ULTRASOUND DIAGNOSIS OF THROMBOSIS IN CANCER PATIENTS
https://doi.org/10.21294/1814-4861-2016-15-5-60-64
Abstract
Purpose. To identify the relationship between ultrasonographic signs of progression of venous thrombosis and procoagulant activity of malignant tumors.
Material and methods. A total of 225 cancer patients with concomitant venous thrombosis were examined. The study group (143 patients) and the control group (82 patients) were matched for tumor localization, types of venous thrombosis, prevention and treatment of venous thromboembolic complications, age and gender. The patients of the study group underwent palliative, symptomatic and diagnostic surgical procedures, and the patients of the control group underwent radical surgery for cancer. In postoperative period, all patients underwent ultrasound examination of the inferior vena cava, iliac veins and the veins of the lower extremity every 3 days for 12 days.
Results. In the study group, the majority of patients had echographic signs of progression of venous thrombosis. For the control group patients, good recanalization of venous thrombosis.
About the Authors
F. S. AkhmetzianovRussian Federation
I. A. Kamalov
Russian Federation
References
1. Sallah S., Wan J.Y., Nguyen N.P. Venous thrombosis in patients with solid tumors: determination of frequency and characteristics. Thromb Haemost. 2002 Apr; 87 (4): 575– 9.
2. Sorensen H.T., Mellemkjaer L., Olsen J.H., Baron J.A. Prognosis of cancers associated with venous thromboembolism. N Engl J Med. 2000 Dec 21; 343 (25): 1846–50.
3. Gulyaev D.V. Efficacy and prospects of using anticoagulant agents in the treatment of cancer patients. Oncology. 2000; 2 (3): 218–224. [in Russian]
4. Agnelli G. Venous thrombosis and cancer: a two-way clinical association. Thromb Haemost. 1997 Jul; 78 (1): 117–20.
5. Stricker H. Venous thromboembolism and cancer: pathophysiology and incidence. Vasa. 2014 Jul; 43 (4): 239–43. doi: 10.1024/0301-1526/a000358.
6. Baron J.A., Gridley G., Weiderpass E., Nyrén O., Linet M. Venous thromboembolism and cancer. Lancet. 1998 Apr 11; 351 (9109): 1077–80.
7. Prandoni P., Lensing A.W., Büller H.R., Cogo A., Prins M.H., Cattelan A.M., Cuppini S., Noventa F., ten Cate J.W. Deep-vein thrombosis and the incidence of subsequent symptomatic cancer. N Engl J Med. 1992 Oct 15; 327 (16): 1128–33.
Review
For citations:
Akhmetzianov F.S., Kamalov I.A. ULTRASOUND DIAGNOSIS OF THROMBOSIS IN CANCER PATIENTS. Siberian journal of oncology. 2016;15(5):60-64. (In Russ.) https://doi.org/10.21294/1814-4861-2016-15-5-60-64