Малькова. M., 2011. 224 с.</mixed-citation><mixed-citation xml:lang="en">Immunohistochemical methods: Manual/ Ed. G.L. Kumar, L. Rudberck: DAKO / Translation from English edited by G.A. Frank, P.G. Mal’kov. M., 2011. 224 p. 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