ASSESSMENT OF THE EFFICTIVENESS OF EPIDURAL ANESTHESIA IN TREATMENT OF RECTAL CANCER
Abstract
The comparative analysis of the efficacy of anesthetic management in 53 patients with operable rectal cancer was carried out. In the study group patients (n=29), preemptive thoracic epidural analgesia was used. In the control group, (n=24), anesthesia was induced with sevofluorane and fentanyl. Preemptive thoracic epidural analgesia provided a reliable blockade of nociceptors and neural pathways, normalized stress response and decreased the severity of the systemic inflammatory response by stimulating the production of antiinflammatory cytokines.
About the Authors
S. V. Avdeev
Tomsk Cancer Research Institute, Tomsk
Russian Federation
Russian Federation
Avdeev Sergej Veniaminovich - MD, DSc., Head of the Department of Anesthesiology and Resuscitation.
E-mail: serg_avdeev@mail.ru
S. G. Afanasyev
Tomsk Cancer Research Institute, Tomsk
Russian Federation
Russian Federation
Afanasjev Sergey Gennadjevich - MD, DSc., Leading researcher, Thoracal and Abdominal Department.
E-mail: AfanasievSG@oncology.tomsk.ru
S. I. Savosina
Tomsk Cancer Research Institute, Tomsk; Kemerovo Regional Cancer Center, Kemerovo
Russian Federation
Savosina Svetlana Igorevna
Russian Federation
Savosina Svetlana Igorevna
V. V. Faltin
Tomsk Cancer Research Institute, Tomsk
Russian Federation
Faltin Vladimir Vladimirovich - Junior Researcher, Department of Anesthesiology and Resuscitation
Russian Federation
Faltin Vladimir Vladimirovich - Junior Researcher, Department of Anesthesiology and Resuscitation
L. V. Gerdt
Tomsk Cancer Research Institute, Tomsk
Russian Federation
Russian Federation
Gerdt Ljubov Viktorovna - MD., PhD., physician assistant, Laboratory of Molecular Oncology and Immunology.
E-mail: immun@ oncology.tomsk.ru
M. N. Stakheeva
Tomsk Cancer Research Institute, Tomsk
Russian Federation
Russian Federation
Stakheeva Marina Nikolaevna - MD, DSc., Senior Researcher, Laboratory of Molecular Oncology and Immunology.
E-mail: StakheyevaM@oncology.tomsk.ru
S. A. Tuzikov
Tomsk Cancer Research Institute, Tomsk; Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
Tuzikov Sergey Aleksandrovich - MD, DSc., Professor, Head of The Thoracal and Abdominal Department
E-mail: TuzikovSA@oncology.tomsk.ru
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Review
For citations:
Avdeev S.V., Afanasyev S.G., Savosina S.I., Faltin V.V., Gerdt L.V., Stakheeva M.N., Tuzikov S.A. ASSESSMENT OF THE EFFICTIVENESS OF EPIDURAL ANESTHESIA IN TREATMENT OF RECTAL CANCER. Siberian journal of oncology. 2015;1(2):39-45. (In Russ.)
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