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THE CHOICE OF SURGICAL TACTICS BASED ON THE RESULTS OF PIGMENTED LIMPHOGRAPHY FOR PATIENTS WITH LOCALLY ADVANCED PROXIMAL GASTRIC CANCER

https://doi.org/10.21294/1814-4861-2017-16-2-13-19

Abstract

Introduction. The lack of low-cost and available methods for the diagnosis of lymph node metastasis from gastric cancer and the standards of surgery for proximal gastric cancer is a hot topic for research. the aim of research is to study the effectiveness of the method of pigment lymphography and to develop criteria for determining the extent of surgery in the treatment of locally advanced proximal gastric cancer.

Material And Methods. The study included 68 patients with locally advanced proximal gastric cancer. All patients were divided into 2 groups according to the extent of surgery: proximal subtotal gastric resection and gastrectomy. For intraoperative detection of lymph node metastases, the method of peroral pigmented lymphography was used.

Results. The sensitivity, specificity and accuracy of pigment lymphography in detecting lymph node metastases were 99.0 %, 89.8 % and 93.4 %, respectively. The developed algorithm for the choice of the extent of surgery for proximal gastric cancer demonstrated advantage of proximal subtotal resection over gastrectomy in terms of overall survival (66.4 ± 13.2 % versus 48.7 ± 16.9 %, p=0.021).

Conclusion. Peroral pigmented lymphography was shown to be an effective method in detecting lymph node metastases from gastric cancer.  Proximal subtotal gastrectomy in patients with locally advanced gastric cancer improved long-term treatment outcomes.

About the Authors

M. O. Maksimov
N.F. Katanov Khakass State University; Republican Clinical Oncological Dispensary
Russian Federation

Maksimov Maxim O. - MD, Associate Professor of the Department of Surgery with course Urology, Oncology, Traumatology and Orthopedic of N.F. Katanov KhU; Deputy Chief Medical Officer, RCOD.

90, Lenina Street, 655000-Abakan. E-mail: maksimov.mo@mail.ru; 173, Tsukanovoy Street, 655009-Abakan. Author ID: 606630



S. A. Tuzikov
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Medical Sciences; Siberian State Medical University
Russian Federation

Tuzikov Sergey A. - MD, DSc., Professor, Head of The Thoracic and Abdominal Department, Cancer Research Institute, TNR MC RAS.

5, Kooperativny str., 634009-Tomsk; 2, Moskovsky tract, 634050-Tomsk. E-mail: tuzikovsa@oncology.tomsk.ru. SPIN-code: 5662-6431


G. N. Strizhakov
N.F. Katanov Khakass State University
Russian Federation

Strizhakov Gennadiy N. - MD, PhD, Associate Professor, Head of the Department of Surgery with course Urology, Oncology, Traumatology and Orthopedic of N.F. Katanov KhSU; Head of Surgical Thoracic and Abdominal department, RCOD.

90, Lenina Street, 655000-Abakan. E-mail: tao_onco@mail.ru. Author ID: 606631



E. O. Rodionov
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Medical Sciences
Russian Federation

Rodionov Evgeny O. - postgraduate of Thoracic and Abdominal Department, Cancer Research Institute.

5, Kooperativny str., 634009-Tomsk. E-mail: scorpion1612@list.ru. SPIN-code: 7650-2129 



S. V. Miller
Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Medical Sciences
Russian Federation

Miller Sergey V. - MD, DSc, Leading researcher, Thoracic and Abdominal Department.

5, Kooperativny str., 634009-Tomsk. E-mail: miller_sv@sibmail.com. SPIN-code: 6510-9849



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Review

For citations:


Maksimov M.O., Tuzikov S.A., Strizhakov G.N., Rodionov E.O., Miller S.V. THE CHOICE OF SURGICAL TACTICS BASED ON THE RESULTS OF PIGMENTED LIMPHOGRAPHY FOR PATIENTS WITH LOCALLY ADVANCED PROXIMAL GASTRIC CANCER. Siberian journal of oncology. 2017;16(2):13-19. (In Russ.) https://doi.org/10.21294/1814-4861-2017-16-2-13-19

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ISSN 1814-4861 (Print)
ISSN 2312-3168 (Online)