CRYOSURGERY IN THE TREATMENT OF LIVER CANCER: A CASE REPORT
https://doi.org/10.21294/1814-4861-2019-18-4-112-115
Abstract
Background. Hepatocellular carcinoma is the most common liver cancer and is a leading cause of cancerrelated death worldwide. Its aggressiveness and extensive dissemination lead to a poor patient prognosis. The 5-year survival rate does not exceed 15 %. Despite advances in imaging techniques, its curable rate remains low, because signs and symptoms of liver cancer do not usually appear until the late stages. There is no standard curative treatment for advanced liver cancer.
Description. We present the case of a 56- year-old female patient with stage T3N0M0 hepatocellular carcinoma. The patient had a tumor of 20 cm in diameter and 2400 g in weight. The patient underwent right hemihepatectomy and cryodestruction of the liver stump along the resection margin. No evidence of tumor recurrence was found with a follow-up of 12 years.
Conclusion. Cryodestruction of the liver stump along the resection margin increases the potential for a higher cure rate in patients with hepatocellular carcinoma, even in cases of extensive organ damage in the absence of metastasis and tumor ingrowth into surrounding organs.
About the Authors
N. V. Merzlikin
Siberian State Medical Universty
Russian Federation
Russian Federation
MD, Professor, Head of the Department of Surgery with the Course of Traumatology and Orthopedics,
2, Moscovsky Trakt, 634050-Tomsk
L. U. Petrov
Siberian State Medical Universty
Russian Federation
Russian Federation
MD, PhD, Assistant Professor of the Department of Surgery with the Course of Traumatology and Orthopedics,
2, Moscovsky Trakt, 634050-Tomsk
V. F. Tskhai
Siberian State Medical Universty
Russian Federation
Russian Federation
MD, Professor, Department of Surgery with the Course of Traumatology and Orthopedics,
2, Moscovsky Trakt, 634050-Tomsk
E. A. Pshenichnikova
Pathology Department, City Hospital № 3
Russian Federation
Russian Federation
MD, Pathology Department,
3, Nakhimova Street, 634045-Tomsk
A. P. Sarueva
Siberian State Medical Universty
Russian Federation
Russian Federation
MD, Department of Surgery with the Course of Traumatology and Orthopedics,
2, Moscovsky Trakt, 634050-Tomsk
References
1. Afanasyev S.G., Tuzikov S.A. Inoperable liver tumors (literature review). Siberian Journal of Oncology. 2006; 1: 49–54. (in Russian).
2. Dolgushin B.I., Kosyrev V.Yu., Ramprabanant S. Radiofrequency ablation in oncology. Practical Oncology. 2007; 8(4): 219–226. (in Russian).
3. Alperovich B.I., Paramonova L.M., Merzlikin N.V. Modern possibilities of cryosurgery of the liver and pancreas. Pirogov Russian Journal of Surgery. 1992; 68(1): 104–107. (in Russian).
4. Merzlikin N.V., Tskhai V.F., Brazhnikova N.A., Komkova T.B., Salo V.N., Maximov M.A., Navasardan V.G., Noroeva T.A. Cryosurgery of liver tumors. Siberian Journal of Oncology. 2018; 17(2): 41–48. (in Russian). doi: 10.21294/1814-4861-2018-17-2-41-48.
5. Datsenko B.M., Sandomirsky B.P., Tamm T.I., Datsenko A.B., Muradov T.R. Local cryodestruction of the liver. Annals of surgical hepatology. 1998; 3(3): 269. (in Russian).
6. Egorenkov V.V. Treatment of malignant tumors of the liver using local cryodestruction methods. Practical Oncology. 2008; 9(4): 202–208. (in Russian).
7. Alperovich B.I., Merzlikin N.V., Komkovа T.B. Cryosurgical operations for diseases of the liver and pancreas: a guidelines for doctors. Moscow, 2015. 240. (in Russian).
Review
For citations:
Merzlikin N.V., Petrov L.U., Tskhai V.F., Pshenichnikova E.A., Sarueva A.P. CRYOSURGERY IN THE TREATMENT OF LIVER CANCER: A CASE REPORT. Siberian journal of oncology. 2019;18(4):112-115. (In Russ.) https://doi.org/10.21294/1814-4861-2019-18-4-112-115
Views:
969
Email this article 
