ANALYSIS OF HOSPITAL MORBIDITY FOR PANCREATIC CANCER IN KRASNOYARSK KRAI
Abstract
Characteristics of hospital morbidity for pancreatic cancer among the population of Krasnoyarsky Krai between 2009 and 2013 were studied. The majority of patients (82.16 %) were diagnosed with advanced pancreatic cancer, with the incidence peak at 51–60 years and approximately equal male to female ratio. The main risk factors were overweight (in 67.66 % of patients) and diabetes (in 21.99 % of patients). The role of hereditary predisposition to the development of pancreatic cancer was not established.
About the Authors
Е. V. OkladnikovaRussian Federation
Okladnikova Evgenia Vladimirovna, MD, PhD, Associate Professor, Pharmacology Department.
E-mail: farmasis@yandex.ru. SPIN-code: 1220-9302.
Т. G. Ruksha
Russian Federation
Ruksha Tatiana Gennadievna, MD, DSc, Head of Pathophysiology Department.
E-mail: tatyana_ruksha@mail.ru. SPIN-код: 5412-2148.
References
1. Kashincev A.A., Janus G.A., Kohanenko N.Ju., Moiseenko V.M., Hanevich M.D., Roman L.D., Ievleva A.G., Sokolenko A.P., Suspicin E.N., Budovskij A.I., Togo A.V., Volkov N.M., Fadeev R.V., Dinikin M.S., Ivanova A.K., Shostko K.G., Imjanitov E.N. Occurrence of BRCA1 and BRCA2 mutation in pancreatic cancer patients / Sibirskij onkologicheskij zhurnal. 2013. № 5. P. 39–44. [in Russian]
2. Lazebnik L.B., Vinokurova L.V., Yashina N.I., Bystrovskaya Y.V., Bordin D.S., Dubtsova Y.A., Orlova Y.N. Chronic pancreatitis in the elderly – risk of pancreatic cancer // Klinicheskaja gerontologija. 2013. № 3–4. P. 14–22. [in Russian]
3. Svidinskaja M.V., Veraksich N.A. Pancreatic cancer and modern methods of surgical treatment // Sibirskij onkologicheskij zhurnal. 2013. Suppl. № 1. P. 84–85. [in Russian]
4. Status of cancer care in Russia in 2013 / Eds. A.D. Kaprin, V.V. Starinskij, G.V. Petrova. M., 2014. 235 p. [in Russian]
5. Tsaryova Ye.V., Bazin I.S. Disseminated pancreatic cancer: current treatments and new horizons // Jeffektivnaja farmakoterapija. 2013. № 24. P. 20–29. [in Russian]
6. Shtarik S.Yu., Petrova M.M., Baron I.I. Grushkina O.S., Ljubchenko O.F., Romanova I.V. Problem of obesity in adults in Krasnoyarsk (populational study) // Sibirskoe medicinskoe obozrenie. 2010. № 2. P. 53–56. [in Russian]
7. Genkinger J.M., Spiegelman D., Anderson K.E., Bernstein L., van den Brandt P.A., Calle E.E., English D.R., Folsom A.R., Freudenheim J.L., Fuchs C.S., Giles G.G., Giovannucci E., Horn-Ross P.L., Larsson S.C., Leitzmann M., Männistö S., Marshall J.R., Miller A.B., Patel A.V., Rohan T.E., Stolzenberg-Solomon R.Z., Verhage B.A., Virtamo J., Willcox B.J., Wolk A., Ziegler R.G., Smith-Warner S.A. A pooled analysis of 14 cohort studies of anthropometric factors and pancreatic cancer risk // Int. J. Cancer. 2011. Vol. 129 (7). P. 1708–1717. doi: 10.1002/ijc.25794.
8. Klint A., Engholm G., Storm H.H., Tryggvadóttir L., Gislum M., Hakulinen T., Bray F. Trends in survival of patients diagnosed with cancer of the digestive organs in the Nordic countries 1964–2003 followed up to the end of 2006 // Acta Oncol. 2010. Vol. 49 (5). P. 578–607. doi: 10.3109/02841861003739330.
9. Maisonneuve P., Lowenfels A.B. Epidemiology of pancreatic cancer: an update // Dig. Dis. 2010. Vol. 28 (4–5). P. 645–656. doi: 10.1159/000320068.
10. Raimondi S., Lowenfels A.B., Morselli-Labate A.M., Maisonneuve P., Pezzilli R. Pancreatic cancer in chronic pancreatitis; aetiology, incidence, and early detection // Best Pract. Res. Clin. Gastroenterol. 2010. Vol. 24 (3). P. 349–358. doi: 10.1016/j.bpg.2010.02.007.
11. Rückert F., Brussig T., Matthias K., Kersting S., Bunk A., Hunger M., Saeger H.-D., Niedergethmann M., Post S., Grützmann R. Malignancy in chronic pancreatitis: Analysis of diagnostic procedures and proposal of a clinical algorithm // Pancreatol. 2013. Vol. 13 (3). P. 243–249. doi: 10.1016/j.pan.2013.03.014.
12. Tingstedt B., Weitkämper C., Andersson R. Early onset pancreatic cancer: a controlled trial // Ann. Gastroenterol. 2011. Vol. 24 (3). P. 206–212.
13. Wang F., Herrington M., Jörgen L., Permert J. The relationship between diabetes and pancreatic cancer // Mol. Cancer. 2003. Vol. 6. P. 2–4.
Review
For citations:
Okladnikova Е.V., Ruksha Т.G. ANALYSIS OF HOSPITAL MORBIDITY FOR PANCREATIC CANCER IN KRASNOYARSK KRAI. Siberian journal of oncology. 2015;(6):61-67. (In Russ.)