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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2016-15-2-107-112</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-340</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>НЕСОСТОЯТЕЛЬНОСТЬ ШВОВ КОЛОРЕКТАЛЬНОГО АНАСТОМОЗА (ОБЗОР ЛИТЕРАТУРЫ)</article-title><trans-title-group xml:lang="en"><trans-title>COLORECRAL ANASTOMOSIS FAILURE (LITERATURE REVIEW)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахметзянов</surname><given-names>Ф. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhmetzyanov</surname><given-names>F. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, заведующий кафедрой онкологии, лучевой диагностики и лучевой терапии, ГБОУ ВПО «Казанский государственный медицинский университет» (г. Казань, Российская Федерация). SPIN-код: 8908-4761.</p></bio><bio xml:lang="en"><p>MD, PhD, Head of Department of Oncology, Radiation Therapy and Diagnostic Imaging, Kazan State Medical University (Kazan, Russian Federation). SPIN-code: 8908-4761.</p></bio><email xlink:type="simple">akhmetzyanov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егоров</surname><given-names>В. И</given-names></name><name name-style="western" xml:lang="en"><surname>Egorov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры онкологии, лучевой диагностики и лучевой терапии, ГБОУ ВПО «Казанский государственный медицинский университет» (г. Казань, Российская Федерация). SPIN-код: 7794-4210.</p></bio><bio xml:lang="en"><p>Postgraduate, Department of Oncology, Radiation Therapy and Diagnostic Imaging, Kazan State Medical University (Kazan, Russian Federation). SPIN-код: 7794-4210.</p></bio><email xlink:type="simple">drvasiliy21@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Казанский государственный медицинский университет» Министерства здравоохранения Российской Федерации, 420012, г. Казань, ул. Бутлерова, 49;&#13;
ГАУЗ «Республиканский клинический онкологический диспансер» Министерства здравоохранения Республики Татарстан, г. Казань</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical University, 49, Butlerov Street, 420012-Kazan;&#13;
Republic Clinical Cancer Center, the Republic of Tatarstan2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБОУ ВПО «Казанский государственный медицинский университет» Министерства здравоохранения Российской Федерации, 420012, г. Казань, ул. Бутлерова, 49</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical University, 49, Butlerov Street, 420012-Kazan;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>15</day><month>07</month><year>2016</year></pub-date><volume>15</volume><issue>2</issue><fpage>107</fpage><lpage>112</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ахметзянов Ф.Ш., Егоров В.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Ахметзянов Ф.Ш., Егоров В.И.</copyright-holder><copyright-holder xml:lang="en">Akhmetzyanov F.S., Egorov V.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/340">https://www.siboncoj.ru/jour/article/view/340</self-uri><abstract><p>Одним из грозных осложнений после внутрибрюшной резекции прямой кишки является несостоятельность швов колоректального анастомоза, частота которой достигает до 40 %. Летальность при несостоятельности швов колоректального анастомоза может достигать до 39 %, а при расположении анастомоза в брюшной полости – более 90 %. В обзоре литературы показана актуальность проблемы несостоятельности швов колоректального анастомоза. Необходимы новые методы профилактики и лечения данного осложнения. Практически во всех исследованиях высота расположения опухоли и анастомоза от ануса является фактором риска развития несостоятельности швов колоректального анастомоза. По остальным факторам однозначного вывода нет.</p></abstract><trans-abstract xml:lang="en"><p>Colorectal anastomosis failure is one of the serious complications following abdominoperineal resection of the rectum, accounting for approximately 40 % of cases. Mortality rate in patients with colorectal anastomosis was reported to be 39 % and above 90 % in cases with anastomosis located in the abdomen. The literature analysis showed the importance of the problem of colorectal anastomosis failure, thus dictating the necessity of searching for the new methods of prevention and treatment for this serious complication. The aim of the study was to analyze the literature on the risk factors for colorectal anastomosis. The main factor influencing anastomotic leakage is the height of the anastomosis above the anal verge. The authors’ data were often contradictory.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>несостоятельность швов</kwd><kwd>колоректальный анастомоз</kwd><kwd>факторы риска</kwd><kwd>дренирование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>anastomotic leak</kwd><kwd>colorectal anastomosis</kwd><kwd>risk factors</kwd><kwd>drainage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Абелевич А.И., Комаров Д.В., Ларин А.А., Дезорцев И.Л., Паценкер E.H. Низкая передняя резекция прямой кишки // Хирургия. 2008. № 6. С. 63–66.</mixed-citation><mixed-citation xml:lang="en">Abelevich A.I., Komarov D.V., Larin A.A. Unresolved issues of low anterior resection of the rectum // Khirurgiya. 2008. № 6. P. 63–66. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Александров В.Б. Рак прямой кишки. М., 2001. 208 с.</mixed-citation><mixed-citation xml:lang="en">Aleksandrov V.B. Rectal cancer. M., 2001. 208 p. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Афанасьев С.Г., Старцева Ж.А., Тарасова А.С., Усова А.В., Самцов Е.Н. Результаты комбинированного лечения рака прямой кишки с применением пролонгированной предоперационной химиолучевой терапии // Сибирский онкологический журнал. 2012. № 6. С. 5–12.</mixed-citation><mixed-citation xml:lang="en">Afanasyev S.G., Startseva Zh.A., Tarasova A.S., Usova A.V., Samtsov E.N. Results of combined modality treatment including preoperative prolonged chemoradiotherapy for rectal cancer // Sibirskij onkologicheskij zhurnal. 2012. № 6. P. 5–12. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Ахметзянов Ф.Ш., Шайхутдинов Н.Т., Ахметзянова Ф.Ф., Валиев Н.А., Шемеунова З.Н., Егоров В.И. Аспирационное дренирование полости малого таза как способ консервативного лечения несостоятельности швов низкорасположенного колоректального анастомоза // Онкологическая колопроктология. 2015. № 1. С. 43–48.</mixed-citation><mixed-citation xml:lang="en">Akhmetzyanov F.Sh., Shaykhutdinov N.T., Akhmetzyanova F.F., Valiev N.A., Shemeunova Z.N., Egorov V.I. Suction drainage of the pelvic cavity as a method of conservative treatment of low-lying insolvency seams colorectal anastomosis // Onkologicheskaja koloproktologija. 2015. № 1. P. 43–48. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ахметзянов Ф.Ш., Шайхутдинов Н.Т., Валиев Н.А., Шемеунова З.Н., Егоров В.И. Аспирационное дренирование в профилактике послеоперационных гнойных осложнений при брюшно-анальной резекции прямой кишки // Казанский медицинский журнал. 2015. Т. 96, № 6. С. 935–939.</mixed-citation><mixed-citation xml:lang="en">Akhmetzyanov F.Sh., Shaykhutdinov N.T., Akhmetzyanova F.F., Valiev N.A., Shemeunova Z.N., Egorov V.I. Suction drainage in the prevention of postoperative septic complications of abdominal-anal resection of the rectum // Kazanskij medicinskij zhurnal. 2015. Vol. 96 (6). P. 935–939. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Ахметзянов Ф.Ш., Егоров В.И., Шайхутдинов Н.Т., Стрункин В.В., Рувинский Д.М., Ахметзянова Ф.Ф. Аспирационное забрюшинное дренирование полости малого таза как способ консервативного лечения несостоятельности швов «низкого» колоректального анастомоза // Поволжский онкологический вестник. 2015. № 4. С. 10–16.</mixed-citation><mixed-citation xml:lang="en">Akhmetzyanov F.Sh., Egorov V.I. Shaykhutdinov N.T. Suction drainage of retroperitoneal pelvic cavity as a method of conservative treatment of insolvency seams “low” colorectal anastomosis // Povolzhskiy onkologicheskiy vestnik. 2015. № 4. P. 10–20. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ахметзянов Ф.Ш., Егоров В.И., Шайхутдинов Н.Т., Ахметзянова Ф.Ф., Ахметзянова А.Ф. Дренирование полости малого таза через забрюшинное пространство при операциях на органах малого таза // Российский онкологический журнал. 2015. Т. 20, № 5. С. 22–27.</mixed-citation><mixed-citation xml:lang="en">Akhmetzyanov F.Sh., Egorov V.I., Shaykhutdinov N.T. Drainage of the pelvic cavity through the retroperitoneal space during operations on the pelvic organs // Rossiyskiy onkologicheskiy zhurnal. 2015. Vol. 20 (5). P. 22–27. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Бутенко А.В., Разбирин В.Н. Рак прямой кишки. Современные направления и тенденции в лечении (обзор литературы) // Сибирский онкологический журнал. 2011. № 6. С. 83–89.</mixed-citation><mixed-citation xml:lang="en">Vasil’ev S.V., Popov D.E., Grigoryan V.V. Preventive intestinal stoma surgery in colorectal cancer // Mater. Nauch.-prakt. konf.sMezhdunar. uchastiem «Dostizheniya i perspektivy reabilitatsii v koloproktologii». SPb., 2007. P. 54–55. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Васильев С.В., Григорян В.В., Ем А.Е., Седнев А.В., Васильев А.С. Применение проективной илеостомии в хирургическом лечении рака прямой кишки // Актуальные проблемы колопроктологии. Тезисы докладов научной конференции с международным участием. М., 2005. С. 176–177.</mixed-citation><mixed-citation xml:lang="en">Butenko А.V., Razbirin V.N. Rectal cancer. current trends in the management of rectal cancer (literature review) // Sibirskij onkologicheskij zhurnal. 2011. № 6. P. 83–89. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Воробьев Г.И., Севостьянов С.И., Чернышов С.В. Выбор оптимального вида превентивной кишечной стомы // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2007. Т. 17, № 2. С. 69–74.</mixed-citation><mixed-citation xml:lang="en">Vorob’ev G.I., Sevost’yanov S.I., Chernyshov S.V. Choosing the best type of prevention of intestinal stoma // Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2007. Vol. 17 (2). P. 69–74. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Грошилин В.С., Султанмурадов М.И., Харагезов А.Д., Хоронько Р.Ю. Патент РФ на изобретение № 2523822. Способ послеоперационной профилактики несостоятельности толсто-толстокишечного анастомоза. 2014 г.</mixed-citation><mixed-citation xml:lang="en">Groshilin V.S., Sultanmuradov M.I., Kharagezov A.D., Khoron’ko R.Yu. Patent RF № 2523822. A method of preventing postoperative insolvency thick-colonic anastomosis. 2014. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ем А.Е., Васильев С.В., Григорян В.В., Попов Д.Е. Применение превентивных кишечных стом в хирургическом лечении рака прямой кишки // Вопросы онкологии. 2007. № 4. С. 484–486.</mixed-citation><mixed-citation xml:lang="en">Em A.E., Vasil’ev S.V., Grigoryan V.V., Popov D.E. The use of preventive intestinal stomas in the surgical treatment of rectal cancer // Voprosy onkologii. 2007. № 4. P. 484–486. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ермаков Д.Ф. Факторы риска несостоятельности аппаратного анастомоза после передней резекции прямой кишки: Дис. … канд. мед. наук. М., 2012.</mixed-citation><mixed-citation xml:lang="en">Ermakov D.F. Risk factors for failure of hardware anastomosis after anterior resection of the rectum: Dis. … kand. med. nauk. M., 2012. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Одарюк Т.С. Хирургия рака прямой кишки. М., 2005. 255 с.</mixed-citation><mixed-citation xml:lang="en">Odaryuk T.S. Surgery for rectal cancer. M., 2005. 255 p. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Татарин В.С. Гнойные осложнения сфинктеросохраняющих операций у больных раком прямой кишки (диагностика, лечение, профилактика): Дис. … канд. мед. наук. М., 2007.</mixed-citation><mixed-citation xml:lang="en">Tatarin V.S. Suppurative complications sfinkterosohranyayuschih surgery in patients with rectal cancer (diagnosis, treatment, prevention): Вis. … kand. med. nauk. M., 2007. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Клиническая оперативная колопроктология: руководство для врачей / Под ред. В.Д. Федорова, Г.И. Воробьева, В.Л. Ривкина. М., 994. 432 с.</mixed-citation><mixed-citation xml:lang="en">Operational proctology: A Guide for Physicians / Ed. by V.D. Fedorov, G.I. Vorob’ev, V.L. Rivkin. M., 1994. 432 p. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ханевич М.Д., Шашолин М.А., Зязин А.А. Колоректальный рак: подготовка толстой кишки к операции. М.; Петрозаводск, 2003. 136 с.</mixed-citation><mixed-citation xml:lang="en">Hanevich M.D., Shasholin M.A., Zjazin A.A. Colorectal cancer: the preparation of the colon for surgery. M.; Petrozavodsk, 2003. 136 p. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Хожаев А.А. Тотальная мезоректумэктомия в органосохраняющей хирургии рака прямой кишки (Экспериментально-клиническое исследование) // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2008. Т. 18, № 1. С. 56–58.</mixed-citation><mixed-citation xml:lang="en">Khozhaev A.A. Total mezorektumektomiya-sparing surgery in colorectal cancer (experimentally-clinical research) // Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2008. Vol. 18 (1). P. 52–55. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Холдин С.А. Новообразования прямой и сигмовидной кишки. М., 1977. 504 с.</mixed-citation><mixed-citation xml:lang="en">Holdin S.A. Neoplasms rectum and sigmoid. M., 1977. 504 p. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Царьков П.В., Кравченко А.Ю., Тулина И.А., Цугуля П.Б. Всегда ли формирование аппаратного анастомоза при передней резекции гарантирует восстановление непрерывности кишечника? // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2012. Т. 22, № 4. С. 73–80.</mixed-citation><mixed-citation xml:lang="en">Tsar’kov P.V., Kravchenko A.Yu., Tulina I.A., Tsugulya P.B. Is it always the formation of hardware at the anastomosis anterior resection recovery ensures the continuity of the bowel? // Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2012. Vol. 22 (4). P. 63–80. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Шатрова Н.А. Прогнозирование, профилактика и лечение несостоятельности толстокишечных анастомозов: Дис. … канд. мед. наук. Пермь, 2012.</mixed-citation><mixed-citation xml:lang="en">Shatrova N.A. Prediction, prevention and treatment of colonic anastomoses insolvency: Dis. … kand. med. nauk. Perm’, 2012. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Asteria C.R., Gagliardi G., Pucciarelli S., Romano G., Infantino A., La Torre F., Tonelli F., Martin F., Pulica C., Ripetti V., Diana G., Amicucci G., Carlini M., Sommariva A., Vinciguerra G., Poddie D.B., Amato A., Bassi R., Galleano R., Veronese E., Mancini S., Pescio G., Occelli G.L., Bracchitta S., Castagnola M., Pontillo T., Cimmino G., Prati U., Vincenti R. Anastomotic leaks after anterior resection for mid and low rectal cancer: survey of the Italian of Colorectal Surgery // Tech. Сoloproctol. 2008. Vol. 12 (2). P. 103–110. doi: 10.1007/s10151-008-0407-9.</mixed-citation><mixed-citation xml:lang="en">Asteria C.R., Gagliardi G., Pucciarelli S., Romano G., Infantino A., La Torre F., Tonelli F., Martin F., Pulica C., Ripetti V., Diana G., Amicucci G., Carlini M., Sommariva A., Vinciguerra G., Poddie D.B., Amato A., Bassi R., Galleano R., Veronese E., Mancini S., Pescio G., Occelli G.L., Bracchitta S., Castagnola M., Pontillo T., Cimmino G., Prati U., Vincenti R. Anastomotic leaks after anterior resection for mid and low rectal cancer: survey of the Italian of Colorectal Surgery // Tech. Сoloproctol. 2008. Vol. 12 (2). P. 103–110. doi: 10.1007/s10151-008-0407-9.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Aytac E., Lavery I.C., Kalady M.F., Kiran R.P. Impact of obesity on operation performed, complications, and long-term outcomes in terms of restoration of intestinal continuity for patients with mid and low rectal cancer // Dis. Colon. Rectum. 2013. Vol. 56 (6). P. 689–697. doi: 10.1097/DCR.0b013e3182880ffa.</mixed-citation><mixed-citation xml:lang="en">Aytac E., Lavery I.C., Kalady M.F., Kiran R.P. Impact of obesity on operation performed, complications, and long-term outcomes in terms of restoration of intestinal continuity for patients with mid and low rectal cancer // Dis. Colon. Rectum. 2013. Vol. 56 (6). P. 689–697. doi: 10.1097/DCR.0b013e3182880ffa.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Carus T., Dammer R. Laparoscop fluorescence angiography with indocyanine green to control the perfusion of colorectal anastomoses intraoperatively // Surg. Technol. Int. 2012 Vol. 22. P. 27–32.</mixed-citation><mixed-citation xml:lang="en">Carus T., Dammer R. Laparoscop fluorescence angiography with indocyanine green to control the perfusion of colorectal anastomoses intraoperatively // Surg. Technol. Int. 2012 Vol. 22. P. 27–32.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Caulfield H., Hyman N.H. Anastomotic Leak After Low Anterior Resection. A Spectrum of Clinical Entities // JAMA Surg. 2013. Vol. 148 (2). P. 177–182. doi: 10.1001/jamasurgery.2013.413.</mixed-citation><mixed-citation xml:lang="en">Caulfield H., Hyman N.H. Anastomotic Leak After Low Anterior Resection. A Spectrum of Clinical Entities // JAMA Surg. 2013. Vol. 148 (2). P. 177–182. doi: 10.1001/jamasurgery.2013.413.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Center M., Siegel R., Jemal A. Global Cancer Facts &amp; Figures 2010 // Amer. Cancer Society. 2011. 58 p.</mixed-citation><mixed-citation xml:lang="en">Center M., Siegel R., Jemal A. Global Cancer Facts &amp; Figures 2010 // Amer. Cancer Society. 2011. 58 p.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Garlipp B., Ptok H., Schmidt U., Meyer F., Gastinger I., Lippert H. Neoadjuvant chemoradiotherapy for rectal carcinoma: effects on anastomotic leak rate and postoperative bladder dysfunction after nonemergency sphincter-preserving anterior rectal resection. Results of the Quality Assurance in Rectal Cancer Surgery multicenter observational trial // Langenbecks Arch Surg. 2010. Vol. 395 (8). P. 1031–1038. doi: 10.1007/s00423-010-0708-0.</mixed-citation><mixed-citation xml:lang="en">Garlipp B., Ptok H., Schmidt U., Meyer F., Gastinger I., Lippert H. Neoadjuvant chemoradiotherapy for rectal carcinoma: effects on anastomotic leak rate and postoperative bladder dysfunction after nonemergency sphincter-preserving anterior rectal resection. Results of the Quality Assurance in Rectal Cancer Surgery multicenter observational trial // Langenbecks Arch Surg. 2010. Vol. 395 (8). P. 1031–1038. doi: 10.1007/s00423-010-0708-0.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Guenaga K.F., Matos D., Wille-Jørgensen P. Mechanical bowel preparation for elective colorectal surgery // Cochrane Database Syst. Rev. 2011. Vol. 7 (9): CD001544. doi: 10.1002/14651858.CD001544.pub4.</mixed-citation><mixed-citation xml:lang="en">Guenaga K.F., Matos D., Wille-Jørgensen P. Mechanical bowel preparation for elective colorectal surgery // Cochrane Database Syst. Rev. 2011. Vol. 7 (9): CD001544. doi: 10.1002/14651858.CD001544.pub4.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Hojo К., Kojama Y., Моriуа Y. Lymphatic spread and its prognostic value in patients with rectal cancer // Amer. J. Surg. 1982. Vol. 144 (3). P. 350–354.</mixed-citation><mixed-citation xml:lang="en">Hojo К., Kojama Y., Моriуа Y. Lymphatic spread and its prognostic value in patients with rectal cancer // Amer. J. Surg. 1982. Vol. 144 (3). P. 350–354.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Huh J.W., Kim H.R., Kim Y.J. Anastomotic leakage after laparoscopic resection of rectal cancer: the impact of fibrin glue // Am J. Surg. 2010. Vol. 199 (4). P. 435–441. doi: 10.1016/j.amjsurg.2009.01.018.</mixed-citation><mixed-citation xml:lang="en">Huh J.W., Kim H.R., Kim Y.J. Anastomotic leakage after laparoscopic resection of rectal cancer: the impact of fibrin glue // Am J. Surg. 2010. Vol. 199 (4). P. 435–441. doi: 10.1016/j.amjsurg.2009.01.018.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Jafari M.D., Lee K.H., Halabi W.J., Mills S.D., Carmichael J.C., Stamos M.J., Pigazzi A. The use of indocyanine green fluorescence to assess anastomotic perfusion during robotic assisted laparoscopic rectal surgery // Surg. Endosc. 2013. Vol. 27 (8). P. 3003–3008. doi: 10.1007/s00464-013-2832-8.</mixed-citation><mixed-citation xml:lang="en">Jafari M.D., Lee K.H., Halabi W.J., Mills S.D., Carmichael J.C., Stamos M.J., Pigazzi A. The use of indocyanine green fluorescence to assess anastomotic perfusion during robotic assisted laparoscopic rectal surgery // Surg. Endosc. 2013. Vol. 27 (8). P. 3003–3008. doi: 10.1007/s00464-013-2832-8.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Kang C.Y., Halabi W.J., Chaudhry O.O., Nguyen V., Pigazzi A., Carmichael J.C., Mills S., Stamos M.J. Risk Factors for Anastomotic Leakage After Anterior Resection for Rectal Cancer // JAMA Surg. 2013. Vol. 148 (1). P. 65–71. doi: 10.1001/2013.jamasurg.2.</mixed-citation><mixed-citation xml:lang="en">Kang C.Y., Halabi W.J., Chaudhry O.O., Nguyen V., Pigazzi A., Carmichael J.C., Mills S., Stamos M.J. Risk Factors for Anastomotic Leakage After Anterior Resection for Rectal Cancer // JAMA Surg. 2013. Vol. 148 (1). P. 65–71. doi: 10.1001/2013.jamasurg.2.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Kim M.J., Shin R., Oh H.K., Park J.W., Jeong S.Y., Park J.G. The impact of heavy smoking on anastomotic leakage and stric-ture after low anterior resection in rectal cancer patients // World J. Surg. 2011. Vol. 35 (12). P. 2806–2810. doi: 10.1007/s00268-011-1286-1.</mixed-citation><mixed-citation xml:lang="en">Kim M.J., Shin R., Oh H.K., Park J.W., Jeong S.Y., Park J.G. The impact of heavy smoking on anastomotic leakage and stric-ture after low anterior resection in rectal cancer patients // World J. Surg. 2011. Vol. 35 (12). P. 2806–2810. doi: 10.1007/s00268-011-1286-1.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Kudszus S., Roesel C., Schachtrupp A., Höer J.J. Intraoperative laser fluorescence angiography in colorectal surgery: a noninvasive analysis to reduce the rate of anastomotic leakage // Langenbecks Arch. Surg. 2010. Vol. 395 (8). P. 1025–1030. doi: 10.1007/s00423-010-0699-x.</mixed-citation><mixed-citation xml:lang="en">Kudszus S., Roesel C., Schachtrupp A., Höer J.J. Intraoperative laser fluorescence angiography in colorectal surgery: a noninvasive analysis to reduce the rate of anastomotic leakage // Langenbecks Arch. Surg. 2010. Vol. 395 (8). P. 1025–1030. doi: 10.1007/s00423-010-0699-x.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Lee M.R., Hong C.W., Yoon S.N., Lim S.B., Park K.J., Park J.G. Risk factors for anastomotic leakage after resection for rectal cancer // Hepatogastroenterology. 2006. Vol. 53 (71). Р. 682–686.</mixed-citation><mixed-citation xml:lang="en">Lee M.R., Hong C.W., Yoon S.N., Lim S.B., Park K.J., Park J.G. Risk factors for anastomotic leakage after resection for rectal cancer // Hepatogastroenterology. 2006. Vol. 53 (71). Р. 682–686.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Lim M., Akhtar S., Sasapu K., Harris K., Burke D., Sagar P., Finan P. Clinicaland subclinical leaks after low colorectal anastomosis: a clinical and radiologic study // Dis. Colon Rectum. 2006. Vol. 49 (10). Р. 1611–1619.</mixed-citation><mixed-citation xml:lang="en">Lim M., Akhtar S., Sasapu K., Harris K., Burke D., Sagar P., Finan P. Clinicaland subclinical leaks after low colorectal anastomosis: a clinical and radiologic study // Dis. Colon Rectum. 2006. Vol. 49 (10). Р. 1611–1619.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Neutzling C.B., Lustosa S.A., Proenca I.M., da Silva E.M., Matos D. Stapled versus handsewn methods for colorectal anastomosis surgery // Cochrane Database Syst. Rev. 2012. 2: CD003144. doi: 10.1002/14651858.CD003144.pub2.</mixed-citation><mixed-citation xml:lang="en">Neutzling C.B., Lustosa S.A., Proenca I.M., da Silva E.M., Matos D. Stapled versus handsewn methods for colorectal anastomosis surgery // Cochrane Database Syst. Rev. 2012. 2: CD003144. doi: 10.1002/14651858.CD003144.pub2.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Pakkastie T.E., Luukkonen P.E., Järvinen H.J. Anastomotic leakage after anterior resection of the rectum // Eur. J. Surg. 1994. Vol. 160 (5). Р. 293–297.</mixed-citation><mixed-citation xml:lang="en">Pakkastie T.E., Luukkonen P.E., Järvinen H.J. Anastomotic leakage after anterior resection of the rectum // Eur. J. Surg. 1994. Vol. 160 (5). Р. 293–297.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Parker M.C., Pohlen U., Borel Rinkes I.H., Delvin T. The application of TachoSil® for sealing colorectal anastomosis: a feasibility study // Colorectal Dis. 2013. Vol. 15 (2). P. 252–257. doi: 10.1111/j.1463-1318.2012.03144.x.</mixed-citation><mixed-citation xml:lang="en">Parker M.C., Pohlen U., Borel Rinkes I.H., Delvin T. The application of TachoSil® for sealing colorectal anastomosis: a feasibility study // Colorectal Dis. 2013. Vol. 15 (2). P. 252–257. doi: 10.1111/j.1463-1318.2012.03144.x.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Polglase A.L., McMurrick P.J., Tremayne A.B., Bhathal P.S. Local Recurrence After Curative Anterior Resection with Principally Blunt Dissection for Carcinoma of the Rectum and Rectosigmoid // Dis Colon Rectum. 2001. Vol. 44 (7). P. 947–954.</mixed-citation><mixed-citation xml:lang="en">Polglase A.L., McMurrick P.J., Tremayne A.B., Bhathal P.S. Local Recurrence After Curative Anterior Resection with Principally Blunt Dissection for Carcinoma of the Rectum and Rectosigmoid // Dis Colon Rectum. 2001. Vol. 44 (7). P. 947–954.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Pommergaard H.C., Gessler B., Burcharth J., Angenete E., Haglind E., Rosenberg J. Preoperative risk factors for anastomotic leakage after resection for colorectal cancer: a systematic review and meta-analysis // Colorectal Dis. 2014. Vol. 16 (9). P. 662–671. doi: 10.1111/codi.12618.</mixed-citation><mixed-citation xml:lang="en">Pommergaard H.C., Gessler B., Burcharth J., Angenete E., Haglind E., Rosenberg J. Preoperative risk factors for anastomotic leakage after resection for colorectal cancer: a systematic review and meta-analysis // Colorectal Dis. 2014. Vol. 16 (9). P. 662–671. doi: 10.1111/codi.12618.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Taflampas P., Christodoulakis M., Tsiftsis D.D. Anastomotic Leakage After Low Anterior Resection for Rectal Cancer: Facts, Obscurity, and Fiction // Surg. Today. 2009. Vol. 39 (3). P. 183–188. doi: 10.1007/s00595-008-3835-2.</mixed-citation><mixed-citation xml:lang="en">Taflampas P., Christodoulakis M., Tsiftsis D.D. Anastomotic Leakage After Low Anterior Resection for Rectal Cancer: Facts, Obscurity, and Fiction // Surg. Today. 2009. Vol. 39 (3). P. 183–188. doi: 10.1007/s00595-008-3835-2.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Vakalopoulos K.A., Daams F., Wu Z., Timmermans L., Jeekel J.J., Kleinrensink G.J., van der Ham A., Lange J.F. Tissue adhesives in gastrointestinal anastomosis: a systematic // J. Surg. Res. 2013. Vol. 180 (2). P. 290–300. doi: 10.1016/j.jss.2012.12.043.</mixed-citation><mixed-citation xml:lang="en">Vakalopoulos K.A., Daams F., Wu Z., Timmermans L., Jeekel J.J., Kleinrensink G.J., van der Ham A., Lange J.F. Tissue adhesives in gastrointestinal anastomosis: a systematic // J. Surg. Res. 2013. Vol. 180 (2). P. 290–300. doi: 10.1016/j.jss.2012.12.043.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Warschkow R., Steffen T., Thierbach J., Bruckner T., Lange J., Tarantino I. Risk Factors for Anastomotic Leakage after Rectal Cancer Resection and Reconstruction with Colorectostomy. A Retrospective Study with Bootstrap Analysis // Ann. Surg. Oncol. 2011. Vol. 18 (10): P. 2772–2782. doi: 10.1245/s10434-011-1696-1.</mixed-citation><mixed-citation xml:lang="en">Warschkow R., Steffen T., Thierbach J., Bruckner T., Lange J., Tarantino I. Risk Factors for Anastomotic Leakage after Rectal Cancer Resection and Reconstruction with Colorectostomy. A Retrospective Study with Bootstrap Analysis // Ann. Surg. Oncol. 2011. Vol. 18 (10): P. 2772–2782. doi: 10.1245/s10434-011-1696-1.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Weaver M., Burdon D.W., Youngs D.J., Keighley M.R. Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery // Am. J. Surg. 1986. Vol. 151 (4). P. 437–442.</mixed-citation><mixed-citation xml:lang="en">Weaver M., Burdon D.W., Youngs D.J., Keighley M.R. Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery // Am. J. Surg. 1986. Vol. 151 (4). P. 437–442.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Williams N.S., Nasmyth D.G., Jones D., Smith A.H. De-functioning stomas: a prospective controlled trial comparing loop ileostomy with loop transverse colostomy // Br. J. Surg. 1986. Vol. 73 (7). P. 566–570.</mixed-citation><mixed-citation xml:lang="en">Williams N.S., Nasmyth D.G., Jones D., Smith A.H. De-functioning stomas: a prospective controlled trial comparing loop ileostomy with loop transverse colostomy // Br. J. Surg. 1986. Vol. 73 (7). P. 566–570.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Xiao L., Zhang W.B., Jiang P.C., Bu X.F., Yan Q., Li H., Zhang Y.J., Yu F. Can transanal tube placement after anterior resection for rectal carcinoma reduce anastomotic leakage rate? A single-institution prospective randomized study // World J. Surg. 2011. Vol. 35 (6). P. 1367–1377. doi: 10.1007/s00268-011-1053-3.</mixed-citation><mixed-citation xml:lang="en">Xiao L., Zhang W.B., Jiang P.C., Bu X.F., Yan Q., Li H., Zhang Y.J., Yu F. Can transanal tube placement after anterior resection for rectal carcinoma reduce anastomotic leakage rate? A single-institution prospective randomized study // World J. Surg. 2011. Vol. 35 (6). P. 1367–1377. doi: 10.1007/s00268-011-1053-3.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Yang L., Huang X.E., Zhou J.N. Risk Assessment on Anastomotic Leakage after Rectal Cancer Surgery: An Analysis of 753 Patients // Asian Pac J. Cancer Prev. 2013. 14 (7). P. 4447–4453.</mixed-citation><mixed-citation xml:lang="en">Yang L., Huang X.E., Zhou J.N. Risk Assessment on Anastomotic Leakage after Rectal Cancer Surgery: An Analysis of 753 Patients // Asian Pac J. Cancer Prev. 2013. 14 (7). P. 4447–4453.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Zaharie F., Mocan L., Tomuş C., Mocan T., Zaharie R., Bartoş D., Bartoş A., Vlad L., Iancu C. Risk factors for anastomotic leakage following colorectal resection for cancer // Chirurgia (Bucur). 2012. Vol. 107 (1). P. 27–32.</mixed-citation><mixed-citation xml:lang="en">Zaharie F., Mocan L., Tomuş C., Mocan T., Zaharie R., Bartoş D., Bartoş A., Vlad L., Iancu C. Risk factors for anastomotic leakage following colorectal resection for cancer // Chirurgia (Bucur). 2012. Vol. 107 (1). P. 27–32.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao W.T., Hu F.L., Li Y.Y., Li H.J., Luo W.M., Sun F. Use of a transanal drainage tube for prevention of anastomotic leakage and bleeding after anterior resection for rectal cancer // World J. Surg. 2013. Vol. 37 (1). P. 227–232. doi: 10.1007/s00268-012-1812-9.</mixed-citation><mixed-citation xml:lang="en">Zhao W.T., Hu F.L., Li Y.Y., Li H.J., Luo W.M., Sun F. Use of a transanal drainage tube for prevention of anastomotic leakage and bleeding after anterior resection for rectal cancer // World J. Surg. 2013. Vol. 37 (1). P. 227–232. doi: 10.1007/s00268-012-1812-9.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
