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CHONDROID LIPOMA AS SOFT TISSUE PSEUDOSARCOMA: LITERATURE REVIEW AND CASE REPORT

https://doi.org/10.21294/1814-4861-2021-20-4-152-159

Abstract

Background. Pseudosarcomas of soft tissues can cause diagnostic and treatment challenges. On the one hand, it is difficult to make a nosological diagnosis based on a biopsy specimen of a tumor; on the other hand, it is difficult to determine the most appropriate treatment strategy based on a histological pattern.

The purpose of the study was to analyze available literature data and systematize the histological characteristics of the chondroid lipoma and pseudosarcoma.

Case description. We present the case of chondroid lipoma in a 57-year-old female patient with atypical clinical symptoms. This case shows the difficulties of differential diagnosis of soft tissue sarcomas. Using a clinical example of chondroid lipoma, a rare soft tissue tumor, and an analysis of literature data, the authors showed the importance of a detailed study of the obtained material, a qualified description of the morphological picture, in those cases when the diagnostic conclusion cannot be unambiguous about the malignancy of the tumor process. Additional biopsy is not always possible to clarify the histotype of the tumor. The presented observation shows the difficulties of differential diagnosis of soft tissue sarcomas. Minimally invasive biopsy provides no a full appreciation of histological structure; therefore, if there is a suspicion for chondroid lipoma, it is necessary to perform total surgical biopsy followed by a morphological study using the immunohistochemical method.

About the Authors

N. V. Vasilyev
Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

 MD, PhD, Senior Researcher, Department of General and Molecular Pathology 

Researcher ID (WOS): D-1144-2012. Author ID (Scopus): 57192110276 

5, Kooperativny Street, 634050, Tomsk, Russia



S. V. Vtorushin
Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical University
Russian Federation

 MD, DSc, Head of Department of General and Molecular Pathology; Professor of Pathology Department

Researcher ID (WOS): S-3789-2016. Author ID (Scopus): 26654562300 

5, Kooperativny Street, 634050, Tomsk, Russia

2, Moskovsky Trakt, 634050, Tomsk, Russia



I. I. Anisenya
Cancer Research Institute, Tomsk National Research edical Center, Russian Academy of Sciences
Russian Federation

 MD, PhD, Senior Researcher, Department of General Oncology

Researcher ID (WOS): D-8434-2012. Author ID (Scopus): 57192110276 

5, Kooperativny Street, 634050, Tomsk, Russia

 



P. K. Sitnikov
Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences 
Russian Federation

 MD, Oncologist, Department of General Oncology

5, Kooperativny Street, 634050, Tomsk, Russia



S. A. Tabakaev
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences 
Russian Federation

 MD, Postgraduate, Imaging Department

5, Kooperativny Street, 634050, Tomsk, Russia

 



I. G. Frolova
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences
Russian Federation

 MD, Professor, Head of Imaging Department

Author ID (Scopus): 700641170. Researcher ID (WOS): С-8212-2012 

5, Kooperativny Street, 634050, Tomsk, Russia



A. V. Bogoutdinova
Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences 
Russian Federation

 MD, PhD, Oncologist, Department of General Oncology

5, Kooperativny Street, 634050, Tomsk, Russia



L. D. Zhuikova
Clinical Statistician, Tomsk Regional Oncology Center
Russian Federation

 MD, PhD

Researcher ID (WOS): C-8293-2012. Author ID (Scopus): 56626111900 

115, Lenina Prospekt, 634050, Tomsk, Russia



P. V. Bairamov
Republic Clinical Cancer Center
Russian Federation

 MD, Pathologist

173, Tsukanova Street, 655009, Abakan, Russia



S. I. Ponomareva
Siberian State Medical University
Russian Federation

 Student

Researcher ID (WOS): AAP-2316-2020 

2, Moskovsky Trakt, 634050, Tomsk, Russia



M. O. Tsvetukhin
Siberian State Medical University
Russian Federation

 Student

2, Moskovsky Trakt, 634050, Tomsk, Russia



References

1. Huang C., Guo W., Qu W., Zhu Z., Li R. Characteristics of chondroid lipoma: A case report and literature review. Medicine (Baltimore). 2019 May; 98(19): e15587. doi: 10.1097/MD.0000000000015587.

2. Jo V.Y., Hornick J.L. Neoplastic mimics in soft tissue and bone pathology. DiacriTech. LLC, 2016. 363 р.

3. Goldblum J.R., Folpe A.L., Weiss S.W. Enzinger and Weiss”s Soft tissue tumors. Sixth edition. MOSBY Elsevier. 2014. 1155 p.

4. Folpe A.L., Inwards C.Y. Bone and soft tissue pathology (A volume in the series foundations in diagnostic pathology). By Saunders, an imprint of Elsevier, Inc. 2010. 462 р.

5. Hornick J.L. Practical soft tissue pathology. A diagnostic approach. 2013. by Saunders, an imprint of Elsevier Inc. 523 р.

6. Meis J.M., Enzinger F.M. Chondroid lipoma. A unique tumor simulating liposarcoma and myxoid chondrosarcoma. Am J Surg Pathol. 1993 Nov; 17(11): 1103–12.

7. Thway K., Flora R.S., Fisher C. Chondroid lipoma: an update and review. Ann Diagn Pathol. 2012 Jun; 16(3): 230–4. doi: 10.1016/j.anndiagpath.2012.01.002.

8. Villarroel Dorrego M., Papp Y., Shelley M.J., Barrett A.W. Chondroid lipoma of the tongue: a report of two cases. Oral Maxillofac Surg. 2014 Jun; 18(2): 219–22. doi: 10.1007/s10006-013-0426-1.

9. Fletcher C.D.M., Bridge J.A., Hogendoorn P.C.W., Mertens F. WHO Classification of Tumours of Soft Tissue and Bone. IARC: Lyon 2013. 468 р.

10. Perez-Ordonez B., Chetty R. Chondroid lipoma of the parotid gland. Diagnostic Histopathology. 2014; 20(10): 422–424.

11. Guillou L., Fletcher C.D.M. Newer entities in soft tissue tumours. Current Diagnostic Pathology. 1997; 4: 210–221.

12. Murphey M.D., Carroll J.F., Flemming D.J., Pope T.L., Gannon F.H., Kransdorf M.J. From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics. 2004 Sep-Oct; 24(5): 1433–66. doi: 10.1148/rg.245045120.

13. Stanford University Medical Center. School of medicine. Surgical Pathology Criteria is focused on the presentation of useful diagnostic criteria in an accessible format. Soft tissue – tumors of adipose differentiation. 2017. [Internet]. URL: https://surgpathcriteria.stanford.edu/by_section.html#Fat. (cited 16.08.2020).

14. Mills S.E. Sternberg’s diagnostic surgical pathology, 5th edition. Lippincott Williams & Wilkins. 2010. 2785.

15. Forcucci J.A., Bruner E.T., Smith M.T. Benign soft tissue lesions that may mimic malignancy. Semin Diagn Pathol. 2016 Jan; 33(1): 50–9. doi: 10.1053/j.semdp.2015.09.007.

16. Rosenberg A.E. Pseudosarcomas of soft tissue. Arch Pathol Lab Med. 2008 Apr; 132(4): 579–86. doi: 10.5858/2008-132-579-POST.

17. Bishop J.A. Soft Tissue Pseudosarcomas. Surg Pathol Clin. 2011 Sep; 4(3): 699–719. doi: 10.1016/j.path.2011.08.001.


Review

For citations:


Vasilyev N.V., Vtorushin S.V., Anisenya I.I., Sitnikov P.K., Tabakaev S.A., Frolova I.G., Bogoutdinova A.V., Zhuikova L.D., Bairamov P.V., Ponomareva S.I., Tsvetukhin M.O. CHONDROID LIPOMA AS SOFT TISSUE PSEUDOSARCOMA: LITERATURE REVIEW AND CASE REPORT. Siberian journal of oncology. 2021;20(4):152-159. (In Russ.) https://doi.org/10.21294/1814-4861-2021-20-4-152-159

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ISSN 1814-4861 (Print)
ISSN 2312-3168 (Online)