oncotomskСибирский онкологический журналSiberian journal of oncology1814-48612312-3168Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences10.21294/1814-4861-2016-15-5-82-88oncotomsk-410Research ArticleОБЗОРЫREVIEWSОФЭКТ/КТ В ДИАГНОСТИКЕ ВТОРИЧНОГО ОПУХОЛЕВОГО ПОРАЖЕНИЯ КОСТЕЙSPECT/CT IN DETECTION OF BONE METASTASES IN BREAST AND PROSTATE CANCERSГлушковЕ. А.GlushkovE. A.

врач-онколог; аспирант кафедры онкологии, Кировская государственная медицинская академия Минздрава России (г. Киров, Российская Федерация)

postgraduate, Oncology Department, Kirov State Medical Academy (Kirov, Russian Federation)

ujinvork@mail.ruКисличкоА. Г.KislichkoA. G.

доктор медицинских наук, профессор, заведующий кафедрой онкологии, Кировская государственная медицинская академия Минздрава России (г. Киров, Российская Федерация)

MD, Professor, Head of Oncology Department, Kirov State Medical Academy (Kirov, Russian Federation)

ФГБОУ ВО «Кировская государственная медицинская академия» Минздрава России, г. Киров 610998, г. Киров, ул. К. Маркса, 112 «Кировский областной клинический онкологический диспансер», г. КировРоссияKirov State Medical Academy, Kirov, Russia 112, K. Marx str., 610998-Kirov, Russia Kirov Regional Oncological Hospital, Kirov, RussiaRussian FederationФГБОУ ВО «Кировская государственная медицинская академия» Минздрава России, г. Киров 610998, г. Киров, ул. К. Маркса, 112РоссияKirov State Medical Academy, Kirov, Russia 112, K. Marx str., 610998-Kirov, RussiaRussian Federation2016181120161558288Copyright © Глушков Е.А., Кисличко А.Г., 20162016Глушков Е.А., Кисличко А.Г.Glushkov E.A., Kislichko A.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.siboncoj.ru/jour/article/view/410

Способностью к метастазированию в кости обладает множество злокачественных опухолей. Безусловными лидерами среди них являются злокачественные новообразования молочной железы и простаты. Прогрессирующий рост костных метастазов приводит к серьезным метаболическим нарушениям в организме и потере целостности скелета. Указанные обстоятельства влекут за собой развитие тяжелых осложнений, которые могут послужить причиной гибели пациента. Необходимость раннего выявления вторичного опухолевого поражения костей, неудовлетворительные результаты сканирования имеющимися в арсенале лучевыми методами способствовали созданию мультимодальных диагностических систем, таких как ОФЭКТ/КТ. В статье рассматривается использование ОФЭКТ/КТ в диагностике метастатического поражения скелета. Описываются основные принципы работы ОФЭКТ/КТ, их клиническое применение. Кроме того, указываются как преимущества гибридной технологии, так и ее недостатки. Приводится сравнение результатов исследований разных авторов с указанием диагностической эффективности ОФЭКТ/КТ в обнаружении вторичного опухолевого поражения костей наряду с другими методами лучевой диагностики.

Most cancers have the ability to metastasize to the bones. Absolute leaders among them are breast and prostate cancers. Progressive growth of bone metastases causes serious metabolic disturbances in the body and loss of skeletal integrity thus resulting in the development of serious complications leading to death. The need for early detection of secondary bone cancer as well as poor images obtained by using available imaging methods contributed to the creation of multimodality SPECT/CT systems. The article discusses the use of SPECT/CT in detection of metastatic involvement of the skeleton. It describes the basic principles of SPECT/CT clinical applications. In addition, both the advantages and disadvantages of the hybrid technology are shown. The results of different studies assessing the diagnostic efficacy of SPECT/CT in the detection of secondary bone tumors are compared.

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The authors declare that there are no conflicts of interest present.