THE DIAGNOSTIC EFFICACY OF SPECT/CT IN DETECTION OF BONE METASTASES IN PATIENTS WITH BREAST AND PROSTATE CANCER
Abstract
The present study was undertaken to evaluate the benefit of single photon emission computed tomography/ computed tomography (SPECT/CT) over SPECT alone, osteoscintigraphy (OSG), CT and conventional X-ray for the detection of bone metastasis in patients with breast cancer (BC) and prostate cancer (PC). 72 BC patients and 17 PC patients at high risk of developing bone metastasis were examined by (SPECT/ CT), SPECT,OSG,CTand conventional X-ray. Bone metastases were detected in 33 (37.1 %) patients. It was found that the diagnostic efficacy (sensitivity, specificity and accuracy) of SPECT/CT was significantly superior to that of the other types of imaging modalities in detection of bone metastases from BC. In addition, the combination of SPECT with CT resulted in a change in SPECT and CT findings on skeletal metastasis in 5 (6 %) and 11 (12 %) cases, respectively.
About the Authors
Е. А. Glushkov
Kirov State Medical Academy, Kirov;
Kirov Regional Clinical Oncology Center
Russian Federation
Russian Federation
Glushkov Evgeny Alexandrovich, postgraduate, Kirov State Medical Academy.
Е-mail: ujinvork@mail.ru. SPIN-code: 7561-7349.
A. G. Kislichenko
Kirov State Medical Academy, Kirov
Russian Federation
Russian Federation
Kislichko Anatoly Grigorievich, MD, DSc, Professor, Head of Oncology Department.
М. S. Ramazanova
Kirov State Medical Academy, Kirov;
Kirov Regional Clinical Oncology Center
Russian Federation
Russian Federation
Ramazanova Madina Sultanovna, MD, PhD, Associate professor, Oncology Department, Kirov State Medical Academy.
Е-mail: ramazanovam@inbox.ru. SPIN-code: 7161-5909.
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Review
For citations:
Glushkov Е.А., Kislichenko A.G., Ramazanova М.S. THE DIAGNOSTIC EFFICACY OF SPECT/CT IN DETECTION OF BONE METASTASES IN PATIENTS WITH BREAST AND PROSTATE CANCER. Siberian journal of oncology. 2015;(6):19-25. (In Russ.)
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