oncotomskСибирский онкологический журналSiberian journal of oncology1814-48612312-3168Tomsk National Research Medical Сепtеr of the Russian Academy of Sciencesoncotomsk-5Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯCLINICAL STUDIESВСПЫШКА ВНУТРИБОЛЬНИЧНОЙ ИНФЕКЦИИ, ВЫЗВАННОЙ МУЛЬТИРЕЗИСТЕНТНЫМИ (MDR) ШТАММАМИ K. PNEUMONIAEOUTBREAK OF HOSPITAL-AQUIRED INFECTION CAUSED BY MULTIDRUG RESISTANT STRAINS OF K. PNEUMONIAEГригорьевскаяЗ. В.GrigoryevskayaZ. V.zlatadoc@list.ruПетуховаИ. Н.PetukhovaI. N.

115448, г. Москва, Каширское шоссе

zlatadoc@list.ruдмитриеваН. В.DmitrievaN. V.

115448, г. Москва, Каширское шоссе

zlatadoc@list.ruЛаборатория микробиологической диагностики и лечения инфекций в онкологии ФГБУ «РОНЦ им. Н.Н. Блохина» РАМНРоссия2014050220160258Copyright © Григорьевская З.В., Петухова И.Н., дмитриева Н.В., 20162016Григорьевская З.В., Петухова И.Н., дмитриева Н.В.Grigoryevskaya Z.V., Petukhova I.N., Dmitrieva N.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.siboncoj.ru/jour/article/view/5

Серьезной клинической проблемой последних нескольких лет являются штаммы K. pneumoniaе, вырабатывающие металло-бета-лактамазы (карбапенемазы). Карбапенемаз-продуцирующие штаммы (КРС) K. pneumoniaе резистентны почти ко всем известным антибиотикам и в 40–50 % случаев приводят к смерти пациента. В большинстве клиник мира проводят эпидемиологические расследования инфекционных вспышек, инициированных проблемными микроорганизмами. Организация эпидемиологической политики стационара позволяет контролировать ситуацию. В сентябре 2013 г. в ОРИТ ФГБУ РОНЦ им. Н.Н. Блохина была зафиксирована вспышка инфекции, вызванная MDR штаммами K. Pneumoniaе, в связи с чем было проведено эпидемиологическое расследование.

The prevalence of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is increasing globally and is a major clinical concern. Carbapenemase-producing strains (K. Pneumoniaе) can develop resistance to nearly all known antibiotics and in 40-50% of cases lead to death of the patient. Epidemiological studies of outbreaks of infections caused by pathogenic microorganisms are carried out in most clinics of the world. Creation of hospital epidemiology program allows the control of hospital’s infection. In September, 2013, the outbreak of infection caused by MDR strains of K. Pneumoniaе was registered at the N.N. Blokhin Russian Cancer Research Center, and the epidemiologic study was conducted.

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The authors declare that there are no conflicts of interest present.