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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2016-15-6-79-88</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-451</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>СЛУЧАЙ ПЕРВИЧНО-МНОЖЕСТВЕННОЙ ПЛОСКОКЛЕТОЧНОЙ КАРЦИНОМЫ ЯИЧНИКОВ И СИГМОВИДНОЙ КИШКИ</article-title><trans-title-group xml:lang="en"><trans-title>A CASE REPORT OF MULTIPLE PRIMARY SQUAMOUS CELL CARCINOMAS OF THE OVARY AND SIGMOID COLON</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Виллерт</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Villert</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виллерт Алиса Борисовна - кандидат медицинских наук, старший научный сотрудник отделения гинекологии с группой профилактики.</p><p>634009, г. Томск, пер. Кооперативный, 5. E-mail: avillert@yandex.ru. SPIN-код: 1975-0042</p></bio><bio xml:lang="en"><p>Villert Alisa B. - MD, PhD, Senior Researcher, Department of Gynecology with the Group of Cancer Prevention.</p><p>5, Kooperativny Street, 634009-Tomsk, Russia. E-mail: avillert@ yandex.ru. SPIN-code: 1975-0042</p></bio><email xlink:type="simple">avillert@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Завьялов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zavyalov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Завьялов Александр Александрович - доктор медицинских наук, ведущий научный сотрудник торако-абдоминального отделения.</p><p>634009, г. Томск, пер. Кооперативный, 5. E-mail: ZavyalovAA@oncology.tomsk.ru. SPIN-код: 5510-4043</p></bio><bio xml:lang="en"><p>Zavyalov Aleksandr A. - MD, DSc, Senior Researcher, Thoracic and Abdominal Department.</p><p>5, Kooperativny Street, 634009-Tomsk, Russia. E-mail: ZavyalovAA@oncology.tomsk.ru. SPIN-code: 5087-2394</p></bio><email xlink:type="simple">ZavyalovAA@oncology.tomsk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коломиец</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolomiets</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коломиец Лариса Александровна - доктор медицинских наук, профессор, заслуженный деятель науки РФ, заведующая отделением гинекологии с группой профилактики.</p><p>634009, г. Томск, пер. Кооперативный, 5. E-mail: kolomietsla@oncology.tomsk.ru. SPIN-код: 6316-1146</p></bio><bio xml:lang="en"><p>Kolomiets Larisa A. - MD, DSc, Professor, Head of Department of Gynecology with the Group of Cancer Prevention.</p><p>5, Kooperativny Street, 634009-Tomsk, Russia. E-mail: kolomietsla@ oncology.tomsk.ru. SPIN-code: 6316-1146</p></bio><email xlink:type="simple">kolomietsla@oncology.tomsk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фесик</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Fesik</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фесик Евгения Анатольевна - кандидат медицинских наук, врач-патологоанатом отделения патологической анатомии и цитологии.</p></bio><bio xml:lang="en"><p>Fesik Evgenia A. - MD, PhD, Pathologist, Department of Pathological Anatomy and Cytology.</p><p>5, Kooperativny Street, 634009-Tomsk, Russia. E-mail: fesik-evgenija@rambler.ru. SPIN-code: 6622-7291. </p></bio><email xlink:type="simple">fesik-evgenija@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перельмутер</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Perelmuter</surname><given-names>V. М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Перельмутер Владимир Михайлович - доктор медицинских наук, профессор, заведующий отделением патологической анатомии и цитологии.</p><p>634009, г. Томск, пер. Кооперативный, 5. E-mail: pvm@ngs.ru. SPIN-код: 6252-5391</p></bio><bio xml:lang="en"><p>Perelmuter Vladimir M. - MD, DSc, Professor, Head of Department of Pathological Anatomy and Cytology.</p><p>5, Kooperativny Street, 634009-Tomsk, Russia. E-mail: pvm@ngs.ru. SPINcode: 6252-5391</p></bio><email xlink:type="simple">pvm@ngs.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каракешишева</surname><given-names>М. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Karaleshishiva</surname><given-names>М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каракешишева Маргарита Борисовна - кандидат медицинских наук, врач эндоскопического отделения.</p><p>634009, г. Томск, пер. Кооперативный, 5. SPIN-код: 3247-8685</p></bio><bio xml:lang="en"><p>Karakeshisheva Margarita B. - MD, PhD, Physician, Endoscopic Department, Cancer Research Institute, TNMC, RAS.</p><p>5, Kooperativny Street, 634009-Tomsk, Russia. E-mail: adresprostoy@gmail.com. SPIN-code: 3247-8685</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьев</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoryev</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорьев Евгений Геннадьевич - кандидат медицинских наук, старший научный сотрудник отделения лучевой диагностики.</p><p>634009, г. Томск, пер. Кооперативный, 5. E-mail: adresprostoy@gmail.com. SPIN-код: 2079-2370</p></bio><bio xml:lang="en"><p>Grigorjev Evgeny G. - MD, PhD, Senior Researcher, Diagnostic Imaging Department.</p></bio><email xlink:type="simple">adresprostoy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Литвяков</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Litvyakov</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Литвяков Николай Васильевич - доктор биологических наук, заведующий лабораторией онковирусологии, НИИО, ТНИМЦ РАН; старший научный сотрудник, НИТГУ.</p><p>634009, г. Томск, пер. Кооперативный, 5. E-mail: nvlitv72@yandex.ru. SPIN-код: 2546-0181</p></bio><bio xml:lang="en"><p>Litviakov Nikolay V. - DSc, Head of Laboratory of Viral Oncology.</p><p>5, KooperativnyStreet, 634009-Tomsk, Russia. E-mail: nvlitv72@yandex.ru. SPIN-code: 2546-0181</p></bio><email xlink:type="simple">nvlitv72@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт онкологии, Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Medical</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт онкологии, Томский национальный исследовательский медицинский центр Российской академии наук; Сибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Medical Sciences; Siberian State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>15</volume><issue>6</issue><fpage>79</fpage><lpage>88</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Виллерт А.Б., Завьялов А.А., Коломиец Л.А., Фесик Е.А., Перельмутер В.М., Каракешишева М.Б., Григорьев Е.Г., Литвяков Н.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Виллерт А.Б., Завьялов А.А., Коломиец Л.А., Фесик Е.А., Перельмутер В.М., Каракешишева М.Б., Григорьев Е.Г., Литвяков Н.В.</copyright-holder><copyright-holder xml:lang="en">Villert A.B., Zavyalov A.A., Kolomiets L.A., Fesik E.A., Perelmuter V.М., Karaleshishiva М., Grigoryev E.G., Litvyakov N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/451">https://www.siboncoj.ru/jour/article/view/451</self-uri><abstract><p>Плоскоклеточная карцинома яичника является редкой патологией, как и плоскоклеточная карцинома сигмовидной кишки, что обусловливает отсутствие статистических данных, а также дефицит представлений об их этиологии и патогенезе. Первично-множественная плоскоклеточная карцинома яичников и сигмовидной кишки составляет предмет дифференциальной диагностики рака сигмовидной кишки с метастатическим поражением яичников. Дана патологоанатомическая и клиническая характеристика опухолей, показаны основные факты, свидетельствующие в пользу первично-множественного характера процесса. Показана ассоциация плоскоклеточных карцином яичника и толстой кишки с вирусом папилломы человека 16-го типа.</p></abstract><trans-abstract xml:lang="en"><p>Squamous cell ovarian and sigmoid colon carcinomas are extremely rare malignancies. Because of their rarity, it is difficult to investigate the clinical characteristics and prognosis of patients with theses malignancies, and therefore, the increased interest in each clinical case report is highly relevant. Multiple primary squamous cell ovarian and sigmoid colon carcinomas are the subject of discussion and differential diagnosis of sigmoid colon cancer with secondary ovarian cancer. Histopathological and clinical characteristics of the tumors were present and evidences in favor of the multiple primary malignancies were given. The association of squamous cell ovarian and sigmoid colon carcinomas with human papilloma virus type 16 was shown.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>плоскоклеточная карцинома яичников</kwd><kwd>плоскоклеточная карцинома толстой кишки</kwd><kwd>первично-множественные опухоли</kwd><kwd>вирус папилломы человека</kwd></kwd-group><kwd-group xml:lang="en"><kwd>squamous cell ovarian carcinoma</kwd><kwd>squamous cell sigmoid colon carcinoma</kwd><kwd>multiple primary tumors</kwd><kwd>human papillomavirus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ayhan A., Bukulmez O., Genc C., Karamursel B.S., Ayhan A. Mature cystic teratomas of the ovary: case series from one institution over 34 years. 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