MULTIMODALITY THERAPY FOR OSTEOSARCOMA OF THE STERNUM WITH RECONSTRUCTION OF COMPLEX CHEST WALL DEFECTS
https://doi.org/10.21294/1814-4861-2017-16-4-96-102
Abstract
Background. Osteosarcoma is a high-grade malignant bone tumor that accounts for up to 6 % of all bone neoplasms. There are only a few published cases of primary sternal osteosarcomas, reflecting the rarity of these tumors. Recently, there has been a growing interest in performing radical excisions of chest wall tumors followed by combined single-stage reconstruction of the rib cage with implants made of biologically compatible materials. Material and methods. We present the case of a 49-year-old woman diagnosed with osteosarcoma of the sternum. The patient received a combined modality treatment including chemotherapy, radiotherapy and surgery. Titanium nickelid implants were used for the reconstruction of chest wall defects. Results. The multimodality treatment with reconstruction of postoperative chest wall defects allowed the achievement of the optimal quality of life for 21 months in the patient with very poor prognosis. Conclusion. The chest wall reconstruction using biocompatible materials from titanium nickelid appeared to be an effective and safe technique for the treatment of chest wall tumors.
About the Authors
V. E. Ivanov
A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation.
Russian Federation
Russian Federation
Ivanov Vyacheslav E., MD, Research Scientist, Department of Radiation Therapy and Soft tissue and Bone sarcoma Surgery, A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre.
4, Korolev str., 249036-Obninsk, Russia.
A. A. Kurilchik
A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation.
Russian Federation
Russian Federation
Kurilchik Alexander A., MD, PhD, Leading Researcher, Department of Radiation Therapy and Soft tissue and Bone sarcoma Surgery, A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre.
4, Korolev str., 249036-Obninsk, Russia.
Yu. A. Ragulin
A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation.
Russian Federation
Russian Federation
Ragulin Yury A., MD, PhD, Head of the Department of Radiation Therapy and Thoracic and Breast Surgery, A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre.
4, Korolev str., 249036-Obninsk, Russia.
A. A. Zheravin
E.N. Meshalkin Siberian Biomedical Research Center, Ministry of Health of the Russian Federation.
Russian Federation
Russian Federation
Zheravin Alexandr A., MD, PhD, Head of Oncology and Radiotherapy Department, E.N. Meshalkin Siberian Biomedical Research Center.
15, Rechkunovskay str., 630055-Novosibirsk, Russia.
A. L. Starodubtsev
A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation.
Russian Federation
Russian Federation
Starodubtsev Alexey L., MD, Research Scientist, Department of Radiation Therapy and Soft tissue and Bone sarcoma Surgery, A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre.
4, Korolev str., 249036-Obninsk, Russia.
A. L. Zubarev
A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation.
Russian Federation
Russian Federation
Zubarev Alexey L., MD, PhD, Research Scientist, Department of Radiation Therapy and Soft tissue and Bone sarcoma Surgery, A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre.
4, Korolev str., 249036-Obninsk, Russia.
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Review
For citations:
Ivanov V.E., Kurilchik A.A., Ragulin Yu.A., Zheravin A.A., Starodubtsev A.L., Zubarev A.L. MULTIMODALITY THERAPY FOR OSTEOSARCOMA OF THE STERNUM WITH RECONSTRUCTION OF COMPLEX CHEST WALL DEFECTS. Siberian journal of oncology. 2017;16(4):96-102. (In Russ.) https://doi.org/10.21294/1814-4861-2017-16-4-96-102
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