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EFFECT OF FENUGREEK ON THE LEVEL OF MALONE DIALDEHYDE AND CERTAIN HEMATOLOGIC PARAMETERS IN TUMOR-BEARING ANIMALS

Abstract

This paper deals with effect of fenugreek on the level of malone dialdehyde and certain hematologic parameters in animals with grafted Ca755 mammary carcinoma, L1210 lymphoid leukemia and Guerin carcinoma substrains, resistant to doxorubicin and cisplatin. Fenugreek consumption was shown to amend hematologic parameters and decrease level of malone dialdehyde in liver (32–63 %), kidney (21 %) and heart (33 %) in animals with different genesis tumors. Thus, these results show that fenugreek can be a potential antioxidant agent.

About the Authors

V. V. Zhylenko
Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology NAS of Ukraine, Kyiv, Ukraine
Russian Federation


S. P. Zaletok
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology NAS of Ukraine, Kyiv, Ukraine
Russian Federation


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Review

For citations:


Zhylenko V.V., Zaletok S.P. EFFECT OF FENUGREEK ON THE LEVEL OF MALONE DIALDEHYDE AND CERTAIN HEMATOLOGIC PARAMETERS IN TUMOR-BEARING ANIMALS. Siberian journal of oncology. 2013;(2):58-61. (In Russ.)

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ISSN 1814-4861 (Print)
ISSN 2312-3168 (Online)