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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21294/1814-4861-2017-16-1-104-108</article-id><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-499</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>ПЭТ-КТ КАРТИНА ДИССЕМИНАЦИИ ДОБРОКАЧЕСТВЕННОЙ ЛЕЙОМИОМЫ</article-title><trans-title-group xml:lang="en"><trans-title>PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Субботин</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Subbotin</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог отделения радионуклидной диагностики, Челябинский окружной клинический онкологический диспансер; ассистент кафедры онкологии, лучевой диагностики и терапии, Южно-Уральский медицинский университет (г. Челябинск, Россия)</p></bio><bio xml:lang="en"><p>MD, Radiologist, Department of Nuclear Medicine, Chelyabinsk Regional Cancer Hospital, lecturer, Department of Oncology, Diagnostic Imaging and Radiation Therapy, South-Ural State Medical University (Chelyabinsk, Russia)</p></bio><email xlink:type="simple">acsubbotin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Важенин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vazhenin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, член-корреспондент РАН, заслуженный врач РФ, главный врач Челябинского окружного клинического онкологического диспансера; заведующий кафедрой онкологии, лучевой диагностики и терапии, Южно-Уральский медицинский университет (г. Челябинск, Россия)</p><p>SPIN-код: 1350-9411.</p></bio><bio xml:lang="en"><p>MD, Professor, Associate Member of Russian Academy of Sciences, Head of Chelyabinsk Regional Cancer Hospital; Head of Department of Oncology, Diagnostic Imaging and Radiation Therapy, South-Ural State Medical University (Chelyabinsk, Russia)</p><p>SPIN-code: 1350-9411</p></bio><email xlink:type="simple">rochel@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афанасьева</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Afanasyeva</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, заведующая отделением радионуклидной диагностики, Челябинский окружной клинический онкологический диспансер; ассистент кафедры онкологии, лучевой диагностики и терапии, Южно-Уральский медицинский университет (г. Челябинск)</p></bio><bio xml:lang="en"><p>MD, PhD, Head of Department of Nuclear Medicine, Chelyabinsk Regional Cancer Hospital; Lecturer, Department of Oncology, Diagnostic Imaging and Radiation Therapy, South-Ural State Medical University (Chelyabinsk, Russia)</p></bio><email xlink:type="simple">afanas_ng@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Челябинский окружной клинический онкологический диспансер», г. Челябинск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chelyabinsk State Regional Oncological Hospital, Chelyabinsk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>22</day><month>03</month><year>2017</year></pub-date><volume>16</volume><issue>1</issue><fpage>104</fpage><lpage>108</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Субботин А.С., Важенин А.В., Афанасьева Н.Г., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Субботин А.С., Важенин А.В., Афанасьева Н.Г.</copyright-holder><copyright-holder xml:lang="en">Subbotin A.S., Vazhenin A.V., Afanasyeva N.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/499">https://www.siboncoj.ru/jour/article/view/499</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Способность к метастазированию считается одним из ключевых признаков злокачественных опухолей. Однако в литературе описана возможность диссеминации гистологически верифицированных доброкачественных опухолей – лейомиом матки. Диагностика метастазирующей лейомиомы является сложной задачей из-за исключительной редкости данной патологии, в то же время выявление доброкачественности процесса определяет тактику лечения, которая существенно отличается от подходов к терапии злокачественных новообразований. Описание клинического случая. Приводим наблюдение редкого случая диссеминации лейомиомы. У пациентки 72 лет имелись признаки, типичные для злокачественного образования яичников: узловые образования брюшной полости, асцит, метастаз в тело поясничного позвонка, высокий уровень СА-125. По данным ПЭТ-КТ в мягкотканном образовании, разрушающем тело поясничного позвонка, и крупнейшем образовании брюшной полости имелось повышение метаболической активности, типичное для злокачественных опухолей. Однако гистологическое и иммуногистохимическое исследования подтвердили диссеминацию доброкачественной опухоли. Заключение. Наличие признаков, свидетельствующих о наличии злокачественного новообразования, таких как отдаленные метастазы и высокий уровень онкомаркера СА-125, повышенная метаболическая активность по данным ПЭТ в редких случаях может наблюдаться при доброкачественных опухолях.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>The ability to metastasize is considered to be one of the key features of malignant tumors. However, the literature describes the possibility of dissemination of histologically verified benign tumors – uterine leiomyoma. Diagnosis of metastatic leiomyoma is a challenging task for the doctor, due to the extreme rarity of this disease, at the same time revealing the purity of the process is determining the further tactics of treatment, significantly different from the treatment of malignancies. Case report. We presented a rare case of dissemination of benign tumors – leiomyomas. The female patient of 72 years old had signs of typical malignant tumors of the ovaries, such as nodules of the abdominal cavity, ascites and metastases in the body of the lumbar vertebra, increased level of CA-125. PET-CT revealed increased FDG uptake in soft-tissue neoplasm that destruct the body of the lumbar vertebrae and the nodules in the abdominal cavity with increased metabolic activity, typical for malignant tumors. However, histological examination with immunohistochemical verification confirmed the presence of dissemination of benign tumors. Conclusion. The presence of signs, typical for the malignant tumor, such as the presence of distant metastases of various localizations, a high level of CA-125 tumor marker, increased metabolic activity on PET scan in rare cases, may occur with benign tumors. Therefore, diagnosis of tumors should always be integrated, with the obligatory account all available clinical, laboratory and instrumental data.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лейомиома</kwd><kwd>диссеминированный перитонеальный лейомиоматоз</kwd><kwd>ПЭт-Кт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>leiomyoma</kwd><kwd>leiomyomatosis peritonealis disseminate</kwd><kwd>PET-CT</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rakhshani N., Hormazdi M., Abolhasani M., Shahzadi M. Benign Metastasizing Leiomyoma of the Uterus. Arch Iran Med. 2007 Jan; 10 (1): 97–9. doi: 07101/AIM.0021.</mixed-citation><mixed-citation xml:lang="en">Rakhshani N., Hormazdi M., Abolhasani M., Shahzadi M. Benign Metastasizing Leiomyoma of the Uterus. 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