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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2016-15-3-28-36</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-346</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Мини-инвазивная хирургия колоректального рака у больных старческого возраста</article-title><trans-title-group xml:lang="en"><trans-title>MINIMALLY-INVASIVE SURGERY FOR COLLORECTAL CANCER IN ELDERLY PATIENTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черниковский</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernikovskiy</surname><given-names>I. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, заведующий колопроктологическим отделением</p></bio><bio xml:lang="en"><p>MD, PhD, Head of Coloproctological Department</p></bio><email xlink:type="simple">Odindra@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гельфонд</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Gelfond</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, заведующий отделением анестезиологии и реанимации</p></bio><bio xml:lang="en"><p>MD, PhD, Head of Anesthesiology and Resuscitation</p></bio><email xlink:type="simple">vladgelfond@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Загрядских</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zagryadskikh</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач отделения анестезиологии и реанимации</p></bio><bio xml:lang="en"><p>Physician of Department of Anesthesiology and Resuscitation</p></bio><email xlink:type="simple">Krepatura1@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савчук</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Savchuk</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студент 6-го курса факультета подготовки и усовершенствования гражданских врачей</p></bio><bio xml:lang="en"><p>Final-year Student of the Faculty of Training and Improvement of Civilian Doctors</p></bio><email xlink:type="simple">Savchuk-sergej@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский клинический научно-практический центр специализированных видов медицинской помощи (онкологический), г. Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St-Petrsburg Clinical Research and Practical Center of Specialized Types of Medical Care, St-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2016</year></pub-date><volume>15</volume><issue>3</issue><fpage>28</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Черниковский И.Л., Гельфонд В.М., Загрядских А.С., Савчук С.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Черниковский И.Л., Гельфонд В.М., Загрядских А.С., Савчук С.А.</copyright-holder><copyright-holder xml:lang="en">Chernikovskiy I.L., Gelfond V.M., Zagryadskikh A.S., Savchuk S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/346">https://www.siboncoj.ru/jour/article/view/346</self-uri><abstract><p>Введение. Возраст пациента является одним из основных факторов риска смерти от колоректального рака (КРР). Изучается место лапароскопических радикальных вмешательств в алгоритме лечения больных КРР пожилого и старческого возраста. Цель исследования - оценить опыт хирургического лечения больных КРР старческого возраста. Материал и методы. Представлены результаты резекций прямой и ободочной кишки у 106 больных колоректальным раком старше 75 лет, прооперированных в 2013-2015 гг., 66 больным операция выполнена лапаротомным доступом, 40 пациентам проведено эндовидеохирургическое вмешательство. Группы были сопоставимы по шкалам ASA, CR-PОSSUM, индексу массы тела и возрасту, стадии заболевания и виду операций. результаты. При лапароскопических операциях значимо меньше оказалась средняя продолжительность вмешательства - 127 мин, при «открытых» операциях - 146 мин. Интраоперационная кровопотеря была выше при лапаротомии - 167 против 109 мл, но различия не значимы (р=0,36). По качеству лимфодиссекции и адекватному объему резекции группы не отличались. Средний койко-день при лапароскопических операциях оказался несущественно меньшим (р=0,43). Осложнения встречались в обеих группах с одинаковой частотой - 13,6 % против 15,0 %, которая не превышала среднего показателя в других возрастных группах. Медиана наблюдения за больными составила 16 мес (6-30 мес). В отдаленные сроки после лечения умерло в 2 раза больше больных, оперированных «открытым» способом, однако различия не достигли статистической достоверности. выводы. Частота послеоперационных осложнений среди больных КРР старческого возраста не превышает средние показатели и не зависит от возраста. По объему интраоперационной кровопотери, радикальности вмешательства, качеству лимфодиссекции обе группы сопоставимы. Достоверно меньшая продолжительность лапароскопических операций объясняется более быстрым оперативным доступом, что, однако, не дает преимуществ в сокращении среднего койко-дня и снижении числа осложнений. Выбор оперативного доступа не влияет на качество жизни больных после лечения. Отмечена тенденция к увеличению доли смертей в отдаленном периоде от причин, не связанных с КРР, и, как следствие, снижению общей выживаемости среди пациентов старческого возраста, прооперированных лапаротомным доступом.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. The patient’s age is one of the major risk factors of death from colorectal cancer. The role of laparo- scopic radical surgeries in the treatment of colorectal cancer in elderly patients is being studied. The purpose of the study was to evaluate the experience of surgical treatment for elderly patients with colorectal cancer. material and methods. The treatment outcomes of 106 colorectal cancer patients aged 75 years or over, who underwent surgery between 2013 and 2015 were presented. Out of them, 66 patients underwent laparatomy and 40 patients underwent laparoscopy. Patients were matched for ASA and CR-PОSSUM scales, age-and body mass index, dis- ease stage and type of surgery. Results. The mean duration of surgery was significantly less for laparoscopy than for laparotomy (127 min versus 146 min). Intraoperative blood loss was higher in patients treated by laparotomy than by laparoscopy (167 ml versus 109 ml), but the differences were insignificant (р=0.36). No differences in lymphodissection quality and adequate resection volume between the groups were found. The average hospital stay was not significantly shorter in the laparoscopic group (р=0.43). Complications occurred with equal frequency in both groups (13.6 % compared to 15.0 %). The median follow-up time was 16 months (range, 6-30 months). The number of patients died during a long-term follow-up was 2 times higher after laparotomic surgery than after laparoscopic surgery, however, the difference was not statistically significant. Conclusion. Postoperative compli- cations in elderly patients with colorectal cancer did not exceed the average rates and did not depend on the age. Both groups were matched for the intraoperative bleeding volume and quality of lymphodenectomy. Significantly shorter duration of laparoscopic surgery was explained by the faster surgical access however, it showed no benefit in reducing the average length of hospital stay and decreasing the number of complications. The choice of surgi- cal access had no impact on life quality of patients after treatment. There was a tendency toward an increase in the percentage of deaths in a long-term follow-up due to causes not related to colorectal cancer, thus, resulting in the decreased overall survival rate in elderly patients treated by laparatomy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальный рак</kwd><kwd>больные пожилого возраста</kwd><kwd>хирургическое лечение</kwd><kwd>лапароскопические операции</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colorectal cancer</kwd><kwd>elderly patients</kwd><kwd>surgical treatment</kwd><kwd>laparoscopic surgery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Баранов Д.В., Крапивин Б.В., Фисун А.М. Применение лифтинговой методики выполнения ЛХЭ в лечении ЖКБ у больных пожилого и старческого возраста // Эндоскопическая хирургия. 1999. № 2. 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