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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2025-24-3-15-26</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-3660</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Сравнительный анализ хирургических доступов при выполнении поясничной лимфаденэктомии у больных раком эндометрия</article-title><trans-title-group xml:lang="en"><trans-title>Comparative analysis of surgical approaches for para-aortic lymphadenectomy in endometrial cancer patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6423-3917</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алимов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Alimov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алимов Владимир Александрович - кандидат медицинских наук, заведующий онкогинекологическим отделением № 70, Московский МНКЦ им. С.П. Боткина ДЗМ; ассистент кафедры акушерства и гинекологии, ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России.</p><p>125284, Москва, 2-й Боткинский пр-д, 5; 125993, Москва, ул. Баррикадная, 2/1</p></bio><bio xml:lang="en"><p>Vladimir A. Alimov - MD, PhD, Head of Gynecologic Oncology Department No. 70, S.P. Botkin Moscow MRCC; Assistant, Department of Obstetrics and Gynecology, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia.</p><p>5, 2nd Botkinsky proezd, Moscow, 125284; 2/1, Barrikadnaya St., Moscow, 125993</p></bio><email xlink:type="simple">alimovvladimirr@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2768-5698</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новикова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Novikova</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Новикова Елена Григорьевна - доктор медицинских наук, профессор, заведующая отделением гинекологии, МНОИ им. П.А. Герцена – филиал ФГБУ «НМИЦ Радиологии» Минздрава России; научный сотрудник, Московский МНКЦ им. С.П. Боткина ДЗМ.</p><p>125284, Москва, 2-й Боткинский пр-д, 5; 125284, Москва, 2-й Боткинский пр-д, 3</p></bio><bio xml:lang="en"><p>Elena G. Novikova - MD, DSc, Professor, Head of the Department of Gynecology, P.A. Herzen Medical and Research Institute – branch of National Medical Research Radiological Centre, Ministry of Health of Russia; Researcher, S.P. Botkin Moscow MRCC.</p><p>5, 2nd Botkinsky proezd, Moscow, 125284; 3, 2nd Botkinsky proezd, Moscow, 125284</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8391-1210</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Греков</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Grekov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Греков Дмитрий Николаевич - кандидат медицинских наук, заместитель директора по клинической работе – главный врач, хирург, онколог, Московский МНКЦ им. С.П. Боткина ДЗМ; доцент кафедры хирургии, ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России.</p></bio><bio xml:lang="en"><p>Dmitry N. Grekov - MD, PhD, Deputy Director for Clinical Work – Chief Physician, Surgeon, Oncologist, S.P. Botkin Moscow Multidisciplinary Research and Clinical Centre; Associate Professor, Department of Surgery, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia (Moscow, Russia). ORCID: 0000-0001-8391-1210.5, 2nd Botkinsky proezd, Moscow, 125284; 2/1, Barrikadnaya St., Moscow, 125993</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5366-1281</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедев Сергей Сергеевич - доктор медицинских наук, доцент, заместитель главного врача по онкологии, ведущий научный сотрудник, Московский МНКЦ им. С.П. Боткина ДЗМ; профессор кафедры хирургии, ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России.</p><p>125284, Москва, 2-й Боткинский пр-д, 5; 125993, Москва, ул. Баррикадная, 2/1</p></bio><bio xml:lang="en"><p>Sergey S. Lebedev, MD, DSc, Associate Professor, Deputy Chief Physician for Oncology, Leading Researcher, S.P. Botkin Moscow MRCC; Professor, Department of Surgery, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia.</p><p>5, 2nd Botkinsky proezd, Moscow, 125284; 2/1, Barrikadnaya St., Moscow, 125993</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5699-3695</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Багателия</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bagatelia</surname><given-names>Z. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Багателия Зураб Антонович - доктор медицинских наук, первый заместитель директора, Московский МНКЦ им. С.П. Боткина ДЗМ; профессор кафедры хирургии, ведущий научный сотрудник, хирург, онколог, ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России.</p><p>125284, Москва, 2-й Боткинский пр-д, 5; 125993, Москва, ул. Баррикадная, 2/1</p></bio><bio xml:lang="en"><p>Zurab A. Bagatelia - MD, DSc, First Deputy Director, S.P. Botkin Moscow MRCC; Professor, Department of Surgery, Leading Researcher, Surgeon, Oncologist, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia.</p><p>5, 2nd Botkinsky proezd, Moscow, 125284; 2/1, Barrikadnaya St., Moscow, 125993</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9762-6266</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полякова</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyakova</surname><given-names>N. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полякова Наталья Юрьевна - акушер-гинеколог онкогинекологического отделения № 70, Московский МНКЦ им. С.П. Боткина ДЗМ.</p><p>125284, Москва, 2-й Боткинский пр-д, 5</p></bio><bio xml:lang="en"><p>Natalia Yu. Polyakova - MD, Obstetrician-Gynecologist, Gynecologic Oncology Department.</p><p>5, 2nd Botkinsky proezd, Moscow, 125284</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5593-6549</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лаевская</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Laevskaya</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лаевская Анастасия Андреевна - ординатор 1-го года, Московский многопрофильный научно-клинический центр им. С.П. Боткина ДЗМ.</p><p>125284, Москва, 2-й Боткинский пр-д, 5</p></bio><bio xml:lang="en"><p>Anastasia A. Laevskaya - 1st year resident in Obstetrics and Gynecology.</p><p>5, 2nd Botkinsky proezd, Moscow, 125284</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4230-8033</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабунин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabunin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шабунин Алексей Васильевич - доктор медицинских наук, профессор, академик РАН, главный хирург и эндоскопист Департамента здравоохранения Москвы, директор, Московский МНКЦ им. С.П. Боткина ДЗМ; заведующий кафедрой хирургии, ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России.</p><p>125284, Москва, 2-й Боткинский пр-д, 5; 125993, Москва, ул. Баррикадная, 2/1</p></bio><bio xml:lang="en"><p>Alexey V. Shabunin - MD, DSc, Professor, Full Member of the Russian Academy of Sciences, Chief Surgeon and Endoscopist of the Moscow Department of Health Care, Director, S.P. Botkin Moscow MRCC; Head of the Department of Surgery, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia.</p><p>5, 2nd Botkinsky proezd, Moscow, 125284; 2/1, Barrikadnaya St., Moscow, 125993</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский многопрофильный научно-клинический центр им. С.П. Боткина ДЗМ; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.P. Botkin Moscow Multidisciplinary Research and Clinical Centre; Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский многопрофильный научно-клинический центр им. С.П. Боткина ДЗМ; МНОИ им. П. А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.P. Botkin Moscow Multidisciplinary Research and Clinical Centre; P.A. Herzen Medical and Research Institute – branch of National Medical Research Radiological Centre, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Московский многопрофильный научно-клинический центр им. С.П. Боткина ДЗМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.P. Botkin Moscow Multidisciplinary Research and Clinical Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>04</day><month>08</month><year>2025</year></pub-date><volume>24</volume><issue>3</issue><fpage>15</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алимов В.А., Новикова Е.Г., Греков Д.Н., Лебедев С.С., Багателия З.А., Полякова Н.Ю., Лаевская А.А., Шабунин А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Алимов В.А., Новикова Е.Г., Греков Д.Н., Лебедев С.С., Багателия З.А., Полякова Н.Ю., Лаевская А.А., Шабунин А.В.</copyright-holder><copyright-holder xml:lang="en">Alimov V.A., Novikova E.G., Grekov D.N., Lebedev S.S., Bagatelia Z.A., Polyakova N.Y., Laevskaya A.A., Shabunin A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/3660">https://www.siboncoj.ru/jour/article/view/3660</self-uri><abstract><sec><title>Введение</title><p>Введение. На данный момент роль лимфаденэктомии при первой стадии рака эндометрия (РЭ) отходит на второй план, уступая биопсии сторожевых лимфоузлов. С учетом новых данных об улучшении выживаемости у больных высокого риска лимфогенного метастазирования при проведении полноценной тазовой и поясничной лимфаденэктомии и тенденции к рестадированию данной когорты больных во вторую стадию в соответствии с новой классификацией FIGO 2023 проблема выполнения поясничной лимфаденэктомии вновь становится актуальной.</p><p>Цель исследования – сравнительный анализ используемых хирургических доступов при выполнении поясничной лимфаденэктомии у больных РЭ с акцентом на недостатки и преимущества каждого.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Ретроспективно произведен анализ историй болезни 122 пациенток, прооперированных в ММКНЦ им. С. П. Боткина по поводу рака эндометрия. В исследование включены пациентки, которым были выполнены хирургические вмешательства в объеме тазовой и поясничной лимфаденэктомии, гистерэктомии посредством четырех хирургических доступов: лапаротомного (n=28), лапароскопического трансабдоминального (n=30), лапароскопического забрюшинного (n=41) и робот-ассистированного забрюшинного (n=23). Проводился сравнительный анализ следующих показателей: индекса массы тела больных, длительности операции, количества удаленных тазовых и парааортальных лимфоузлов, частоты достижения III и IV уровней лимфодиссекции, частоты интраи послеоперационных осложнений, количества койкодней в послеоперационном периоде и частоты переводов в отделение реанимации и интенсивной терапии.</p></sec><sec><title>Результаты</title><p>Результаты. По сравнению с другими подгруппами хирургические вмешательства, проводимые посредством лапароскопического забрюшинного доступа, характеризовались наименьшей длительностью операции, высокой частотой достижений IV уровня лимфодиссекции и приемлемым уровнем интраи послеоперационных осложнений.</p></sec><sec><title>Заключение</title><p>Заключение. По данным нашего исследования, наиболее выигрышными характеристиками при выполнении поясничной лимфаденэктомии обладал лапароскопический забрюшинный доступ.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. To date, the role of lymphadenectomy in stage I endometrial cancer has been relegated to the background in favor of sentinel lymph node biopsy. Taking into account the new data on the improved survival in patients at high risk of lymph node metastasis after pelvic and para-aortic lymphadenectomy and the tendency to upstaging in accordance with the new FIGO 2023 classification, the problem of performing para-aortic lymphadenectomy becomes relevant again.</p></sec><sec><title>The study objective</title><p>The study objective: a comparative analysis of surgical accesses used in performing lumbar lymphadenectomy in endometrial cancer patients with an emphasis on the disadvantages and advantages of each surgical approach.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. Medical records of 122 endometrial cancer patients treated at the S. P. Botkin Moscow Medical Scientific Center were retrospectively analyzed. The study included patients undergoing pelvic and para-aortic lymphadenectomy, and hysterectomy through four surgical access methods: laparotomy (n=28), laparoscopic transabdominal (n=30), laparoscopic retroperitoneal (n=41) and robot-assisted retroperitoneal (n=23). The following parameters were compared between the subgroups: body mass index of patients, duration of surgery, number of removed pelvic and para-aortic lymph nodes, frequency of achieving III and IV levels of lymphadenectomy, frequency of intraand postoperative complications, length of hospital stay in the postoperative period, and frequency of transfers to intensive care unit.</p></sec><sec><title>Results</title><p>Results. Compared with other subgroups, surgery performed via laparoscopic retroperitoneal access was characterized by the shortest duration of surgery, high frequency of achieving level IV lymphadenectomy and acceptable level of intraand postoperative complications.</p></sec><sec><title>Conclusion</title><p>Conclusion. Laparoscopic retroperitoneal access was found to have greatest advantageous in performing lumbar lymphadenectomy.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>парааортальная лимфаденэктомия</kwd><kwd>робот-ассистированная лимфаденэктомия</kwd><kwd>ретроперитонеальная лимфаденэктомия</kwd><kwd>забрюшинная лимфаденэктомия</kwd><kwd>рак эндометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>para-aortic lymphadenectomy</kwd><kwd>robot-assisted lymphadenectomy</kwd><kwd>retroperitoneal lymphadenectomy</kwd><kwd>endometrial cancer</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2023 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, А.О. Шахзадовой. М., 2024. 276 с. 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