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LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA

https://doi.org/10.21294/1814-4861-2021-20-4-30-38

Abstract

The aim of the study was to assess the lung cancer incidence and mortality in the Khanty-mansi autonomous okrug – Yugra during the period 1999–2019.

Material and methods. We have studied the lung cancer incidence and mortality rates in Yugra over the last 21 years (1999–2019).

Results. In Yugra, the lung cancer (lc) incidence rates increased by 24.7 % from 1999 to 2019, demonstrating higher rates than those in the Russian Federation (RF), where lc incidence rates decreased by 20.3 %. In 2019, the age-standardized incidence rate was 30.5 per 100,000 (22.7 for RF); the age-standardized mortality rate was 16.4 per 100,000 (18.4 for RF). The mortality rate from lc in Yugra was 9.6 times higher in males than in females (35.5 vs. 3.7 per 100,000). The cross-correlation analysis revealed a correlation between the lc incidence/mortality and air pollution in Yugra. The main carcinogens in Yugra were formaldehyde, phenol, nitrogen dioxide, and benzapyrene. The assessment of the relationship between the age-standardized lc incidence/mortality rates and the amount of pollutants emitted into the atmosphere revealed that their synergistic effects with tobacco smoking can double the risk of lung cancer development. The increase in the number of chest computed tomography (ct) scans performed in the context of the pandemic caused by covid-19 infection led to an 18 % increase in the number of incidentally detected pulmonary nodules, of which 9 % of cases were diagnosed as lc.

Conclusion. The lc incidence rates in Yugra tended to increase. The high rate of lc incidence is caused by man-made and natural factors, which requires the implementation of a screening program with the use of low-dose computed tomography in order to improve the early detection and prevention of this disease.

About the Authors

A. A. Mordovskii
Regional Oncology Dispensary
Russian Federation

 MD, Oncologist

24/2, Energetikov Street, 628408, Surgut, Russia 



A. A. Aksarin
Regional Oncology Dispensary
Russian Federation

 MD, PhD, Head of the Clinical Diagnostic Center of Oncology

24/2, Energetikov Street, 628408, Surgut, Russia 



A. M. Parsadanyan
Oncology Medical Institute of the State Educational Institution of Higher Professional Education of Surgut State University; Regional Oncology Dispensary 
Russian Federation

 MD, DSc, Professor; Oncologist

24/2, Energetikov Street, 628408, Surgut, Russia 



M. D. Ter-Ovanesov
State Medical Institution Hospital No. 40; Researcher at the Dmitrii Rogachev, Research Institute of Oncology and Hematology; Russian Academy of Medical Sciences 
Russian Federation

 MD, DSc, Professor, Deputy Head Physician for Medical Care (Organization of Surgical and Oncological Care); Chief;  Head of the Department of Oncology and Hematology, Faculty of Advanced Medical Education

 7, Kasatkina Street, 129301, Moscow, Russia 



P. P. Troyan
Regional Oncology Dispensary
Russian Federation

 MD, Head of the Department of the Clinical Diagnostic Center of Oncology

 24/2, Energetikov Street, 628408, Surgut, Russia 



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Review

For citations:


Mordovskii A.A., Aksarin A.A., Parsadanyan A.M., Ter-Ovanesov M.D., Troyan P.P. LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA. Siberian journal of oncology. 2021;20(4):30-38. (In Russ.) https://doi.org/10.21294/1814-4861-2021-20-4-30-38

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ISSN 1814-4861 (Print)
ISSN 2312-3168 (Online)