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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">oncotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский онкологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian journal of oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-4861</issn><issn pub-type="epub">2312-3168</issn><publisher><publisher-name>Tomsk National Research Medical Сепtеr of the Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">oncotomsk-64</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛАБОРАТОРНЫЕ И ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LABORATORY AND EXPERIMENTAL STUDIES</subject></subj-group></article-categories><title-group><article-title>ОПЫТ ДИАГНОСТИКИ РЕДКИХ ОПУХОЛЕЙ ПИЩЕВАРИТЕЛЬНОЙ СИСТЕМЫ У ЛАБОРАТОРНЫХ МЫШЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>EXPERIENCE IN DIAGNOSING RARE DIGESTIVE SYSTEM NEOPLASMS IN LABORATORY MICE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Манских</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Manskikh</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119992, г. Москва, Ленинские горы, стр. 73</p></bio><email xlink:type="simple">manskikh@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ганчарова</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Gancharova</surname><given-names>О. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119992, г. Москва, Ленинские горы, стр. 73</p></bio><bio xml:lang="en"><p>73, Leninskie Gory, 119992- Moscow</p></bio><email xlink:type="simple">manskikh@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ ВПО «Московский государственный университет им. М.В. Ломоносова», г. Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.V. Lomonosov Moscow State University, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>12</day><month>02</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>39</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Манских В.Н., Ганчарова О.С., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Манских В.Н., Ганчарова О.С.</copyright-holder><copyright-holder xml:lang="en">Manskikh V.N., Gancharova О.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.siboncoj.ru/jour/article/view/64">https://www.siboncoj.ru/jour/article/view/64</self-uri><abstract><p>Описаны три случая редко встречающихся опухолей у лабораторных мышей – миоэпителиальная карцинома слюнной железы, злокачественная нейроэндокринная опухоль (карциноид) слепой кишки, инсулярная карцинома поджелудочной железы. Карциноид слепой кишки впервые диагностирован как спонтанное новообразование у мышей без генетических модификаций. Представлен анализ диагностических признаков этих неоплазм и их особенностей в сравнении со случаями, описанными в литературе.</p></abstract><trans-abstract xml:lang="en"><p>Three rare tumors occurring in laboratory mice, namely: myoepithelial carcinoma of the salivary gland, malignant neuroendocrine tumors (carcinoid) of the cecum and insular carcinoma of the pancreas have been described. Carcinoid tumor of the cecum was first diagnosed as a spontaneous neoplasm in mice without genetic modification. Analysis of diagnostic features of these neoplasms and their characteristics in comparison with the published cases has been presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>опухоли у лабораторных мышей</kwd><kwd>миоэпителиальная карцинома</kwd><kwd>злокачественная нейроэндокринная опухоль</kwd><kwd>инсулярная карцинома</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tumors in laboratory mice</kwd><kwd>myoepithelial carcinoma</kwd><kwd>malignant neuroendocrine tumor</kwd><kwd>insular carcinoma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Frith C.H., Sheldon W.D. Hyperplasia, Adenoma, and Carcinoma of Pancreatic Islets, Mouse // Monographs on Pathology of Laboratory Animals. Endocrine System. Springer-Verlag. Berlin-Heidelberg, 1996. P. 361–367.</mixed-citation><mixed-citation xml:lang="en">Frith C.H., Sheldon W.D. 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