CHONDROID LIPOMA AS SOFT TISSUE PSEUDOSARCOMA: LITERATURE REVIEW AND CASE REPORT
https://doi.org/10.21294/1814-4861-2021-20-4-152-159
Abstract
Background. Pseudosarcomas of soft tissues can cause diagnostic and treatment challenges. On the one hand, it is difficult to make a nosological diagnosis based on a biopsy specimen of a tumor; on the other hand, it is difficult to determine the most appropriate treatment strategy based on a histological pattern.
The purpose of the study was to analyze available literature data and systematize the histological characteristics of the chondroid lipoma and pseudosarcoma.
Case description. We present the case of chondroid lipoma in a 57-year-old female patient with atypical clinical symptoms. This case shows the difficulties of differential diagnosis of soft tissue sarcomas. Using a clinical example of chondroid lipoma, a rare soft tissue tumor, and an analysis of literature data, the authors showed the importance of a detailed study of the obtained material, a qualified description of the morphological picture, in those cases when the diagnostic conclusion cannot be unambiguous about the malignancy of the tumor process. Additional biopsy is not always possible to clarify the histotype of the tumor. The presented observation shows the difficulties of differential diagnosis of soft tissue sarcomas. Minimally invasive biopsy provides no a full appreciation of histological structure; therefore, if there is a suspicion for chondroid lipoma, it is necessary to perform total surgical biopsy followed by a morphological study using the immunohistochemical method.
About the Authors
N. V. VasilyevRussian Federation
MD, PhD, Senior Researcher, Department of General and Molecular Pathology
Researcher ID (WOS): D-1144-2012. Author ID (Scopus): 57192110276
5, Kooperativny Street, 634050, Tomsk, Russia
S. V. Vtorushin
Russian Federation
MD, DSc, Head of Department of General and Molecular Pathology; Professor of Pathology Department
Researcher ID (WOS): S-3789-2016. Author ID (Scopus): 26654562300
5, Kooperativny Street, 634050, Tomsk, Russia
2, Moskovsky Trakt, 634050, Tomsk, Russia
I. I. Anisenya
Russian Federation
MD, PhD, Senior Researcher, Department of General Oncology
Researcher ID (WOS): D-8434-2012. Author ID (Scopus): 57192110276
5, Kooperativny Street, 634050, Tomsk, Russia
P. K. Sitnikov
Russian Federation
MD, Oncologist, Department of General Oncology
5, Kooperativny Street, 634050, Tomsk, Russia
S. A. Tabakaev
Russian Federation
MD, Postgraduate, Imaging Department
5, Kooperativny Street, 634050, Tomsk, Russia
I. G. Frolova
Russian Federation
MD, Professor, Head of Imaging Department
Author ID (Scopus): 700641170. Researcher ID (WOS): С-8212-2012
5, Kooperativny Street, 634050, Tomsk, Russia
A. V. Bogoutdinova
Russian Federation
MD, PhD, Oncologist, Department of General Oncology
5, Kooperativny Street, 634050, Tomsk, Russia
L. D. Zhuikova
Russian Federation
MD, PhD
Researcher ID (WOS): C-8293-2012. Author ID (Scopus): 56626111900
115, Lenina Prospekt, 634050, Tomsk, Russia
P. V. Bairamov
Russian Federation
MD, Pathologist
173, Tsukanova Street, 655009, Abakan, Russia
S. I. Ponomareva
Russian Federation
Student
Researcher ID (WOS): AAP-2316-2020
2, Moskovsky Trakt, 634050, Tomsk, Russia
M. O. Tsvetukhin
Russian Federation
Student
2, Moskovsky Trakt, 634050, Tomsk, Russia
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Review
For citations:
Vasilyev N.V., Vtorushin S.V., Anisenya I.I., Sitnikov P.K., Tabakaev S.A., Frolova I.G., Bogoutdinova A.V., Zhuikova L.D., Bairamov P.V., Ponomareva S.I., Tsvetukhin M.O. CHONDROID LIPOMA AS SOFT TISSUE PSEUDOSARCOMA: LITERATURE REVIEW AND CASE REPORT. Siberian journal of oncology. 2021;20(4):152-159. (In Russ.) https://doi.org/10.21294/1814-4861-2021-20-4-152-159