NEW OPPORTUNITIES FOR SURGICAL TREATMENT OF PATIENTS WITH INITIALLY UNRESECTABLE UTERINE CERVIX CANCE
https://doi.org/10.21294/1814-4861-2016-15-1-44-48
Abstract
A new multimodality approach has been developed for management of locally advanced cervical cancer, including neoadjuvant chemotherapy with chemoembolization of two uterine arteries, a subsequent brachytherapy treatment at a dose of 10 Gy and type III hysterectomy or pelvic exenteration; this approach has made it possible to attain tumor resectability in 83.3 % of the cases, to avoid severe toxic, intraoperative and postoperative morbidities with a 90.5 % radicality of surgical intervention. This method produces satisfactory rates of 3-year overall observed survival, recurrence-free survival and metastasis-free survival being 82.3 %, 84.6 % and 88.4 % respectively.
About the Authors
I. A. Kosenko
N.N. Alexandrov National Cancer Centre of Belarus
Belarus
Belarus
MD, Professor, Principal Researcher, Gynecological Oncology Department,
223040, Lesnoy, Minsk District
T. M. Litvinova
Belarusian State Medical University
Belarus
Belarus
MD, DSc, Associate Professor of the Oncology Department,
Minsk
O. P. Matylevich
N.N. Alexandrov National Cancer Centre of Belarus
Belarus
Belarus
MD, DSc, Associate Professor of the Oncology Department,
223040, Lesnoy, Minsk District
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Review
For citations:
Kosenko I.A., Litvinova T.M., Matylevich O.P. NEW OPPORTUNITIES FOR SURGICAL TREATMENT OF PATIENTS WITH INITIALLY UNRESECTABLE UTERINE CERVIX CANCE. Siberian journal of oncology. 2016;15(1):44-48. (In Russ.) https://doi.org/10.21294/1814-4861-2016-15-1-44-48
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