Preview

Siberian journal of oncology

Advanced search

Microsurgical reconstruction of the skull base and midface after orbitomaxillary resections for malignant tumors

https://doi.org/10.21294/1814-4861-2021-20-6-88-95

Abstract

Background. Orbitomaxillary resection includes exenteration of the orbital contents with resection of the inferior orbital and medial walls. The main goals are: reconstruction of soft tissue and bone structure defects, tamponade of the orbital cavity and/or its preparation for further ocular prosthetics, and reconstruction of the skull base defect. The purpose of the study to present the immediate results of orbitomaxillary resections in patients with malignant neoplasms of the skull base and midface. Material and methods. Between 2014 and 2020, 6 patients who previously underwent surgery for primary cancer (n=3) and recurrent cancer (n=3) were treated at the Head and Neck cancer department of N.N. Blokhin National medical Research center of oncology. To reconstruct defects after resection of bone structures (maxilla, frontal and nasal bones) and skin, a musculocutaneous alt-flap was used in 3 (50 %) cases and a fascial skin radial flap in 3 (50 %) cases. Results. The aesthetic result was assessed in 6 patients. In all cases, a satisfactory result was obtained. None of the patients who underwent resection of the dura mater followed by reconstruction had no symptoms of liquorrhea in the postoperative period. Conclusion. Flap selection depends on the defect size. In cases with a small defect size (up to 70 cm3), reconstruction with the radial fascial skin flap can be performed. If the defect size is more than 71 cm3, reconstruction with musculocutaneous alt flap can be the method of choice.

About the Authors

M. V. Bolotin
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation

 MD, PhD, Senior Researcher

 23, Kashirskoe shosse, 115478, Moscow, Russia 



A. M. Mudunov
Clinical Hospital «Lapino» 
Russian Federation

 MD, DSc, Head of the Department

 111, Uspenskoye Shosse, Lapino, Odintsovky District, Moscow region, Russia 



V. A. Sobolevsky
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation

 MD, DSc, Head of the Department

  23, Kashirskoe shosse, 115478, Moscow, Russia 



I. M. Gelfand
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation

 MD, PhD, Oncologist 

 23, Kashirskoe shosse, 115478, Moscow, Russia 



I. V. Orlova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation

 MD, Resident 

 23, Kashirskoe shosse, 115478, Moscow, Russia 



A. A. Akhundov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation

 MD, DSc, Senior Researcher 

 23, Kashirskoe shosse, 115478, Moscow, Russia 



References

1. Valentini V., Fabiani F., Nicolai G., Torroni A., Gennaro P., Marianetti T.M., Iannetti G. Use of Microvascular Free Flaps in the Reconstruction of the Anterior and Middle Skull Base. J Craniofac Surg. 2006; 17(4): 790–6. doi:10.1097/00001665-200607000-00035.

2. Cherekaev V.A., Kadasheva A.B., Golbin D.A., Belov A.I., Kozlov A.V., Reshetov I.V., Lasunin N.V., Spirin D.S. Surgery of tumors of the skull base spreading into the orbit, paranasal sinuses, nasal cavity, pterygopalatine and infratemporal fossa: history and current state of diagnosis and approaches to surgical treatment. Questions of Neurosurgery named by N.N. Burdenko. 2013; 77(5): 3–15. (in Russian).

3. Chebotarev S.Y., Mirzayan G.R., Belov I.Yu., Primak N.A., Gulyaev D.A. Correction the skull base and midface defects after surgical treatment of the widespread cranio-maxillary tumors. Siberian journal of oncology. 2016; 15(4): 62–9. (in Russian). doi: 10.21294/1814-4861-2016-15-4-62-69.

4. Shah J.P., Snehal G., Singh P.B., Reshetov I.V. Surgery and oncology of the head and neck. Moscow, 2017. 480 p. (in Russian).

5. Smith R.R., Klopp C.T., Williams J.M. Surgical treatment of cancer of the frontal sinus and adjacent areas. Cancer. 1954 Sep; 7(5): 991–4.

6. Ganly I., Patel S.G., Singh B., Kraus D.H., Bridger P.G., Cantu G., Cheesman A., De Sa G., Donald P., Fliss D.M., Gullane P., Janecka I., Kamata S.E., Kowalski L.P., Levine P.A., Medina Dos Santos L.R., Pradhan S., Schramm V., Snyderman C., Wei W.I., Shah J.P. Craniofacial resection for malignant paranasal sinus tumors: Report of an International Collaborative Study. Head Neck. 2005 Jul; 27(7): 575–84. doi: 10.1002/hed.20165.

7. Nicolai P., Battaglia P., Bignami M., Bolzoni Villaret A., Delù G., Khrais T., Lombardi D., Castelnuovo P. Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10-year experience. Am J Rhinol. 2008 May-Jun; 22(3): 308–16. doi: 10.2500/ajr.2008.22.3170.

8. Hanna E., DeMonte F., Ibrahim S., Roberts D., Levine N., Kupferman M. Endoscopic resection of sinonasal cancers with and without craniotomy: oncologic results. Arch Otolaryngol Head Neck Surg. 2009 Dec; 135(12): 1219–24. doi: 10.1001/archoto.2009.173.

9. Lund V.J., Wei W.I. Endoscopic surgery for malignant sinonasal tumours: an eighteen year experience. Rhinology. 2015 Sep; 53(3): 204–11.

10. Roxbury C.R., Ishii M., Richmon J.D., Blitz A.M., Reh D.D., Gallia G.L. Endonasal endoscopic surgery in the management of sinonasal and anterior skull base malignancies. Head Neck Pathol. 2016 Mar; 10(1): 13–22.

11. De Alencastro L.F., De Alencastro L.C., Martins C., Lodetti A., Cardoso A.C.C., Faria M., Inoue K., Osawa S., Rhoton A.L. Transmaxillary endscopic approach to contralateral parasellar lesions. Transnasal endoscopic skull base and brain surgery: Tips and pearls. New York: Thieme; 2011. 314 p.

12. Jones N.F., Sekhar L.N., Schramm V.L. Free rectus abdominis muscle flap reconstruction of the middle and posterior cranial base. Plast Reconstr Surg. 1986 Oct; 78(4): 471–9. doi: 10.1097/00006534-198610000-00005.

13. Westbury G., Wilson J.S., Richardson A. Combined craniofacial resection for malignant disease. Am J Surg. 1975 Oct; 130(4): 463–9. doi: 10.1016/0002-9610(75)90485-7.

14. Sartoris A., Cortesina G., Busca G.P., Pia F., Giordano C., Bussi M., Amasio E., Pisani P. La resezione cranio-facciale anteriore nel trattamento dei tumori maligni rino-sinusali ad estensione endocranica. Acta Otorhinolaryngologica Italica. 1991; 11(3): 317–327.

15. Wornom I.L., Neifeld J.P., Mehrhof A.I., Young H.F., Chinchilli V.M. Closure of craniofacial defects after cancer resection. Am J Surg. 1991; 162: 408–11.

16. Miller M.J., Schusterman M.A., Reece G.P., Kroll S.S. Microvascular Craniofacial Reconstruction in Cancer Patients. Ann Surg Oncol. 1995; 2(2): 145–50.

17. Calle A.R., Díaz R.G., Rodríguez I.Z., García A.F., Aniceto G.S. Free flaps in skull base reconstruction. Int J Oral Maxillofac Surg. 2013 Oct; 42(10). doi: 10.1016/j.ijom.2013.07.415.

18. Disa J.J., Pusic A.L., Hidalgo D.H., Cordeiro P.G. Simplifying microvascular head and neck reconstruction: a rational approach to donor site selection. Ann Plast Surg. 2001; 47(4): 385–9. doi: 10.1097/00000637-200110000-00004.

19. Jones N.F., Johnson J.T., Shestak K.C., Myers E.N., Swartz W.M. Microsurgical reconstruction of the head and neck: interdisciplinary collaboration between head and neck surgeons and plastic surgeons in 305 cases. Ann Plast Surg. 1996 Jan; 36(1): 37–43. doi: 10.1097/00000637-199601000-00008.

20. McLean D.H., Buncke H.J. Jr.Autotransplant of omentum to a large scalp defect, with microsurgical revascularization. Plast Reconstr Surg. 1972 Mar; 49(3): 268–74. doi: 10.1097/00006534-197203000-00005.

21. Sartoris A., Cortesina G., Busca G.P., Pia F., Giordano C., Bussi M., Amasio E., Pisani P. (1991). La resezione cranio-facciale anteriore nel trattamento dei tumori maligni rino-sinusali ad estensione endocranica. Acta Otorhinolaryngologica Italica. 1991; 11(3): 317–327.

22. Cantu` G., Solero C.L., Pizzi N., Salvatory P., Mattavelli F. La ricostruzione della base cranica dopo resezione cranio facciale anteriore. Giorn Pat Chir Cr Fa. 1996; 2: 149–54.

23. Cantù G., Solero C.L., Pizzi N., Nardo L., Mattavelli F. Skull base reconstruction after anterior craniofacial resection. J Craniomaxillofac Surg. 1999 Aug; 27(4): 228–34. doi: 10.1016/s1010-5182(99)80034-1.

24. Eufinger H., Wehmöller M., Scholz M., Harders A., Machtens E. Reconstruction of an extreme frontal and frontobasal defect by microvascular tissue transfer and a prefabricated titanium implant. Plast Reconstr Surg. 1999; 104(1): 198–203.

25. Schuller D.R., Goodman J.H., Miller C.A. Reconstruction of the skull base. Laryngoscope. 1984; 94: 1359–64.

26. Disa J.J., Rodriguez V.M., Cordeiro P.G. Reconstruction of lateral skull base oncological defects: the role of free tissue transfer. Ann Plast Surg. 1998 Dec; 41(6): 633–9. doi: 10.1097/00000637-199812000-00009.

27. Cantu` G., Solero C.L., Pizzi N., Salvatory P., Mattavelli F. La ricostruzione della base cranica dopo resezione cranio facciale anteriore. Giorn Pat Chir Cr Fa. 1996; 2: 149–54.

28. Demirkan F., Chen H.C., Wei F.C., Chen H.H., Jung S.G., Hau S.P., Liao C.T. The versatile anterolateral thigh flap: a musculocutaneous flap in disguise in head and neck reconstruction. Br J Plast Surg. 2000 Jan; 53(1): 30–6. doi: 10.1054/bjps.1999.3250.

29. Besteiro J.M., Aki F.E., Ferreira M.C., Medina L.R., Cernea C. Free flap reconstruction of tumors involving the cranial base. Microsurgery. 1994; 15(1): 9–13. doi: 10.1002/micr.1920150105.

30. Arden R.L., Mathog R.H., Thomas L.M. Temporalis muscle-galea flap in craniofacial reconstruction. Laryngoscope. 1987 Nov; 97(11): 1336–42. doi: 10.1288/00005537-198711000-00017.

31. Janecka I.P., Sekhar L.N. Surgical management of cranial base tumors: a report on 91 patients. Oncology (Williston Park). 1989 Mar; 3(3): 69–74.

32. Smith R.R., Klopp C.T., Williams J.M. Surgical treatment of cancer of the frontal sinus and adjacent areas. Cancer. 1954 Sep; 7(5): 991–4.

33. Ketcham A.S., Wilkins R.H., Vanburen J.M., Smith R.R.A combined intracranial facial approach to the paranasal sinuses. Am J Surg. 1963 Nov; 106(5): 698–703. doi: 10.1016/0002-9610(63)90387-8.

34. Terz J.J., Young H.F., Lawrence W. Jr. Combined craniofacial resection for locally advanced carcinoma of the head and neck II. Carcinoma of the paranasal sinuses. Am J Surg. 1980 Nov; 140(5): 618–24. doi: 10.1016/0002-9610(80)90043-4.

35. Westbury G., Wilson J.S., Richardson A. Combined craniofacial resection for malignant disease. Am J Surg. 1975 Oct; 130(4): 463–9. doi: 10.1016/0002-9610(75)90485-7.

36. De Alencastro L.F., De Alencastro L.C., Martins C., Lodetti A., Cardoso A.C.C., Faria M., Inoue K., Osawa S., Rhoton A.L. Transmaxillary endscopic approach to contralateral parasellar lesions. Transnasal endoscopic skull base and brain surgery: Tips and pearls. New York: Thieme; 2011. 314 p.

37. Chepeha D.B., Wang S.J., Marentette L.J., Bradford C.R., Boyd C.M., Prince M.E., Teknos T.N. Restoration of the orbital aesthetic subunit in complex midface defects. Laryngoscope. 2004 Oct; 114(10): 1706–13. doi: 10.1097/00005537-200410000-00006.


Review

For citations:


Bolotin M.V., Mudunov A.M., Sobolevsky V.A., Gelfand I.M., Orlova I.V., Akhundov A.A. Microsurgical reconstruction of the skull base and midface after orbitomaxillary resections for malignant tumors. Siberian journal of oncology. 2021;20(6):88-95. (In Russ.) https://doi.org/10.21294/1814-4861-2021-20-6-88-95

Views: 563


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1814-4861 (Print)
ISSN 2312-3168 (Online)