TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER
https://doi.org/10.21294/1814-4861-2017-16-1-71-75
Abstract
Between 2008 and 2015, 82 patients with inoperable esophageal cancer were treated with radiation therapy. The patients were divided into 3 groups. Group I consisted of 30 patients, who received external beam radiation therapy (EBRT) in combination with brachytherapy. Group II and group III patients (30 and 22 patients, respectively) received EBRT alone. Patients of group II received EBRT at a total dose of 60–70 Gy and patients of group III received EBRT at a total dose of 40–50 Gy. Treatment outcomes were better in patients treated with combination of EBRT and brachytherapy than in patients treated with EBRT alone. There was no significant difference between groups 2 and 3 with regard to their survival rates. Two-year overall survival rates in group I, II and III were 36 %, 12 % and 12 % and the median overall survival time was 15.7; 9.7 and 6.6 months, respectively.
About the Authors
A. A. Lozhkov
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
Russian Federation
Russian Federation
MD, radiation therapist
SPIN-code: 5652-3448
A. V. Vazhenin
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
South Ural State Medical University, Chelyabinsk
Russian Federation
Russian Federation
MD, Member of the Russian Academy of Sciences, Professor, Chief Physician, Chelyabinsk Regional Clinical Oncology Center; Head of the Department of Oncology, Diagnostic Imaging and Radiation Therapy, South Ural State Medical University
SPIN-code: 1350-9411
T. M. Sharabura
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
South Ural State Medical University, Chelyabinsk
Russian Federation
MD, PhD, Head of Radiation Therapy Department, Chelyabinsk Regional Clinical Oncology Center; Lecturer, Department of Oncology, Diagnostic Imaging and Radiation Therapy, South Ural State Medical University
Russian Federation
MD, PhD, Head of Radiation Therapy Department, Chelyabinsk Regional Clinical Oncology Center; Lecturer, Department of Oncology, Diagnostic Imaging and Radiation Therapy, South Ural State Medical University
K. I. Kulaev
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
South Ural State Medical University, Chelyabinsk
Russian Federation
MD, Head of Endoscopy Department
Russian Federation
MD, Head of Endoscopy Department
K. S. Zuykov
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
Russian Federation
MD, Physician-endoscopist
Russian Federation
MD, Physician-endoscopist
I. M. Usupov
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
Russian Federation
MD, Physician-endoscopist
Russian Federation
MD, Physician-endoscopist
E. Y. Mozerova
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
South Ural State Medical University, Chelyabinsk
Russian Federation
MD, PhD, Chelyabinsk Regional Clinical Oncology Center; Lecturer, Department of Oncology, Diagnostic Imaging and Radiation Therapy, South Ural State Medical University
Russian Federation
MD, PhD, Chelyabinsk Regional Clinical Oncology Center; Lecturer, Department of Oncology, Diagnostic Imaging and Radiation Therapy, South Ural State Medical University
O. N. Davidova
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
Russian Federation
MD, Radiologist
Russian Federation
MD, Radiologist
M. M. Pimenova
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
South Ural State Medical University, Chelyabinsk
Russian Federation
MD, Radiologist
Russian Federation
MD, Radiologist
K. N. Siroleva
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
Russian Federation
MD, Radiologist
Russian Federation
MD, Radiologist
A. U. Maksimovskaya
Chelyabinsk Regional Clinical Oncology Center, Chelyabinsk
Russian Federation
Radiologist
Russian Federation
Radiologist
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Review
For citations:
Lozhkov A.A., Vazhenin A.V., Sharabura T.M., Kulaev K.I., Zuykov K.S., Usupov I.M., Mozerova E.Y., Davidova O.N., Pimenova M.M., Siroleva K.N., Maksimovskaya A.U. TREATMENT OUTCOMES OF EXTERNAL BEAM RADIOTHERAPY COMBINED WITH HIGH-DOSE-RATE BRACHYTHERAPY IN PATIENTS WITH ESOPHAGEAL CANCER. Siberian journal of oncology. 2017;16(1):71-75. (In Russ.) https://doi.org/10.21294/1814-4861-2017-16-1-71-75
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