THYMOMA (REVIEW OF THE LITERATURE)
https://doi.org/10.21294/1814-4861-2017-16-4-76-83
Abstract
Objective. We aimed to systematically review the literature dealing with the epidemiology, classification, clinical course, diagnosis and treatment of thymoma. Material and methods. We reviewed retrospective and prospective randomized trials using Medline and Elibrary databases. Results. The classification system, prognostic factors, paraneoplastic syndromes and their incidence in patients with thyoma were described. The diagnostic value of computed tomography, magnetic resonance imaging and positron emission tomography was evaluated and the methods of morphologic verification were described. The main attention was paid to multimodality treatment of thymoma, including surgery and intraoperative radiotherapy. Conclusion. Thymoma is a rare tumor. The accumulation of long-term follow-up results prompted the changes in clinical management of thymoma. Predisposition to late recurrence even after radical surgery determined multimodality treatment strategies.
About the Authors
O. A. Alexandrov
Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.
Russian Federation
Russian Federation
Alexandrov Oleg A., Clinical Resident, Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.
3, Botkinsky proezd 2-nd, 125284-Moscow, Russia.
A. B. Ryabov
Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.
Russian Federation
Russian Federation
Ryabov Andrey B., MD, DSc, Professor, Head of Thoracic and Abdominal Surgery, Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.
3, Botkinsky proezd 2-nd, 125284-Moscow, Russia.
O. V. Pikin
Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.
Russian Federation
Russian Federation
Pikin Oleg V., MD, DSc, Professor, Head of Thoracic Surgery, Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.
3, Botkinsky proezd 2-nd, 125284-Moscow, Russia.
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Review
For citations:
Alexandrov O.A., Ryabov A.B., Pikin O.V. THYMOMA (REVIEW OF THE LITERATURE). Siberian journal of oncology. 2017;16(4):76-83. (In Russ.) https://doi.org/10.21294/1814-4861-2017-16-4-76-83
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