Experience of treating late cerebral lungcancer metastasis using photodynamic therapy
Abstract
Treatment outcomes for a patient with solitary brain metastasis after long-term relapse-free follow-up of invasive lung carcinoma were presented. Brain metastasis without other signs of disease progression was diagnosed 10 years after combined modality treatment for stage II lung cancer. Removal of intracerebral metastasis with intraoperative photodynamic therapy was performed. Histology microspecimens of the primary tumor and metastasis were similar. No signs of disease progression in the brain 9 months after surgery were found. This case demonstrates that it is important to increase cancer suspicion for patients with long-term relapse-free follow-up. The use of intraoperative photodynamic therapy with photoditazine as a sensitizer in the treatment of cerebral metastases results in a favorable anti-tumor effect, thus improving life quality of patients
About the Authors
A. I. Ryabova
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
V. A. Novikov
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
A. A. Zavyalov
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk, Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
A. Yu. Dobrodeev
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
S. A. Gluschenko
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
V. M. Perelmuter
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk, Siberian State Medical University, Tomsk
Russian Federation
Russian Federation
I. G. Frolova
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
E. E. Bober
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
P. L. Surkova
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
K. Yu. Menshikov
Cancer Research Institute, Siberian Branch of the Russian Academy of Medical Sciences, Tomsk
Russian Federation
Russian Federation
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Review
For citations:
Ryabova A.I., Novikov V.A., Zavyalov A.A., Dobrodeev A.Yu., Gluschenko S.A., Perelmuter V.M., Frolova I.G., Bober E.E., Surkova P.L., Menshikov K.Yu. Experience of treating late cerebral lungcancer metastasis using photodynamic therapy. Siberian journal of oncology. 2013;(5):66-69. (In Russ.)
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