MODERN METHODS OF TREATMENT OF PATIENTS WITH CANCER OF THE LARYNX AND HYPOPHARYNX
https://doi.org/10.21294/1814-4861-2016-15-3-91-96
Abstract
Laryngeal and hypopharyngeal cancer takes the leading position among malignant head and neck tumors, representing one of the most important and socially significant problems in modern oncology. Approaches to the treatment of locally advanced laryngeal or hypopharyngeal cancer have changed significantly in the recent years, due to new anticancer drugs and the widespread use of the best types of chemotherapy combined with surgery and radiotherapy.
About the Authors
E. L. Choinzonov
Tomsk Cancer Research Institute, Tomsk, Siberian State Medical University, Tomsk
Russian Federation
MD, DSc, Academician of RAS, Professor, Director
Russian Federation
MD, DSc, Academician of RAS, Professor, Director
Yu. V. Belevich
Tomsk Cancer Research Institute, Tomsk
Russian Federation
Junior Researcher, Chemotherapy Department
Russian Federation
Junior Researcher, Chemotherapy Department
S. Yu. Chizhevskaya
Tomsk Cancer Research Institute, Tomsk
Russian Federation
MD, DSc, Leading researcher, Department head and neck tumors
Russian Federation
MD, DSc, Leading researcher, Department head and neck tumors
V. E. Goldberg
Tomsk Cancer Research Institute, Tomsk
Russian Federation
MD, DSc, Professor, Chemotherapy Department
Russian Federation
MD, DSc, Professor, Chemotherapy Department
I. G. Frolova
Tomsk Cancer Research Institute, Tomsk
Russian Federation
MD, DSc, Professor, Radiology Department
Russian Federation
MD, DSc, Professor, Radiology Department
V. I. Chernov
Tomsk Cancer Research Institute, Tomsk
Russian Federation
MD, DSc, Professor, Department of nuclear medicine
Russian Federation
MD, DSc, Professor, Department of nuclear medicine
A. V. Goldberg
Tomsk Cancer Research Institute, Tomsk
Russian Federation
Junior Researcher, Radiology Department
Russian Federation
Junior Researcher, Radiology Department
References
1. Alieva S.B., Tkachev S.I., Zaderenko I.A. Variants of chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the pharynx // Opuholi golovy i shei. 2011. № 1. P. 26–30. [in Russian]
2. Andreev V.G., Pankratov V.A., Rozhnov V.A. Combined treatment of locally advanced laryngeal cancer with simultaneous preoperative radiotherapy and polychemotherapy in combination with means radiomodifying // Oncosurgery. 2008. № 2. P. 82. [in Russian]
3. Baryshev V.V., Rozhnov V.A., Andreev V.G., Gulidov I.A., Pankratov V.A., Bujakova M.E., Vdovina S.N. The effectiveness of re-radiation therapy combined with intratumoral chemotherapy in the treatment of unresectable regional metastases of the larynx and hypopharynx cancer // Nuclear Medicine and Radiation Safety. 2009. Vol. 54 (4). P. 58–62. [in Russian]
4. Bitjuckij P.G. Functionally-sparing surgery for the combined treatment of laryngeal cancer // Medical consultation. 2000. № 4. P. 15–45. [in Russian]
5. Bojkov V.P., Gladilina I.A., Pavljuk D.Ju., Strukov I.G. Therapeutic tactics in hypopharynx cancer // Practical oncology. 2003. Vol. 4. № 1. P. 51–55. [in Russian]
6. Bolotina L.V., Kravcov S.A., Kornieckaja A.L., Bojko A.V. Preliminary analysis of the effectiveness of induction chemotherapy withinconserving treatment of larynx and hypopharynx cancer // Oncosurgery. Special Issue № 1. 2013. P. 28–29. [in Russian]
7. Vakker A.V. Combined treatment of laryngeal cancer // Medical News. 2006. № 10. P. 90–92. [in Russian]
8. Vinogradov V.V., Larichev A.B., Klochihin A.L. Features of healing of postoperative wounds of the neck and the effectiveness of the combined treatment of the larynx and hypopharynx cancer // Bulletin of St. Petersburg State University. Surgery. Ser. 11. 2008. Rel. 1. P. 50–55. [in Russian]
9. Gervas P.A., Litvjakov N.V., Popova N.O., Dobrodeev A.Ju., Tarasova A.S., Jumov E.L., Ivanova F.G., Cheremisina O.V., Afanas’ev S.G., Gol’dberg V.E., Cherdynceva N.V. Problems and prospects for improving the molecular genetic diagnosis for the purpose of targeted drugs in oncology // Siberian Journal of Oncology. 2014. № 2. P. 46–55. [in Russian]
10. Klochihin A.L., Trofimov E.I., Zelenkin E.M. Immediate and longterm functional and environmental outcomes in patients laringektomirovannyh // Medical consultation. 2007. № 4. P. 16–20. [in Russian]
11. Kozhanov L., Sdvizhkov A., Romanova E. Functionally-sparing surgery for cancer of the larynx with the endoprosthesis // Journal of N.N. Blokhin Russian Cancer Research Center RAMS. Vol. 20, № 2 (1). 2009. P. 76–77. [in Russian]
12. Maslennikova A.V., Il’in N.V., Terent’ev I.G. Chemoradiation therapy and thermoradiotherapy prognostically unfavorable pharynx and larynx cancer // Russian Journal of Oncology. № 6. 2006. P. 28-31. [in Russian]
13. Muhamedov M.R., Cheremisina O.V., Chojnzonov E.L., Kul’bakin D.E., Balackaja L.N., Vasil’ev N.V., Gjunter V.Je. A modern look at an integrated approach to the diagnosis, treatment and rehabilitation of patients with laryngeal cancer // Russian otorhinolaryngology. 2012. № 3. P. 78–84. [in Russian]
14. Pankratov V.A., Andreev V.G., Kurpeshev O.K., Gulidov I.A., Orlova A.V. The results of the combined treatment of locally advanced laryngeal cancer using preoperative therapy termohimioluchevoy // Questions of Oncology. 2013. Vol. 59, № 6. С. 721–724. [in Russian]
15. Pankratov V.A., Andreev V.G., Rozhnov V.A. The simultaneous use of chemotherapy and radiation therapy in self-conservative and combined treatment of patients with locally advanced cancer of the larynx and hypopharynx // Siberian Journal of Oncology. 2007. № 1. P. 18–22. [in Russian]
16. Perevodchikova N.I. Guide chemotherapy of tumor diseases. М., 2011. P. 512. [in Russian]
17. Pis’mennyj V.I. Surgical treatment of cancer of the larynx // Journal of N.N. Blokhin Russian Cancer Research Center RAMS. Vol. 20, № 2 (1). 2009. P. 83. [in Russian]
18. Podvjaznikov S.O., Bjahov M.Ju. Experience of paroxetine in chemotherapy squamous cell carcinoma of the head and neck // Modern oncology. 2004. Vol. 4, № 3. P. 15–18. [in Russian]
19. Reshetov I.V., Chissov V.I., Trofimov E.I. Hypopharynx cancer. М., 2006. P. 280. [in Russian]
20. Reshetov I.V. Rehabilitation of cancer patients // Selected lectures in clinical oncology. М., 2002. P. 375. [in Russian]
21. Rozhnov V.A., Andreev V.G., Bujakova M.E. Features radiation therapy in recurrent laryngeal cancer // Journal of N.N. Blokhin Russian Cancer Research Center RAMS. 2009. Vol. 20, № 2 (1). P. 85–86. [in Russian]
22. Svetickij P.V., Kalij V.V., Volkova V.L. Reconstructive surgery in patients with locally advanced laryngeal cancer // Kuban Research Medical Gazette. 2010. № 2. P. 37–38. [in Russian]
23. Sivkovich O.O. Drug therapy in the treatment of locally advanced laryngeal cancer // Oncosurgery. 2012. Vol. 4, № 4. P. 51–53. [in Russian]
24. Slobina E.L. Treatment of patients with cancer of the larynx mestnorasprostranёnnym using dynamic multifraktsionirovaniya dose // Journal of N.N. Blokhin Russian Cancer Research Center RAMS. 2009. Vol. 20, № 2 (1). P. 87. [in Russian]
25. Tkachjov S.I., Alieva S.B. Chemoradiotherapy for locally advanced squamous cell carcinoma of the head and neck // Journal of N.N. Blokhin Russian Cancer Research Center RAMS. 2006. Vol. 17, № 2 (1). P. 51–52. [in Russian]
26. Chernov V.I., Zel’chan R.V., Tickaja A.A., Sinilkin I.G., Chizhevskaja S.Ju., Surkova P.V., Chojnzonov E.L. Using the combined image and single-photon emission computed tomography in the diagnosis of cancer of the larynx and hypopharynx // Nuclear Medicine and Radiation Safety. 2011. Vol. 56, № 2. P. 38–43. [in Russian]
27. Chizhevskaja S.Ju., Chojnzonov E.L. The effectiveness of chemoradiation therapy in the combined treatment of patients with cancer of the larynx and hypopharynx // Journal of N.N. Blokhin Russian Cancer Research Center RAMS. 2009. Vol. 20, № 2 (1). P. 88–89. [in Russian]
28. Chizhevskaja S.Ju., Musabaeva L.I., Kicmanjuk Z.D. The use of fast neutrons of 6.3 MeV in the treatment of malignant tumors in the head and neck // In: Fast neutrons in Oncology, ed. L.I. Musabaeva. Tomsk, 2000. P. 29–82. [in Russian]
29. Chissov V.I., Starinskij V.V., Petrova G.V. Malignancies in Russia in 2008 (morbidity and mortality). М., 2010. P. 36–37. [in Russian]
30. Chissov V.I., Reshetov I.V., Trofimov E.I. Modified tracheostomy in surgical treatment of patients with locally advanced and recurrent malignant tumors of the larynx and hypopharynx // Oncosurgery. 2011. Vol. 3, № 1. P. 4–10. [in Russian]
31. Chojnzonov E.L., Muhamedov M.R., Balackaja L.N. Laryngeal cancer. Modern aspects of treatment and rehabilitation. Tomsk, 2006. P. 280. [in Russian]
32. Chojnzonov E.L., Balackaja L.N. Quality of life of cancer patients as a criterion for evaluating the effectiveness of treatment and rehabilitation // Siberian bulletin Psychiatry and Addiction. 2008. № 3. P. 36–38. [in Russian]
33. Ушаков В.С., Иванов С.В. Рак гортани: современные возможности и перспективы // Практическая онкология. 2003. Т. 4, № 1. С. 56–60.
34. Caponigro F., Massa E., Manzione L., Rosati G., Biglietto M., De Lucia L., Sguotti C., Sganga P., Avallone A., Comella P., Mantovani G., Comella G. Docetaxel and cisplatin in locally advanced or metastatic squamous-cell carcinoma of the head and neck: a phase II study of the Southern Italy Cooperative Oncology Group (SICOG) // Ann. Oncol. 2001. Vol. 12 (2). P. 199–202.
35. Dietz A., Keilholz U., Werner J., Hagen R., Flentje M., Iro H. Current role for induction chemotherapy in head and neck tumors //Laryngorhinootologie. 2008. Vol. 87 (4). P. 237–243. doi: 10.1055/s-2007-995588.
36. Murphy B.A. Carcinoma of the head and neck // Handbook of cancer chemotherapy. Skeel R.T., Khleif S.N. (eds). 8 th Edition. Lippincott Williams & Wilkins, 2011. P. 69–93.
37. Pergolizzi S., Santacaterina A., Adamo B., Franchina T., Denaro N., Ferraro P., Settineri N., Adamo V. Induction chemotherapy with paclitaxel and cisplatin to concurrent radiotherapy and weekly paclitaxel in the treatment of loco-regionally advanced, stage IV (M0), head and neck squamous cell carcinoma. Mature results of a prospective study // Radiat. Oncol. 2011. Vol. 6. P. 162. doi: 10.1186/1748-717X-6-162.
38. Pointreau Y., Garaud P., Chapet S., Sire C., Tuchais C., Tortochaux J., Faivre S., Guerrif S., Alfonsi M., Calais G. Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation // J. Natl. Cancer Inst. 2009. Vol. 101 (7). P. 498–506. doi: 10.1093/jnci/djp007.
39. Sarini J., Bocciolini C., Fournier C., Penel N., Kara A., Van J.T., Lefebvre J.L. Induction chemotherapy and larynx preservation: is such practice useful? // Bull. Cancer. 2002. Vol. 89 (44). P. 411–417.
40. Zeng J., Yu Q.W., Liu W.W., Zeng Z.Y. Combined usage of taxotere in induction chemotherapy of head and neck neoplasms // Ai Zheng. 2003. Vol. 22 (8). P. 877–879.
41.
Review
For citations:
Choinzonov E.L., Belevich Yu.V., Chizhevskaya S.Yu., Goldberg V.E., Frolova I.G., Chernov V.I., Goldberg A.V. MODERN METHODS OF TREATMENT OF PATIENTS WITH CANCER OF THE LARYNX AND HYPOPHARYNX. Siberian journal of oncology. 2016;15(3):91-96. (In Russ.) https://doi.org/10.21294/1814-4861-2016-15-3-91-96
Views:
1015
Email this article 
