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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2016-15-3-78-81</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-354</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОПЫТ РАБОТЫ ОНКОЛОГИЧЕСКИХ УЧРЕЖДЕНИЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ONCOLOGY PRACTICE</subject></subj-group></article-categories><title-group><article-title>СРАВНИТЕЛЬНАЯ ОЦЕНКА МЕТОДОВ ОБЕЗБОЛИВАНИЯ ПРИ ОПЕРАЦИЯХ В ОНКОГИНЕКОЛОГИИ</article-title><trans-title-group xml:lang="en"><trans-title>COMPARATIVE ASSESSMENT OF ANESTHESIA METHODS FOR GYNECOLOGIC SURGERY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хусаинова</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khusainova</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры анестезиологии и реаниматологии, медицины катастроф</p></bio><bio xml:lang="en"><p>Lecturer, Department of Anesthesiology and Intensive Care</p></bio><email xlink:type="simple">Ilyuzovich@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ ВПО МЗ РТ «Казанский государственный медицинский университет», ГАУЗ «Городская клиническая больница № 7»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical University, Municipal Clinical Hospital № 7</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>20</day><month>07</month><year>2016</year></pub-date><volume>15</volume><issue>3</issue><fpage>78</fpage><lpage>81</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хусаинова И.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Хусаинова И.И.</copyright-holder><copyright-holder xml:lang="en">Khusainova I.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/354">https://www.siboncoj.ru/jour/article/view/354</self-uri><abstract><p>Цель исследования - улучшение качества обезболивания при онкогинекологических операциях. Материал и методы. В исследование была включена 421 пациентка, которым были выполнены простые гистерэктомии. Больные были разделены на 3 группы в соответствии с применяемыми методами аналгезии. Во всех случаях применяли метод мультимодальной сбалансированной аналгезии. В 1-й группе дополнительно использовали продленную эпидуральную аналгезию, 2-я группа была контрольной, без продленной эпидуральной аналгезии. В 3-й группе накануне операции применяли адъювантный анальгетик габапентин в дозе 600 мг. результаты. Выявлено значительное различие интенсивности болевого синдрома в течение первых 72 ч после операции в зависимости от метода аналгезии. При применении методики эпидуральной аналгезии, контролируемой пациенткой, показано снижение интенсивности боли, уменьшение потребности в опиоидных аналгетиках в периоперационном периоде, а также снижение риска развития послеоперационной тошноты и рвоты отмечено при назначении габапентина.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of the study: to improve the quality of anesthesia for gynecologic cancer surgery. materials and methods. The study included 421 patients who underwent a routine hysterectomy. The patients were divided into 3 groups with respect to analgesic method. The method of multimodal balanced analgesia was used in all cases. Group I patients additionally received epidural analgesia. Group II patients did not receive epidural analgesia (the control group). Group III patients received 600 mg of gabapentin as an adjuvant to opioid analgesia. Results. A significant difference in pain intensity within the first 72 hours after surgery between 3 groups of patients was found. Oral gabapentin as an adjunct to patient-controlled epidural analgesia provided efficient pain relief, reduction in the need for opioid analgesics in the perioperative period, as well as reduction in the incidence of postoperative nausea and vomiting after surgery.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гистерэктомия</kwd><kwd>послеоперационная боль</kwd><kwd>мультимодальная эпидуральная аналгезия</kwd><kwd>габапентин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hysterectomy</kwd><kwd>postoperative pain</kwd><kwd>multimodal epidural analgesia</kwd><kwd>gabapentin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бохман Я.В. Руководство по онкогинекологии. М., 2012. 464 с.</mixed-citation><mixed-citation xml:lang="en">Bohman Ja.V. Guidance by oncogynecology. M., 2012. 464 p. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Голуб И.Е. Хирургический стресс и обезболивание. Иркутск, 2005. 201 с.</mixed-citation><mixed-citation xml:lang="en">Golub I.E. Surgical stress and pain relief. Irkutsk,, 2005. 201 p. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Кукушкин М.Л. Общая патология боли. Руководство для врачей. М., 2004. 140 с.</mixed-citation><mixed-citation xml:lang="en">Kukushkin M.L. General pathology of pain . Guidelines for physicians. M., 2004. 140 p. [in Russian]</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Chang C.Y., Challa C.K., Shan J., Eloy J.D. Gabapentin in acute pain management // Biomed. Res. Int. 2014:631756. doi: 10.1155/2014/631756.</mixed-citation><mixed-citation xml:lang="en">Chang C.Y., Challa C.K., Shan J., Eloy J.D. Gabapentin in acute pain management // Biomed. Res. Int. 2014:631756. doi: 10.1155/2014/631756.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Gerbershaden M.U., Aduckathil S., van Wijck A.J., Peelen L.M., Kalkman C.J., Meissner W. Pain intensity on the first day after surgery: A Prospective Cohort Study Comparing 179 Surgical Procedures // Anaesthesiology. 2013. Vol. 118 (4). P. 934-944. doi: 10.1097/ ALN.0b013e31828866b3.</mixed-citation><mixed-citation xml:lang="en">Gerbershaden M.U., Aduckathil S., van Wijck A.J., Peelen L.M., Kalkman C.J., Meissner W. Pain intensity on the first day after surgery: A Prospective Cohort Study Comparing 179 Surgical Procedures // Anaesthesiology. 2013. Vol. 118 (4). P. 934-944. doi: 10.1097/ ALN.0b013e31828866b3.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Griensven H., Strong J., Unruh A. Pain. A textbook for health professionals. 2nd Edition. Elsevier. Churchil Livingstone, 2014. 430 p.</mixed-citation><mixed-citation xml:lang="en">Griensven H., Strong J., Unruh A. Pain. A textbook for health professionals. 2nd Edition. Elsevier. Churchil Livingstone, 2014. 430 p.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Lim P.C., Crane J.T., English E.J., Farnam R.W., Garza D.M., Winter M.L., Rozeboom J.L. Multicenter analysis comparing robotic, open, laparoscopic, and vaginal hysterectomies performed by high-volume surgeons for bening indications // Int. J. Gynaecol. Obstet. 2016. Vol. 133 (3). P. 359–364. doi: 10.1016/j.ijdo.2015.11.010.</mixed-citation><mixed-citation xml:lang="en">Lim P.C., Crane J.T., English E.J., Farnam R.W., Garza D.M., Winter M.L., Rozeboom J.L. Multicenter analysis comparing robotic, open, laparoscopic, and vaginal hysterectomies performed by high-volume surgeons for bening  indications // Int. J. Gynaecol. Obstet. 2016. Vol. 133 (3). P. 359–364. doi: 10.1016/j.ijdo.2015.11.010.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Mamittz S., Kohler C. Current therapy of patients with endometrial carcinoma. A critical review // Strahlenther. Onkol. 2012. Vol. 188 (1). P. 12–20. Doi: 10.1007/s00066-011-0004-0.</mixed-citation><mixed-citation xml:lang="en">Mamittz S., Kohler C. Current therapy of patients with endometrial carcinoma. A critical review // Strahlenther. Onkol. 2012. Vol. 188 (1). P. 12–20. Doi: 10.1007/s00066-011-0004-0.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Postoperative pain management – good clinical practice. General recommendations and principles for successful pain management. General recommendations and principles for successful pain management. Produced with the consultations with the Europeans Society of Regional Anaesthesia and Pain Therapy / Eds. N. Rawal, J. Andres, B.J. Fischer. 2005, 57 p.</mixed-citation><mixed-citation xml:lang="en">Postoperative pain management – good clinical practice. General recommendations and principles for successful pain management. General recommendations and principles for successful pain management. Produced with the consultations with the Europeans Society of Regional Anaesthesia and Pain Therapy / Eds. N. Rawal, J. Andres, B.J. Fischer. 2005, 57 p.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
