MORPHOFUNCTIONAL STATE OF BUCCAL EPITHELIOCYTES IN LUNG CANCER PATIENTS
Abstract
Parameters of epitheliocytes in buccal mucosal smears of lung cancer patients were analyzed. The study results showed disturbances in the process of maturation and differentiation of the oral mucosal epithelium, significant structural and functional changes in buccal epitheliocytes, which were more pronounced after chemotherapy
About the Authors
O. P. Bochkareva
Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
E. P. Krasnozhenov
Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
V. E. Goldberg
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
N. O. Popova
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
L. R. Mustafina
Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
References
1. Иванова О.В. Прогнозирование, профилактика и лечение осложнений в полости рта у больных, получающих цитостатики и лучевую терапию: Автореф. дис. ... канд. мед. наук. Астрахань, 2001. 22 с.
2. Кузьмина Е.Г., Неприна Г.С., Ватин О.Е. и др. Коррекция вторичных иммунодефицитных состояний индуцированных химиолучевой терапией у онкологических больных // Российский онкологический журнал. 2003. №2. С. 32 – 36.
3. Токмакова С.И., Луницына Ю.В. Клинико-морфологическая характеристика язвенно-некротического стоматита на фоне цитостатической терапии острого лейкоза // Сибирский онкологический журнал. 2012. № 4 (52). С. 30–34.
4. Brown C.G., Wingard J. Clinical consequences of oral mucositis // Semin. Oncol. Nurs. 2004. Vol. 20 (1). P. 16–21.
5. Epstein J.B., Schubert M.M. Oropharyngeal mucositis in cancer therapy. Review of pathogenesis, diagnosis, and management // Oncology (Huntingt). 2003. Vol. 17 (12). P. 1767–1779.
6. Sonis S.T. Mucositis: The impact, biology and therapeutic opportunities of oral mucositis // Oral Oncol. 2009. Vol. 45(12). P. 1015–1020.
Review
For citations:
Bochkareva O.P., Krasnozhenov E.P., Goldberg V.E., Popova N.O., Mustafina L.R. MORPHOFUNCTIONAL STATE OF BUCCAL EPITHELIOCYTES IN LUNG CANCER PATIENTS. Siberian journal of oncology. 2013;(3):57-60. (In Russ.)
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