THE EXPERIENCE OF USING ULTRASOUND WITH CONTRAST ENHANCEMENT IN THE DIAGNOSIS OF CERVICAL CANCER
https://doi.org/10.21294/1814-4861-2017-16-3-57-64
Abstract
The purpose of the study was to evaluate the value of contrast-enhanced ultrasound in detecting local spread, regional and distant metastases from cervical cancer. Materials and methods. The findings of contrast-enhanced ultrasound examination of 4 cervical cancer patients (IB1–IVB) treated at N.N. Blokhin Russian Cancer Research Center from September to October 2016 were evaluated. The HI VISION Ascendus device was used. Ultrasound patterns in different phases of contrast-enhanced accumulation and excretion were analyzed. Results. Our first experience in using contrast-enhanced ultrasound in the detection of local spread, regional and distant metastases from cervical cancer allowed us to study the structure of the tumor and its spread in greater detail. Conclusion. A small number of observations do not yet allow us to draw serious conclusions about the capabilities of this modern technology.
About the Authors
M. A. Chekalova
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
Russian Federation
MD, DSc, Professor
SPIN-code: 5221-8294
23, Kashirskoe shosse, 115230-Moscow
Z. R.-B., Musaeva
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
Russian Federation
MD
23, Kashirskoe shosse, 115230-Moscow
V. S. Kryazheva
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
Russian Federation
MD, Postgraduate
23, Kashirskoe shosse, 115230-Moscow
V. V. Kuznetsov
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
Russian Federation
MD, DSc, Professor, Leading Researcher, Gynecology Department
23, Kashirskoe shosse, 115230-Moscow
A. G. Margaryan
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
Russian Federation
MD, Head of Department, scientific Advisory outpatient diagnostic and treatment methods
SPIN-code: 8397-2968
23, Kashirskoe shosse, 115230-Moscow
References
1. Axel E.A. Morbidity and mortality from tumors of the female reproductive system in Russia. Gynecologic Oncology. 2015; 1: 6–15. [in Russian]
2. Bulanov M.N. Ultrasound gynecology. Moscow; 2012. [in Russian]
3. Piscaglia F., Nolsøe C., Dietrich C.F., Cosgrove D.O., Gilja O.H., Bachmann Nielsen M., Albrecht T., Barozzi L., Bertolotto M., Catalano O., Claudon M., Clevert D.A., Correas J.M., D’Onofrio M., Drudi F.M., Eyding J., Giovannini M., Hocke M., Ignee A., Jung E.M., Klauser A.S., Lassau N., Leen E., Mathis G., Saftoiu A., Seidel G., Sidhu P.S., ter Haar G., Timmerman D., Weskott H.P. The EFSUMB Guidelines and Recommendations on the Clinical Practice of Contrast Enhanced Ultrasound (CEUS): Update 2011 on non-hepatic applications. Ultraschall in Med. 2012; 33 (1): 33–59. doi: 10.1055/s-0031-1281676.
4. Ageev A.S., Chekalova M.A., Patyutko Yu.I., Polyakov A.N., Margaryan A.G. Ultrasound with contrast enhancement in the diagnosis of liver metastases. Ultrasonic and functional diagnostics. 2016. 2: 9–16. [in Russian]
5. Sencha A.N., Mogutov M.S., Patrons, Y.N., Penyaeva E.I., Karmanova A.V., Sencha E.A. opportunities of ultrasound with contrast enhancement in the diagnosis of thyroid cancer. Ultrasonic and functional diagnostics. 2015; 6: 10–26. [in Russian]
6. Lieng M., Qvigstad E., Dahl G.F., Istre O. Flow differences between endometrial polyps and cancer: a prospective study using intravenous contrast-enhanced transvaginal color flow Doppler and three-dimensional power Doppler ultrasound. Ultrasound Obstet Gynecol. 2008; 32 (7): 935–940.
7. Testa А.С., Ferrandina G., Fruscella E., Holsbeke C.V., Ferrazzi E., Leone F.P.G., Arduini D., Exacoustos C., Bokor D., Scambia G., Timmerman D. The Use of Contrasted Transvaginal Sonography in the Diagnosis of Gynecologic Diseases. J Ultrasound Med. 2005; 24 (9): 1267–1278.
8. Testa А.С., Тimmerman D.., Exacoustos C., Fruscella E., Holsbeke C.V., Bocor D., Arduini D., Scambia G., Ferrandina G. The role of CnTI-SonoVue in the diagnosis of ovarian masses with papillary projections: a preliminary study. Ultrasound Obstet Gynecol. 2007; 29 (5): 512–516.
9. Testa А.С., Тimmerman D., Van Belle V., Fruscella E., Holsbeke C.V., Savelli L., Ferrazzi E., Leone F.P.G. Intravenous contrast ultrasound examination using contrast-tuned imaging (CnTITM) and the contrast medium SonoVue for discrimination between benign and malignantadnexal masses with solid components. Ultrasound Obstet Gynecol. 2009; 34 (6): 699–710.
10. Greus C. Technology overview: SonoVue (Bracco, Milan). Eur. Radiol. 2004; 14 (Supp. 8): 420–430.
11. Seidel G., Meyer K. Impact of ultrasound contrast agents in cerebrovascular diagnostics. Eur J Ultrasound. 2002; 16 (1–2): 81–90.
12. Morel D.R., Schwieger I., Hohn L., Terrettaz J., Llul J.B., Cornioley Y.A., Schwieger M. Human pharmacokinetics and safety evaluation of SonoVue, a new contrast agent for ultrasound imaging. Invest. Radiol. 2000; 35 (1): 80–85.
13. Wilson S.R., Jang H.J., Kim T.K., Iijima H., Kamiyama N., Burns P.N. Real-Time Temporal Maximum-Intensity-Projection Imaging of Hepatic Lesions with Contrast-Enhanced Sonography. AJR Am J Roentgenol. 2008; 190 (3): 691–695.
14. Weskott H.-P. Contrast sonography. Ed. The 2 nd. Bremen: UniMed; 2014; 20–23. [in Russian]
Review
For citations:
Chekalova M.A., Musaeva Z.R., Kryazheva V.S., Kuznetsov V.V., Margaryan A.G. THE EXPERIENCE OF USING ULTRASOUND WITH CONTRAST ENHANCEMENT IN THE DIAGNOSIS OF CERVICAL CANCER. Siberian journal of oncology. 2017;16(3):57-64. (In Russ.) https://doi.org/10.21294/1814-4861-2017-16-3-57-64
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