FAST NEUTRON THERAPY: A STATUS REPORT
About the Authors
F. M. WagnerGermany
Research neutron source FRM II
H. Specht
Germany
Research neutron source FRM II
B. Loeper-Kabasakal
Germany
Research neutron source FRM II, Research neutron source FRM II
H. Breitkreutz
Germany
Research neutron source FRM II
References
1. Auberger T., Reuschel W. The Role of Fast Neutrons in the Treatment of Squamous Cell Carcinomas of Head and Neck: The European Experience // Recent Results in Cancer Research Vol. 150. Springer-Verlag Berlin, Heidelberg, 1998.
2. Auberger T., Reuschel W., Kneschaurek P., Wehrmann R., Wagner F.M., Lukas P., Molls M. Reactor Neutron Therapy of Locally Recurrent Breast Cancer // Progress in RadioOncology V / Ed. H.D. Kogelnik. Monduzzi Editore Bologna, 1995. P. 691–694.
3. Breitkreutz H., Wagner F.M., Röhrmoser A., Petry W. Spectral fluence rates of the fast reactor neutron beam MedApp at FRM II // Nucl. Instr. Methods. 2008. Vol. 593. P. 466–471.
4. Bremer M., Neuhofer C., Zimmermann F., Kneschaurek P., Reuschel W., Molls M. Palliative radiotherapy of malignant melanoma with reactor fission neutron therapy (RENT): a prospective study // Radiat. Oncol. Investig. 1999. Vol. 7 (2). P. 118–124.
5. Jungwirth M., Breitkreutz H., Wagner F M., Bücherl T. Determination of the photon spectrum in an intense fission neutron beam // J. of Instrumentation. 2012. Vol. 7. C. 03022. (8 pages). doi:10.1088/1748-0221/7/03/C03022.
6. Kampfer S., Wagner F. M., Loeper B., Kneschaurek P. Erste dosimetrische Ergebnisse an der neuen Neutronentherapieanlage am FRM II // Medizinische Physik. 2006. Vol. 37. P. 318–319.
7. Koester L. Applicability of Reactor Fission Neutrons for Radiation Therapy of Cancer // Nuclear Science Applications. 1984. Vol. 2. P. 79–96.
8. Kummermehr J., Schraube H., Ries G., Koester L., Höver K.-H., Blattmann H., Stas P., Burger G. Biological effectiveness of neutrons and pi-mesons in gut, bone, and transplantable tumours // Strahlenther. Onkol. 1989. Vol. 165 (4). P. 276–282.
9. Magaddino V., Wagner F.M., Kummermehr J. Preclinical Screening of the Biological Effectiveness of a Therapeutic Neutron Beam at the FRM II // Exp. Strahlenther. Klin. Strahlenbiol. 2007. Vol. 16. P. 129–131.
10. Ries G., Breit A., Kummermehr J., Breiter N., Trott K.-R. The RENT Project: Radiobiological Results and Planned Clinical Application // Strahlentherapie. 1985. Vol. 161 (12). P. 791–793.
11. Schmid E., Wagner F.M., Romm H., Walsh L., Roos H. Doseresponse relationship of dicentric chromosomes in human lymphocytes obtained for the fission neutron therapy facility MEDAPP at the research reactor FRM II // Radiat. Environ Biophys 2009. Vol. 48 (1). P. 67–75. doi: 10.1007/s00411-008-0202-z.
12. Wagner F.M., Bücherl Th., Kampfer S., Kastenmüller A., Waschkowski W. Thermal Neutron Converter for Irradiations with Fission Neutrons // Nuclear Physics and Atomic Energy. 2007. Nr. 3 (21). P. 30–36.
13. Wagner F.M., Kneschaurek P., Kampfer S., Kastenmüller A., Loeper-Kabasakal B., Waschkowski W., Breitkreutz H., Molls M., Petry W. The Munich Fission Neutron Therapy Facility MEDAPP at the Research Reactor FRM II // Strahlenther. Onkol. 2008. Vol. 184 (12). P. 643–646. doi: 10.1007/s00066-008-1878-3.
14. Wagner F.M., Loeper-Kabasakal B., Breitkreutz H. Neutron medical treatment of tumours – a survey of facilities // J. of Instrumentation. 2012. Vol. 7. C. 03041 (14 pages). doi:10.1088/1748-0221/7/03/C03041
Review
For citations:
Wagner F.M., Specht H., Loeper-Kabasakal B., Breitkreutz H. FAST NEUTRON THERAPY: A STATUS REPORT. Siberian journal of oncology. 2015;(6):5-12. (In Russ.)