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Rare case of primary hepatoid adenocarcinoma of the lung

https://doi.org/10.21294/1814-4861-2022-21-2-150-155

Abstract

Hepatoid adenocarcinoma is a rare type of adenocarcinoma with hepatocellular differention, which is characterized by early metastatic spread and poor prognosis. The treatment strategy in not clearly defined due to an extreme rarity of the tumor. Surgery is the most effective tool as a part of multimodality concept. So far, only 51 cases have been described in the literature, and only one in Russia.

Clinical case description. We report a case of metastatic hepatoid adenocarcinoma of the lung in a 54-year-old male patient. The difficulties in morphologic differential diagnosis between adenocarcinoma of the lung and primary liver cancer were described. The strategy for managing patients with hepatoid adenocarcinoma of the lung was demonstrated.

Conclusion. Hepatoid adenocarcinoma of the lung is a rare tumor with unfavourable outcome.

About the Authors

E. A. Toneev
Regional Clinical Oncological Dispensary; Ulyanovsk State University
Russian Federation

 MD, Surgeon, Thoracic Surgery Department; Assistant, Surgery Department, Institute of Medicine, Ecology and Physical Culture

90, September 12 Str., 432017, Ulyanovsk, Russia

42, Leo Tolstoy Str., 432017, Ulyanovsk, Russia



A. A. Martynov
Regional Clinical Oncological Dispensary 
Russian Federation

 MD, Head of Thoracic Surgery Department

90, September 12 Str., 432017, Ulyanovsk, Russia



M. M. Lazarevsky
Regional Clinical Oncological Dispensary 
Russian Federation

 MD, Head of Pathomorphology Department 

90, September 12 Str., 432017, Ulyanovsk, Russia



O. V. Pikin
P.A. Herzen Moscow Research Institute of Oncology – branch of National Medical Research Center for Radiology of the Ministry of Health of Russia 
Russian Federation

 MD, DSc, Head of Thoracic Surgery Department

3, 2nd Botkinsky Ave., 125284, Moscow, Russia



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Review

For citations:


Toneev E.A., Martynov A.A., Lazarevsky M.M., Pikin O.V. Rare case of primary hepatoid adenocarcinoma of the lung. Siberian journal of oncology. 2022;21(2):150-155. (In Russ.) https://doi.org/10.21294/1814-4861-2022-21-2-150-155

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ISSN 1814-4861 (Print)
ISSN 2312-3168 (Online)