ENDOSCOPIC ULTRASOUND-GUIDED RESECTION OF SOMATOSTATINOMA OF THE AMPULLA OF THE MAJOR DUODENAL PAPILLA IN THE PATIENT WITH INHERITED NEUROFIBROMATOSIS
https://doi.org/10.21294/1814-4861-2017-16-1-98-103
Abstract
Case report. We present the case of a 50-year-old female patient with inherited type 1 neurofibromatosis, who was found to have a tumor in the major duodenal papilla. She underwent endoscopic ultrasound-guided resection of the major duodenal papilla with subsequent histological and immunohistochemical examination. Discussion. Somatostatinomas are rare neuroendocrine tumors of the gastrointestinal tract with an annual incidence of 1 case per 40 million people. The combination of type 1neurofibromatosis and somatostatinoma of the ampulla of the major duodenal papilla occurs extremely rarely. Endoscopic ultrasound provides visualization of tumor spread in all layers of the intestinal wall and in the major duodenal papilla, thus giving opportunity to perform radical surgery by minimally invasive method. Conclusions. Minimally invasive endoscopic surgery in patients with a combination of type 1 neurofibromatosis and somatostatinoma is a good alternative to pancreatic resection in this rare category of patients. Further follow-up studies are needed.
About the Authors
M. M. Tavobilov
S.P. Botkin Municipal Clinical Hospital, Moscow
Russian Medical Academy for Postgraduate Education, Moscow
Russian Federation
Russian Federation
MD, PhD, Associate Professor, Surgery Department, Russian Medical Academy for Postgraduate Education; Head of Surgery Department, Botkin Hospital
SPIN-code: 9554-5553.
A. A. Karpov
S.P. Botkin Municipal Clinical Hospital, Moscow
Russian Federation
Russian Federation
MD, Surgeon, Surgery Department, Botkin Hospital
SPIN-code: 9877-4166
I. Yu. Korzheva
S.P. Botkin Municipal Clinical Hospital, Moscow
Russian Medical Academy for Postgraduate Education, Moscow
Russian Federation
MD, DSc, Professor, Endoscopy Department, Russian Medical Academy for Postgraduate Education; Head of Endoscopy Department, Botkin Hospital
Russian Federation
MD, DSc, Professor, Endoscopy Department, Russian Medical Academy for Postgraduate Education; Head of Endoscopy Department, Botkin Hospital
O. V. Paklina
S.P. Botkin Municipal Clinical Hospital, Moscow
Russian Federation
Russian Federation
MD, DSc, Head of the Pathology Department, Botkin Hospital
SPIN-code: 4575-9762
G. R. Setdikova
S.P. Botkin Municipal Clinical Hospital, Moscow
Russian Federation
Russian Federation
MD, PhD, Department of Pathology, Botkin Hospital
SPIN-code: 6551-0854.
A. V. Shabunin
S.P. Botkin Municipal Clinical Hospital, Moscow
Russian Medical Academy for Postgraduate Education, Moscow
Russian Federation
Russian Federation
MD, DSc, Professor, Corresponding Member of the Russian Academy of Sciences, Head of Department of the Surgery, Russian Medical Academy for Postgraduate Education; Chief Physician, Botkin Municipal Hospital
SPIN-code: 8917-7732
V. V. Bedin
S.P. Botkin Municipal Clinical Hospital, Moscow
Russian Medical Academy for Postgraduate Education, Moscow
Russian Federation
MD, PhD, Associate Professor, Surgery Department, Russian Medical Academy for Postgraduate Education; Head of the Surgery Department, Botkin Municipal Hospital
Russian Federation
MD, PhD, Associate Professor, Surgery Department, Russian Medical Academy for Postgraduate Education; Head of the Surgery Department, Botkin Municipal Hospital
M. S. Burdyukov
S.P. Botkin Municipal Clinical Hospital, Moscow
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
MD, PhD, Associate Professor, Endoscopy Department, Russian Medical Academy for Postgraduate Education; Senior Researcher, N.N. Blokhin Russian Cancer Research Center
Russian Federation
MD, PhD, Associate Professor, Endoscopy Department, Russian Medical Academy for Postgraduate Education; Senior Researcher, N.N. Blokhin Russian Cancer Research Center
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Review
For citations:
Tavobilov M.M., Karpov A.A., Korzheva I.Yu., Paklina O.V., Setdikova G.R., Shabunin A.V., Bedin V.V., Burdyukov M.S. ENDOSCOPIC ULTRASOUND-GUIDED RESECTION OF SOMATOSTATINOMA OF THE AMPULLA OF THE MAJOR DUODENAL PAPILLA IN THE PATIENT WITH INHERITED NEUROFIBROMATOSIS. Siberian journal of oncology. 2017;16(1):98-103. (In Russ.) https://doi.org/10.21294/1814-4861-2017-16-1-98-103
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