PERITONEAL CARCINOMATOSIS
Abstract
The literature review examines the main pathological and morphogenetic aspects of the development of peritoneal carcinomatosis and its molecular and biological features. In addition, the basic principles of peritoneal carcinomatosis classification have been presented and groups of tumors, which may be complicated by dissemination to the peritoneum, have been designated. Particular attention is paid to the problems of diagnosis and treatment.
About the Authors
I. V. Stepanov
Tomsk Cancer Research Institute
Siberian State Medical University, Tomsk
Russian Federation
5, Kooperativny Street, 634050-Tomsk
Russian Federation
5, Kooperativny Street, 634050-Tomsk
Yu. М. Paderov
Siberian State Medical University, Tomsk
Russian Federation
5, Kooperativny Street, 634050-Tomsk
Russian Federation
5, Kooperativny Street, 634050-Tomsk
S. G. Afanasyev
Tomsk Cancer Research Institute
Russian Federation
Russian Federation
References
1. Abdullaev A.G., Polockij B.E., Pajanidi Ju.G., Zhordania K.I., Davydov M.I. Peritoneal pseudomixoma // Onkoginekologija. 2012. № 4. P. 25–34. [in Russian]
2. Afanas’ev S.G., Dobrodeev A.Ju. Cytoreductive surgery (Should the primary tumor be removed? (What is the optimal cytoreduction?) // Prakticheskaja onkologija. 2014. Vol. 15 (2). P. 93–100. [in Russian]
3. Davydov M.I., Ter-Ovanesov M.D., Bujdenok Ju.V., Polockij B.E., Gorbunova V.A., Abdullaev A.G. Intraoperative hyperthermic intraperitoneal chemotherapy in gastric cancer: a real possibility to improve the prognosis? // Vestnik RONC im. N.N. Blohina RAMN. 2010. Vol. 21 (1). P. 11–20. [in Russian]
4. Minimal clinical recommendations of the European Society of Medical Oncology (ESMO). M., 2010. P. 348–352. [in Russian]
5. Odishelidze N.V., Chistjakov S.S., Gabunija Z.R. Diagnostic importance of subclinical intraperitoneal dissemination in gastric cancer patients // Rossijskij medicinskij zhurnal. Prilozhenie Onkologija. 2011. Vol. 2. P. 49. [in Russian]
6. Petrovskaja N.A., Vozmitel’ M.A., Horuzhik S.A., Istomin Ju.P. Multimodal treatment of peritoneal carcinomatosis in experimental studies // Onkologicheskij zhurnal. 2011. T. 5, № 4 (20). S. 60–68. [in Russian]
7. Smirnova G.F., Kirichenko A.D., Fetisova T.I., Lopatin O.L., Verzhbickaja N.E., Egorov A.A. Rare case of disseminated peritoneal leiomyomatosis // Sibirskij onkologicheskij zhurnal. 2010. № 1. P. 85–87. [in Russian]
8. Shelepova V.M. Determining the site of the primary cancer in patients with metastasis of unknown origin using tumor markers // Rossijskij bioterapevticheskij zhurnal. 2001. Vol. 1 (3). P. 34–40. [in Russian]
9. Shpenkova A.A. Ovarian cancer: Treatment efficiency depending on the differentiation grade of carcinomatosis or unresolved problems of staging // Vestnik Novgorodskogo gosudarstvennogo universiteta. 2010. № 59. P. 116–120. [in Russian]
10. Akiyama H., Yamaoka H., Tanaka K., Ishikawa T., Ichikawa Y., Wakasugi J., Nagashima Y., Shimada H. Continuous hyperthermic peritoneal perfusion for peritoneal dissemination of gastric cancer // Hepatogastroenterology. 1998. Vol. 45 (24). P. 2079–2086.
11. Bando E., Kawamura T., Kinoshita K., Takahashi S., Maeda A., Osada S., Tsubosa Y., Yamaguchi S., Uesaka K., Yonemura Y. Magnitude of serosal changes predicts peritoneal recurrence of gastric cancer // J. Am. Coll. Surg. 2003. Vol. 197 (2). P. 212–222.
12. Barnetson R.J., Burnett R.A., Downie I., Harper C.M., Roberts F. Immunohistochemical analysis of peritoneal mesothelioma and primary and secondary serous carcinoma of the peritoneum: antibodies to estrogen and progesterone receptors are useful // Am. J. Clin. Pathol. 2006. Vol. 125 (1). P. 67–76.
13. Bozzetti F., Bonfanti G., Morabito A., Bufalino R., Menotti V., Andreola S., Doci R., Gennari L. A multifactorial approach for the prognosis of patients with carcinoma of the stomach after curative resection // Surg. Gynecol. Obstet. 1986. Vol. 162 (3). P. 229–234.
14. Carr N.J., Emory T.S., Sobin L.H. Epithelial neoplasms of the appendix and colorectum: an analysis of cell proliferation, apaptosis and expression of p53, CD44, bcl-2 // Arch. Pathol. Lab. Med. 2002. Vol. 126 (1). P. 837–841.
15. Ceelen W.P., Hesse U., Hemptinne В., Pattyn P. Hyperthermic intraperitoneal chemoperfusion in the treatment of locally advanced intraabdominal cancer // Brit. J. Surg. 2000. Vol. 87. P. 1006–1015.
16. Costamagna D., Scuderi S., Vaira M., Barone R., De Simone M. Treatment of peritoneal mesothelioma using cytoreduction and intraperitoneal hyperthermic chemotherapy // Tumori. 2003. Vol. 89. P. 40–42.
17. Cotte E., Passot G., Gilly F.N., Glehen O. Selection of patients and staging of peritoneal surface malignancies // World J. Gastrointest. Oncol. 2010. Vol. 2 (1). P. 31–35. doi: 10.4251/wjgo.v2.i1.31.
18. Deraco M., Santoro N., Carraro O., Inglese M.G., Rebuffoni G., Guadagni S., Somers D.C., Vaglini M. Peritoneal carcinomatosis: feature of dissemination. A review // Tumori. 1999. Vol. 85. P. 1–5.
19. Elias D., Glehen O., Pocard M., Quenet F., Goéré D., Arvieux C., Rat P., Gilly F. A comparative study of complete cytoreductive surgery plus intraperitoneal chemotherapy to treat peritoneal dissemination from colon, rectum, small bowel, and nonpseudomyxoma appendix // Ann. Surg. 2010. Vol. 251 (5). P. 896–901. doi: 10.1097/SLA.0b013e3181d9765d.
20. Faryammanesh R., Lange T., Magbanua E., Haas S., Meyer C., Wicklein D., Schumacher U., Hahn U. SDA, a DNA Aptamer Inhibiting E- and P-Selectin Mediated Adhesion of Cancer and Leukemia Cells, the First and Pivotal Step in Transendothelial Migration during Metastasis Formation // PLoS One. 2014 Vol. 9 (4). E. 93173. doi: 10.1371/journal. pone.0093173.
21. Gebauer F., Wicklein D., Stübke K., Nehmann N., Schmidt A., Salamon J., Peldschus K., Nentwich M.F., Adam G., Tolstonog G., Bockhorn M., Izbicki J.R., Wagener C., Schumacher U. Selectin binding is essential for peritoneal carcinomatosis in a xenograft model of humanpancreatic adenocarcinoma in pfp-/rag2-mice // Gut. 2013. Vol. 62 (5). P. 741–750. doi: 10.1136/gutjnl-2011-300629.
22. Glehen O., Gilly F.N., Boutitie F., Bereder J.M., Quenet F., Sideris L., Mansvelt B., Lorimier G., Msika S., Elias D. Toward curative treatment of peritoneal carcinomatosis from nonovarian origin by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy: a multi-institutional study of 1,290 patients // Cancer. 2010. Vol. 116 (24). P. 5608–5618. doi: 10.1002/cncr.25356.
23. Harmon R.L., Sugarbaker P.H. Prognostic indicators in peritoneal carcinomatosis from gastrointestinal cancer // Int. Semin. Surg. Oncol. 2005. Vol. 2 (1). P. 3.
24. Hood J.D., Cheresh D.A. Role of integrins in cell invasion and migration // Nat. Rev. Cancer. 2002. Vol. 2. P. 91–100.
25. Jacquet P., Vidal-Jove J., Zhu B., Sugarbaker P. Peritoneal carcinomatosis from gastrointestinal malignancy: natural history and new prospects for management // Acta Chir. Belg. 1994. Vol. 94 (4). P. 191–197.
26. Japanese Classification of Gastric Carcinoma. 2nd English Edition Gastric Cancer // Gastric Cancer. 1998. Vol. 1. P. 10–24.
27. Kianmanesh R., Ruszniewski P., Rindi G., Kwekkeboom D., Pape U.F., Kulke M., Sevilla Garcia I., Scoazec J.Y., Nilsson O., Fazio N., Lesurtel M., Chen Y.J., Eriksson B., Cioppi F., O’Toole D. ENETS Consensus Guidelines for the Management of Peritoneal Carcinomatosis from Neuroendocrine Tumors // Neuroendocrinology. 2010. Vol. 91. P. 333–340. doi: 10.1159/000286700.
28. Li G., Zhang Z., Ma X., Zhu J., Cai G. Postoperative chemoradiotherapy combined with epirubicin-based triplet chemotherapy for locally advanced adenocarcinoma of the stomach or gastroesophageal junction // PLoS One. 2013. Vol. 8 (1). E. 54233. doi: 10.1371/journal. pone.0054233.
29. Marhaba R., Zöller M. CD44 in cancer progression: adhesion, migration and growth regulation // J. Mol. Histol. 2004. Vol. 35. P. 211–231.
30. Nakanishi H., Kodera Y., Torii A., Hirai T., Yamamura Y., Kato T., Kito T., Tatematsu M. Detection of carcinoembryonic antigen-expressing free tumor cells in peritoneal washes from patients with gastric carcinoma by polymerase chain reaction // Jpn. J. Cancer Res. 1997. Vol. 7. P. 687–692.
31. Nomura E., Niki M., Fujii K., Shinohara H., Nishiguchi K., Sonoda T., Tanigawa N. Efficacy of intraperitoneal and intravenous chemotherapy and left upper abdomen evisceration for advanced gastric cancer // Gastric Cancer. 2001. Vol. 4. P. 75–82.
32. Peinado H., Olmeda D., Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? // Nat. Rev. Cancer. 2007. Vol. 7 (6). P. 415–428.
33. Perrot G., Langlois B., Devy J., Jeanne A., Verzeaux L., Almagro S., Sartelet H., Hachet C., Schneider C., Sick E., David M., Khrestchatisky M., Emonard H., Martiny L., Dedieu S. LRP-1-CD44, a new cell surface complex regulating tumor cell adhesion // Mol. Cell. Biol. 2012. Vol. 32. P. 3293–3307. doi: 10.1128/MCB.00228-12.
34. Rivard J.D., McConnell Y.J., Temple W.J., Mack L.A. Cytoreduction and heated intraperitoneal chemotherapy for colorectal cancer: are we excluding patients who may benefit? // J. Surg. Oncol. 2014. Vol. 109 (2). P. 104–109. doi: 10.1002/jso.23446.
35. Scaringi S., Kianmanesh R., Sabate J.M., Facchiano E., Jouet P., Coffin B., Parmentier G., Hay J.M., Flamant Y., Msika S. Advanced gastric cancer with or without peritoneal carcinomatosis treated with hyperthermic intra-peritoneal-chemotherapy: A single western center experience // Eur. J. Surg. Oncol. 2008. Vol. 34 (11). P. 1246–1252. doi: 10.1016/j. ejso.2007.12.003.
36. Serafino A., Zonfrillo M., Andreola F., Psaila R., Mercuri L., Moroni N., Renier D., Campisi M., Secchieri C., Pierimarchi P. CD44- targeting for antitumor drug delivery: a new SN-38-hyaluronan bioconjugate for locoregional treatment of peritoneal carcinomatosis // Curr. Cancer Drug. Targets. 2011. Vol. 11 (5). P. 572–585.
37. Spiliotis J.D., Halkia E.A., Efstathiou E. Peritoneal carcinomatosis 2011; it’s about time for chemosurgery // J. BUON. 2011. Vol. 16 (3). P. 400–408.
38. Sugarbaker P.H. Cytoreduction including total gastrectomy for pseudomyxoma peritonei // Brit. J. Surg. 2002. Vol. 89. P. 208–212.
39. Sugarbaker P.H. Overview of peritoneal carcinomatosis // Cancerologia. 2008. Vol. 3. P. 119–124.
40. Sugarbaker P.H. Peritoneal surface oncology: review of a personal experience with colorectal and appendiceal malignancy // Tech. Coloproctol. 2005. Vol. 9 (2). P. 95–103.
41. Thiery J.P. Epithelial-mesenchymal transitions in tumour progression // Nat. Rev. Cancer. 2002. Vol. 2. P. 442–454.
42. Votanopoulos K.I., Swett K., Blackham A.U., Ihemelandu C., Shen P., Stewart J.H., Levine E.A. Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy in Peritoneal Carcinomatosis from Rectal Cancer // Ann. Surg. Oncol. 2013. Vol. 20 (4). P. 1088–1092. doi: 10.1245/ s10434-012-2787-3.
43. Wagner B.J., Löb S., Lindau D., Hörzer H., Gückel B., Klein G., Glatzle J., Rammensee H.G., Brücher B.L., Königsrainer A. Simvastatin reduces tumor cell adhesion to human peritoneal mesothelial cells by decreased expression of VCAM-1 and 1 integrin // Int. J. Oncol. 2011. Vol. 39. P. 1593–1600. doi: 10.3892/ijo.2011.1167.
44. Yang X.J., Li Y., al-shammaa Hassan A.H., Yang G.L., Liu S.Y., Lu Y.L., Zhang J.W., Yonemura Y. Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival in selected patients with peritoneal carcinomatosis from abdominal and pelvic malignancies: results of 21 cases // Ann. Surg. Oncol. 2009. Vol. 16 (2). P. 345–351. doi: 10.1245/s10434-008-0226-2.
45.
Review
For citations:
Stepanov I.V., Paderov Yu.М., Afanasyev S.G. PERITONEAL CARCINOMATOSIS. Siberian journal of oncology. 2014;(5):45-53. (In Russ.)
Views:
2035
Email this article 
