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EPIDEMIOLOGY OF HOSPITAL-ACQUIRED INFECTIONS CAUSED BY HIGHLY RESISTANT STRAINS IN CANCER PATIENTS

https://doi.org/10.21294/1814-4861-2016-15-3-62-66

Abstract

The problem of the prevalence of multiple drug resistant (MDR) strains of Аcinetobacter baumannii in hospi- tals is a major challenge for cancer centers. To organize the measures for interrupting nosocomial transmis- sion and spread of nosocomial pathogens, it is important to determine the identity of the circulating strains of microorganisms. Assessment of the true phylogenetic relationships of the studied strains is possible by means of a cluster analysis of the isolates, followed by the construction and analysis of MSP Dendrogram in MALDI-TOF BIOTYPER system.

About the Authors

Z. V. Grigorievskaya
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
MD, DSc, Senior Researcher, Laboratory of Microbiological Diagnostics and Treatment of Infections in Oncology


I. N. Petukhova
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
MD, DSc, Senior Researcher, Laboratory of Microbiological Diagnostics and Treatment of Infections in Oncology


S. A. Dyakova
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
physician-microbiologist, Laboratory of Microbiological Diagnostics and Treatment of Infections in Oncology


N. V. Dmitrieva
N.N. Blokhin Russian Cancer Research Center, Moscow
Russian Federation
MD, Professor, Head of Laboratory of Microbiological Diagnostics and Treatment of Infections in Oncology


References

1. Grigorievskaya Z.V. Urgency of the problem of hospital infections in cancer patients // Vestnik RONC im. N.N. Blohina RAMN.. 2013. Vol. 24 (3–4). P. 46–49. [in Russian]

2. Grigorievskaya Z.V. Treatment strategy for nosocomial infections caused by resistant microorganisms in a cancer center. DSc thesis. M., 2015. 252 p. [in Russian]

3. Grigorievskaya Z.V., D’jakova. S.A. Occurrence and distribution of resistant microorganisms in hospitalas as a worldwide problem // Antimicrobial therapy for hospital-acquired infections / Eds. N.V. Dmitrieva, I.N. Petuhova. М., 2014. 326 p. [in Russian]

4. Davydov M.I., Dmitrieva N.V. Infections in oncology. М., 2009. 472 p. [in Russian]

5. Il’ina E.N. Creation of integrated genomic-proteomic system for typing and study of pathogens of bacterial and viral nature. DSc thesis. М., 2009. 264 p. [in Russian]

6. Antimicrobial resistance surveillance in Europe 2011. URL: http://www.ecdc.europa.eu (18.01.2016).

7. Chan J.M., Halachev M.R., Loman N.J., Constantinidou C., Pallen M.J. Defining bacterial species in the genomic era: insights from the genus Acinetobacter // BMC Microbiology. Vol. 12. P. 302. doi:10.1186/1471-2180-12-302.

8. Fishbain J., Peleg A.Y. Treatment of Acinetobacter infections // Clin. Infect. Dis. 2010. Vol. 51 (1). P. 79–84. doi: 10.1086/653120.

9. Tak-chiu W.U. Carbapenem-resistant or Multidrug-resistant Acinetobacter baumannii – a Clinical’s perspective // The Hong Kong Medical Diary. 2011. Vol. 16 (4). P. 6–9.

10. Vila J., Pachon J. Therapeutic options for Acinetobacter baumannii infections // Expert Opin. Pharmacother. 2008. Vol. 9 (4). P. 587–599. doi: 10.1517/14656566.9.4.587. Review.

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Review

For citations:


Grigorievskaya Z.V., Petukhova I.N., Dyakova S.A., Dmitrieva N.V. EPIDEMIOLOGY OF HOSPITAL-ACQUIRED INFECTIONS CAUSED BY HIGHLY RESISTANT STRAINS IN CANCER PATIENTS. Siberian journal of oncology. 2016;15(3):62-66. (In Russ.) https://doi.org/10.21294/1814-4861-2016-15-3-62-66

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ISSN 1814-4861 (Print)
ISSN 2312-3168 (Online)