TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES
https://doi.org/10.21294/1814-4861-2021-20-2-5-12
Abstract
Regenerative medicine represents the field of medicine that aims to grow lost or damaged human organs and tissues. The promise of regenerative medicine focuses on the development of therapy that can regenerate and restore tissues and organs in the human body. The regenerative medicine has the potential of cell renewal in our body, reaching about a kilogram per day, tens of tons in our life. Recent data indicate that a tumor is a tissue that largely repeats the pattern of growth and regeneration of normal tissue. Similar to normal stem cells, tumor stem cells are capable of initiating tumor and its growth. Scientists consider that cancer is a payment for multicellularity [1]. Undoubtedly, this potential must be learned to manage. This is a very difficult problem, since many fundamental mechanisms of cell formation and death have not been fully understood. The development of regenerative medicine as a fundamentally new type of medicine will make it possible not only to control stem cell renewal, but also to prevent malignant transformation. The identification of proteins, micro-RNAs and other factors that regulate the formation and death of cells will identify potential targets for both stimulating endogenous regeneration and controlling cancer.
Keywords
Supporting agencies: This research was supported by the Russian Science Foundation (Project No. 19-75-30007).
About the Author
V. A. Tkachuk
Medical Research and Education Center, Institute for Regenerative Medicine,
Lomonosov Moscow State University
Russian Federation
Russian Federation
DSc, Member of the Russian Academy of Sciences, Director of Medical Research and Education Center; Head of Biochemistry and Molecular Medicine
Researcher ID (WOS): J-9357-2012. Author ID (Scopus): 24455385800
27/10, Lomonosovsky prospect, 119192, Moscow, Russia
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Review
For citations:
Tkachuk V.A. TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES. Siberian journal of oncology. 2021;20(2):5-12. (In Russ.) https://doi.org/10.21294/1814-4861-2021-20-2-5-12
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