Preview

Siberian journal of oncology

Advanced search

FORMATION OF OBTURATOR APPARATUS IN LOWER UTERINE SEGMENT IN PATIENTS WITH INVASIVE CERVICAL CANCER AFTER RADICAL TRANSABDOMINAL TRACHELECTOMY

Abstract

A need to strengthen the lower uterine segment and the formation of «obturator» apparatus for carrying a subsequent pregnancy is one of the problems of transabdominal radical trachelectomy performed for patients with stage IA2–IB2 cervical cancer. Isthmo-cervical incompetence may lead to mechanical falling and prolapse of the fetal bladder, creating conditions for its infection. We have developed and tested a method for forming the obturator apparatus of the uterus at the level of the internal os. Usefulness of the mesh implant made of a superelastic titanium nickelid is due to its unique biomechanical properties and high biocompatibility. Regarding the problem of strengthening the utero-vaginal anastomosis, the implant takes over the basic function of the «obturator» apparatus of the uterus, providing functional support, and formed anastomosis to change intrauterine and intraperitoneal pressure.

About the Authors

А. L. Chernyshova
Tomsk Cancer Research Institute National Research Tomsk Polytechnic University
Russian Federation
5, Kooperativny Street, 634050-Tomsk


L. А. Kolomiets
Tomsk Cancer Research Institute Siberian State Medical University, Tomsk
Russian Federation


V. E. Gyunter
Research Institute of Medical Materials and Shape Memory Implants, Томск
Russian Federation


Т. L. Chekalkin
Research Institute of Medical Materials and Shape Memory Implants, Томск
Russian Federation


References

1. Adamjan L.V., Zhordanija K.I., Beloborodov S.M. Reproductive function in cancer patients. How to maintain ability to have children? // 2004. Vol. 50 (3). P. 279–292. [in Russian]

2. Antipov V.A., Novikova E.G., Balahonceva O.S., Shevchuk A.S. Functional and anatomic rehabilitation after radical abdominal trachelectomy // Problemy reprodukcii. 2010. № 1. P. 103–107. [in Russian]

3. Antipov V.A., Novikova E.G., Balahonceva O.S., Shevchuk A.S. Radical abdominal trachelectomy: technical aspects // Voprosy onkologii. 2010. Vol. 56 (1). P. 36–42. [in Russian]

4. Bochkareva N.V., Kondakova I.V., Kolomiec L.A., Chernyshova A.L. Insulin-like growth factors and insulin-like growth factor binding proteins in pathogenesis of endometrial cancer // Sibirskij onkologicheskij zhurnal. 2008. № 3. [in Russian]

5. Medical materials and implants with shape memory: in 14 volumes // Ed. V.Je. Gjunter. Tomsk, 2013. Vol. 13. P. 277–287. [in Russian]

6. Novikova E.G., Antipov V.A., Ronina E.A., Balahonceva O.S. Radical abdominal trachelectomy // Rossijskij onkologicheskij zhurnal. 2010. № 1. P. 8–14. [in Russian]

7. Chernyshova A.L., Ljapunov A.Ju., Kolomiec L.A., Chernov V.I., Sinilkin I.G. Detection of sentinel lymph nodes in surgical treatment of cervical cancer // Sibirskij onkologicheskij zhurnal. 2012. № 3. P. 28–33. [in Russian]

8. Chernyshova A.L., Kolomiec L.A., Krasil’nikov S.Je. Organpreserving surgery for invasive cervical cancer // Sibirskij onkologicheskij zhurnal. 2011. № 2. P. 72–78. [in Russian]

9. Chernyshova A.L., Kolomiec L.A., Bochkareva N.V., Asadchikova O.N. Metabolic syndrome, interraction with endometrial carcinogenesis // Sibirskij onkologicheskij zhurnal. 2008. № 5. P. 68–74. [in Russian]

10. Chojnzonov E.L., Pisareva L.F., Cherdynceva N.V., Bojarkina A.P., Odincova I.N., Martynova N.A. Cancer incidence in Siberia and Russian Far East. Cancer care service and ways of its improvement // Bjulleten’ Sibirskogo otdelenija Rossijskoj akademii medicinskih nauk. 2004. № 2. P. 41–47. [in Russian]

11. Chojnzonov E.L., Pisareva L.F., Zhujkova L.D. Cancer incidence in the Tomsk region during the period 2004–2009. Assessment of diagnostic quality // Sibirskij onkologicheskij zhurnal. 2011. № 3. P. 29–34. [in Russian]

12. Alouini S., Rida K., Mathevet P. Cervical cancer complicating pregnancy: implications of laparoscopic lymphadenectomy // Gynecol. Oncol. 2008. Vol. 108 (3). P. 472–477. doi: 10.1016/j.ygyno.2007.12.006.

13. Amant F., Van Calsteren K., Halaska M., Beijnen J., Lagae L., Hanssens M., Heyns L., Lannoo L., Ottevanger N.P., Vanden Bogaert W., Ungar L., Vergote I., du Bois A. Gynecologic Cancers in Pregnancy: Guidelines of an International Consensus Meeting // Int. J. Gynecol. Cancer. 2009. Vol. 19. Suppl. 1. S. 1–12. doi: 10.1111/IGC.0b013e3181a1d0ec.

14. Dargent D., Martin X., Sacchetoni A., Mathevet P. Laparoscopic vaginal radical trachelectomy: a treatment to preserve the fertility of cervical carcinoma patients // Cancer. 2000. Vol. 88. P. 1877–1882.

15. Dargent D. Radical trachelectomy: an operation that preserves the fertility of young women with invasive cervical cancer // Bull. Acad. Natl. Med. 2001. Vol.185 (7). P. 1295–1304.

16. Dargent D. Using radical trachelectomy to preserve fertility in early invasive cervical cancer // Contemporary OB/GYN. 2000. P. 23–49.

17. Dargent D., Burn J.L., Roy M., Remi I. Pregnancies following radical trachelectomy for invasive cervical cancer [abstract] // Gynecol. Oncol. 1994. Vol. 52. P. 105.

18. Karam A., Feldman N., Holschneider C.H. Neoadjuvant cisplatin and radical cesarean hysterectomy for cervical cancer in pregnancy // Nat. Clin. Pract. Oncol. 2007. Vol. 4. P. 375–380.

19. Palaia I., Pernice M., Graziano M., Bellati F., Panici P.B. Neoadjuvant chemotherapy plus radical surgery in locally advanced cervical cancer during pregnancy: a case report // Am. J. Obstet. Gynecol. 2007. Vol. 197. P. e5-e6.

20. Salafia C.M., Minior V.K., Lopez-Zeno J.A., Whittington S.S., Pezzullo J.C., Vintzileos A.M. Relationship between placental histologic features and umbilical cord blood gases in preterm gestations // Int. J. Med. Sci. 1995. Vol. 173 (4). P. 1058–1064.

21. Ungar L., Palfalvi L., Hogg R., Siklós P., Boyle D.C., Del Priore G., Smith J.R. Abdominal radical trachelectomy: a fertility-preserving option for women with early cervical cancer // Br. J. Gynaecol. 2005. Vol. 112 (3). P. 366–369.


Review

For citations:


Chernyshova А.L., Kolomiets L.А., Gyunter V.E., Chekalkin Т.L. FORMATION OF OBTURATOR APPARATUS IN LOWER UTERINE SEGMENT IN PATIENTS WITH INVASIVE CERVICAL CANCER AFTER RADICAL TRANSABDOMINAL TRACHELECTOMY. Siberian journal of oncology. 2014;(5):39-44. (In Russ.)

Views: 585


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1814-4861 (Print)
ISSN 2312-3168 (Online)