TO THE PROBLEM OF CHOICE OF THE TREATMENT TACTICS IN METASTATIC COLORECTAL CANCE
https://doi.org/10.21294/1814-4861-2016-15-1-54-58
Abstract
Treatment outcomes of 176 colorectal cancer patients with liver metastases were retrospectivelly analyzed. There were 86 men and 90 women in the age range 28 to 84 years. Multiple metastasis was detected in 79.5 % of patients and solitary metastasis in 20.5 % of patients. Cytoreductive surgery was performed in 30.7 % of patients and palliative surgery in 57.9 %. Surgical treatment was not performed in 5.1% of patients. The median survival time of patients after symptomatic surgeries was 10.8 months (1.5-26 months). Cytoreductive surgery increased the median survival time by more than 2 months (13 months, 2–44 months). Thus, radical surgery for colorectal cancer patients with liver metastases is justified by the increase in the median survival time of the patients.
About the Authors
A. Z. Azanov
Regional Clinical Cancer Center
Russian Federation
Russian Federation
oncologist, Kemerovo;
postgraduate of the Surgery Department of Siberian State Medical University, Tomsk
A. P. Koshel
G.K. Zherlov Medical Center;
Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
Professor, Head Physician, 3, Chekist per., 636013-Seversk, Tomsk region;
Head of Surgery Department, Tomsk
S. A. Kolomiets
Regional Clinical Cancer Center
Russian Federation
Russian Federation
MD, PhD, Head Physician,
Kemerovo
O. V. Zharkova
Regional Clinical Cancer Center
Russian Federation
Russian Federation
MD, PhD, Deputy Chief Physician,
Kemerovo
S. S. Klokov
G.K. Zherlov Medical Center;
Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
MD, PhD, Deputy Chief Physician, 3, Chekist per., 636013-Seversk, Tomsk region ;
Associate Professor, Surgery Department, Tomsk
K. V. Vyalova
Regional Clinical Cancer Center
Russian Federation
Russian Federation
oncologist, Kemerovo;
postgraduate of the Surgery Department of Siberian State Medical University, Tomsk
References
1. Axel Е.М., Barmina Н.М. Colorectal cancer (morbidity, mortality, socio-economical impact) // Rossijskij onkologicheskij zhurnal. 1999. № 6. P. 40–46. [in Russian]
2. Afanas’ev S.G., Dobrodeev A.Ju. Cytoreductive surgery (Should the primary tumor be removed? (What is the optimal cytoreduction?) // Prakticheskaja onkologija. 2014. Vol. 15 (2). P. 93–100. [in Russian]
3. Cancer incidence in Russia in 2013 (morbidity and mortality) / Ed. А.D. Kaprin, V.V. Starinsky, G.V. Petrova. М., 2015. 250 p. [in Russian]
4. Kolesnik Е.А., Khvorostovsky R.R., Lavrik G.V., Gubskaya V.Z. Combined modality treatment including radical surgery and different chemotherapy regimens for colorectal cancer with synchronous liver metastases // Oncology. 2008. Vol. 10 (1). P. 155–159. [in Russian]
5. Kolomiets S.А., Eryemina N.А., Zharkova О.V. Newsletter about the structure of the oncology service, personnel, planning and economic indicators of Kuzbass cancer institutions in 2014. Health Department of the Kemerovo Region. 2015. [in Russian]
6. Conservative treatment of primary and metastatic liver cancer / Ed. V.А. Gorbunova. М., 2013. 288 p. [in Russian]
7. Kochetov А.G., Lyang О.V.., Masenko V.P., Zhirov I.V., Nakonechnikov S.N., Tereshchenko S.N. Methods of statistical data processing: Guidelines for the residents and post-graduates of medical academies and scientific reseraches. М., 2012. 42 с. [in Russian]
8. Shanazarov N.A., Mashkin А.М., Batyrbekov К.U., Midlenko А.А. Current epidemiological aspects of colorectal cancer // Science and education current challenges. 2014. № 3. URL: http://www.science-education.ru/pdf/2014/3/473.pdf. [in Russian]
9. Winawer S., Classen M., Lambert R. [et al.]. Practical World Gastroenterology Society management (WGC) and the International Union for the prevention of digestive system cancer: Colorectal cancer screening // World Gastroenterology Organisation. 2008. 18 p. [in Russian]
Review
For citations:
Azanov A.Z., Koshel A.P., Kolomiets S.A., Zharkova O.V., Klokov S.S., Vyalova K.V. TO THE PROBLEM OF CHOICE OF THE TREATMENT TACTICS IN METASTATIC COLORECTAL CANCE. Siberian journal of oncology. 2016;15(1):54-58. (In Russ.) https://doi.org/10.21294/1814-4861-2016-15-1-54-58
Views:
800
Email this article 
