REPEATED OPTIMAL CYTOREDUCTIVE SURGERIES IN COMBINED MODALITY TREATMENT OF OVARIAN CANCER. CASE REPORT
https://doi.org/10.21294/1814-4861-2017-16-3-99-103
Abstract
To date, the algorithm for the treatment of recurrent ovarian cancer and the criteria for selecting patients for performing secondary cytoreductive surgeries have not been fully developed. Although the role of secondary surgery in recurrent ovarian cancer remains controversial, most retrospective studies showed better survival in patients for whom maximal cytoreduction was achieved. Several studies have developed prognostic models for the feasibility of performing complete secondary cytoreduction. We report a rare case of repeated cytoreductive surgeries in combination with chemotherapy for recurrent ovarian cancer. This clinical case indicates the feasibility of performing repeated cytoreductive surgeries in patients with localized recurrent ovarian cancer undergoing previous optimal cytoreductions and having no ascites.
About the Authors
S. V. Molchanov
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
MD, PhD, Department of Gynecology
SPIN-code: 2719-3289
5, Kooperativny str., 634009-Tomsk
L. A. Kolomiets
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
MD, DSc, Professor, Head of the Department of Gynecology
SPIN-code: 6316-1146
5, Kooperativny str., 634009-Tomsk
O. V. Shpilyeva
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
MD, Researcher, Department of Gynecology
SPIN-code: 1441-0681
5, Kooperativny str., 634009-Tomsk
References
1. Davydov М.I., Axel Е.М. Statistics of cancer in Russia and CIS countries in 2012. 2014; 226. [in Russian]
2. Ferrero A., Ditto A., Giorda G., Gadducci A., Greggi S., Daniele A., Fuso L., Panuccio E., Scaffa C., Raspagliesi F., Sismondi P., Biglia N. Secondary cytoreductive surgery for isolated lymph node recurrence of epithelial ovarian cancer: A multicenter study. Eur J Surg Oncol. 2014; 40: 891–8. doi: 10.1016/j.ejso.2013.11.026.
3. Chuang C.M., Chou Y.J., Yen M.S., Chao K.C., Twu N.F., Wu H.H., Wen K.C., Chen Y.J., Wang P.H., Lai C.R., Chou P. The Role of Secondary Cytoreductive Surgery in Patients with Recurrent Epithelial Ovarian, Tubal, and Peritoneal Cancers: A Comparative Effectiveness Analysis. Oncologist. 2012; 17: 847–855. doi: 10.1634/theoncologist.2011-0373.
4. Afanasyev S.G., Dobrodeev A.Ju. Cytoreductive surgery (Should the primary tumor be removed? (What is the optimal cytoreduction?). Practical oncology. 2014; 15 (2): 93–100. [in Russian]
5. Bristow R.E., Puri I., Chi D.S. Cytoreductive surgery for recurrent ovarian cancer: a meta-analysis. Gynecol Oncol. 2009; 112: 265–274.
6. Harter P., Du Bois A., Hahmann M., Hasenburg A., Burges A., Loibl S., Muenstedt K. Surgery in recurrent ovarian cancer: the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) DESKTOP OVAR trial. Ann Surg Oncol. 2006; 13: 1702–1710.
7. Harter P., Sehouli J., Reuss A., Hasenburg A., Scambia G., Cibula D., Hanker L. Prospective validation study of a predictive score for operability of recurrent ovarian cancer: the Multicenter Intergroup Study DESKTOP II. A project of the AGO Kommission OVAR, AGO Study Group, NOGGO, AGO-Austria, and MITO. Int J Gynecol Cancer. 2011; 21: 289–295. doi: 10.1097/IGC.0b013e31820aaafd.
8. Tian W.J., Chi D.S., Sehouli J., Tropé C.G., Jiang R., Ayhan A., Rabbitt C.A. A risk model for secondary Cytoreductive surgery in recurrent ovarian cancer: an evidence-based proposal for patient selection. Ann Surg Oncol. 2012; 19: 597–604. doi: 10.1245/s10434-011-1873-2.
9. Sammartino P., Cornali T., Framarino dei Malatesta M., Piso P. Cytoreductive surgery after recurrent epithelial ovarian cancer and at other timepoints. World J Obst Gynecol. 2013; 2: 101–107. doi: 10.5317/ wjog.v2.i4.10.
10. Eisenkop S.M., Friedman R.L., Spirtos N.M. The role of secondary surgery in recurrent ovarian cancer. Cancer. 2012;, 88 (1): 144–153.
Review
For citations:
Molchanov S.V., Kolomiets L.A., Shpilyeva O.V. REPEATED OPTIMAL CYTOREDUCTIVE SURGERIES IN COMBINED MODALITY TREATMENT OF OVARIAN CANCER. CASE REPORT. Siberian journal of oncology. 2017;16(3):99-103. (In Russ.) https://doi.org/10.21294/1814-4861-2017-16-3-99-103
Views:
1011
Email this article 
