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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2016-15-4-62-69</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-388</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОПЫТ РАБОТЫ ОНКОЛОГИЧЕСКИХ УЧРЕЖДЕНИЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ONCOLOGY PRACTICE</subject></subj-group></article-categories><title-group><article-title>УСТРАНЕНИЕ ДЕФЕКТОВ ОСНОВАНИЯ ЧЕРЕПА И СРЕДНЕЙ ЗОНЫ ЛИЦА ПОСЛЕ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ РАСПРОСТРАНЕННЫХ КРАНИОМАКСИЛЛЯРНЫХ ОПУХОЛЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>CORRECTION THE SKULL BASE AND MIDFACE DEFECTS AFTER SURGICAL TREATMENT OF THE WIDESPREAD CRANIO-MAXILLARY TUMORS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чеботарев</surname><given-names>С. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Chebotarev</surname><given-names>S. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">bonya2007@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирзаян</surname><given-names>Г. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Mirzayan</surname><given-names>G. R.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">mirzayan2012@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белов</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Belov</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">belov_igor@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Примак</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Primak</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">primak_nikita@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуляев</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gulyaev</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гуляев Дмитрий Александрович, доктор медицинских наук, руководитель нейрохирургического отделения № 1, ЛРК – 2</p><p>SPIN-код: 1612-8261</p></bio><bio xml:lang="en"><p>Gulyaev Dmitry A., MD, DSc, Head of Neurosurgery Department </p><p>SPIN-code: 1612-8261</p></bio><email xlink:type="simple">gulyaevd@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. И.П. Павлова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg Pavlov State Medical University, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Северо-Западный федеральный медицинский исследовательский центр им. В.А. Алмазова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Northwest Medical Research Center named after professor V.A. Almazov, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>29</day><month>10</month><year>2016</year></pub-date><volume>15</volume><issue>4</issue><fpage>62</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чеботарев С.Я., Мирзаян Г.Р., Белов И.Ю., Примак Н.А., Гуляев Д.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Чеботарев С.Я., Мирзаян Г.Р., Белов И.Ю., Примак Н.А., Гуляев Д.А.</copyright-holder><copyright-holder xml:lang="en">Chebotarev S.Y., Mirzayan G.R., Belov I.Y., Primak N.A., Gulyaev D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/388">https://www.siboncoj.ru/jour/article/view/388</self-uri><abstract><sec><title></title><p>.Введение. Выполнение радикального оперативного пособия у пациентов с распространенными краниомаксиллярными опухолями сопровождается возникновением обширных дефектов.</p><p>Цель исследования – изучить возможности применения основных методик устранения дефектов краниомаксиллярной локализации после хирургического лечения опухолей, их влияние на качество жизни и выживаемость.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проанализированы результаты хирургического лечения 94 больных с распространенными краниомаксиллярными опухолями в зависимости от характера выполненного оперативного вмешательства, применяемой методики устранения послеоперационных дефектов.</p></sec><sec><title>Результаты</title><p>Результаты. Выполнена оценка эффективности использования различных методов в реконструкции дефектов средней зоны лица и основания черепа после хирургического лечения, их влияния на качество жизни и выживаемость. Применение онкологических методик в сочетании с первичным устранением образовавшихся дефектов позволяет добиться более высоких результатов лечения краниомаксиллярных опухолей.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Performance the radical surgical treatment in patients with widespread cranio-maxillary tumors is followed by appearance of extensive defects.</p></sec><sec><title>Objective</title><p>Objective. To explore the possibility of the applying the basic methods of eliminating defects cranio-maxillary localization after surgical treatment of tumors and their impact on quality of life and survival.</p></sec><sec><title>Material and methods</title><p>Material and methods. The results of surgical treatment of 94 patients with the widespread cranio-maxillary tumors, depending on the performed type of the surgery and method of eliminating postoperative defects were analyzed.</p></sec><sec><title>Results</title><p>Results. Efficiency of different methods of reconstruction of defects of the midface and anterior skull base and their impact on quality of life and survival after the surgery were estimated. The use of general oncological methods in combination with the methods of the primary effectively correction of formed defects allows to achieve better results in the treatment of patients with widespread cranio-maxillary tumors. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>основание черепа</kwd><kwd>опухоль</kwd><kwd>дефект</kwd><kwd>пластика</kwd><kwd>качество жизни</kwd><kwd>выживаемость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>skull base</kwd><kwd>tumor</kwd><kwd>defect</kwd><kwd>plastic</kwd><kwd>quality of life</kwd><kwd>survival</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Коновалов А.Н., Черекаев В.А., Белов А.И., Шишкина Л.В., Винокуров А.Г. 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